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公开(公告)号:EP0512528B1
公开(公告)日:1999-09-15
申请号:EP92107685.7
申请日:1992-05-07
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor: Wallach, David , Aderka, Dan , Engelmann, Hartmut
IPC: A61K38/00
CPC classification number: A61K38/1793
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公开(公告)号:EP0512528A2
公开(公告)日:1992-11-11
申请号:EP92107685.7
申请日:1992-05-07
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor: Wallach, David , Aderka, Dan , Engelmann, Hartmut
IPC: A61K37/02
CPC classification number: A61K38/1793
Abstract: Tumor Necrosis Factor Binding Proteins (TBPs) are useful in the treatment of autoimmune diseases and graft-versus-host reactions.
Abstract translation: 肿瘤坏死因子结合蛋白(TBPs)可用于治疗自身免疫性疾病和移植物抗宿主反应。
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3.Antibodies to TNF binding protein I and F (ab) fragments thereof 失效
Title translation: 抗体对TNF结合蛋白I和其F(ab)片段。公开(公告)号:EP0412486B1
公开(公告)日:1994-11-30
申请号:EP90115105.0
申请日:1990-08-06
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor: Wallach, David , Engelmann, Harmut , Aderka, Dan
IPC: C12P21/08 , A61K39/395 , G01N33/577 , G01N33/68 , C07K3/18
CPC classification number: C07K16/2866 , A61K38/00 , C07K14/7151
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公开(公告)号:EP0512528A3
公开(公告)日:1993-07-21
申请号:EP92107685.7
申请日:1992-05-07
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor: Wallach, David , Aderka, Dan , Engelmann, Hartmut
IPC: A61K37/02
CPC classification number: A61K38/1793
Abstract: Tumor Necrosis Factor Binding Proteins (TBPs) are useful in the treatment of autoimmune diseases and graft-versus-host reactions.
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5.Antibodies to TNF binding protein I and F (ab) fragments thereof 失效
Title translation: Antikörpergegen TNF-Bindungsprotein I und deren F(ab)-Fragmente。公开(公告)号:EP0412486A1
公开(公告)日:1991-02-13
申请号:EP90115105.0
申请日:1990-08-06
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor: Wallach, David , Engelmann, Harmut , Aderka, Dan
IPC: C12P21/08 , A61K39/395 , G01N33/577 , G01N33/68 , C07K3/18
CPC classification number: C07K16/2866 , A61K38/00 , C07K14/7151
Abstract: Antibodies to TNF Binding Protein I (TBP-I) and F(ab) fragments thereof are provided that can be used in diagnostic assays and pharmaceutical agents for either inhibiting or mimicking the effects of TNF on cells.
Abstract translation: 提供了针对TNF结合蛋白I(TBP-1)和F(ab)片段的抗体,其可用于诊断测定和用于抑制或模拟TNF对细胞的作用的药物。
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