Abstract:
본 발명은 유효성분으로서 식물 추출물을 함유하는 c-kit 단백질 억제용 조성물에 관한 것이다. 보다 구체적으로, 본 발명은 식물추출물로서 풍년화( Hamamelis japonica ), 적작약( Paeonia lactiflora ), 복사나무( Prunus persica ) 및 해당화( Rosa rugosa ) 추출물로 이루어진 군으로부터 선택된 1종 이상을 함유하는 c-kit 단백질 억제용 조성물에 관한 것이다. 본 발명에 따른 조성물은 유효성분으로서 함유된 식물추출물이 멜라노사이트(melanocyte)의 세포 표면 단백질인 c-kit 단백질의 활성을 억제하여 멜라닌(Melanin)의 생성을 저해할 수 있으므로 우수한 미백효과를 나타낸다. c-kit, 풍년화, 적작약, 복사나무, 해당화, 멜라노사이트, 멜라닌, 미백
Abstract:
A food composition for improving and preventing obesity is provided to promote a beta oxidation of fatty acids effectively, and prevent and reduce an accumulation of excessive fat. The food composition for improving and preventing obesity contains coumestrol, a coumesterol-containing natural materials or an extract thereof as an active component. The active component promotes expression of Carnitine Palmitoyl Transferase 1A gene to increase a beta oxidation of fatty acids. The food composition for improving and preventing obesity is formulated into drink, diet bar, chocolate, caramel, or confectionery. The coumestrol is contained in an amount of 0.02-10wt% based on the total composition.
Abstract:
본 발명은 진세노사이드 F1(20-O-β-D-글루코피라노실-20(S)-프로토파낙사트리올)과 EGCG((-)에피갈로카테킨-3-갈레이트)의 상승효과에 의한 용도에 관한 것으로, 더욱 상세하게는 상기 화합물들을 동시에 처리하는 것을 특징으로 하는, 자외선 조사로 유도되는 피부세포의 사멸을 방지하는 방법에 관한 것이다. 본 발명은 단독 처리시에는 효과가 없는 낮은 농도의 두 화합물을 혼합하여 처리함으로써 자외선 조사에 의해 유발되는 Bcl-2의 발현 감소를 효과적으로 억제하여 피부세포의 사멸을 방지하는 Bcl-2 발현 조절제로서의 용도를 제공한다. 또한, 암억제 유전자인 Rb 단백질의 탈인산화를 억제하여 안정화시킴으로써 자외선에 의한 피부세포의 손상을 방지하는 용도를 제공한다. 본 발명을 통해 단가가 높은 두 화합물을 낮은 농도(단독 사용시 각각 2.5배, 5배 농도 필요)로 사용함으로써 원료비를 낮추어 고기능성 제품을 보다 저렴한 가격에 공급할 수 있다.
Abstract:
PURPOSE: Provided is a controlling agent of Bcl-2 expression which characteristically contains ginsenoside F1(20-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the formula(1), as an active ingredient. It prevents apoptosis caused by radiating low doses of ultraviolet rays, while promoting apoptosis when radiating high doses of ultraviolet rays, therefore it removes the risk of cancers. CONSTITUTION: A controlling agent of the expression of Bcl-2 is characterized by containing ginsenoside F1(20-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol), which is represented by the formula(1), as an active ingredient. It inhibits the decrease of Bcl-2 expression caused by radiating ultraviolet rays. Therefore, it prevents apoptosis by the radiation of low doses of ultraviolet rays, but promotes apoptosis by the radiation of high doses of ultraviolet rays.
Abstract:
PURPOSE: A cosmetic composition for inhibiting skin aging obtained by allowing emulsion particles and a liposome to contain bio GF 1K using a skin-compatible emulsifier and nanoemulsion techniques is provided. Therefore, it maximizes the transdermal absorption rate and has an excellent effect on the prevention of skin aging such as wrinkles reduction. CONSTITUTION: An anti-aging cosmetic composition contains a metabolite of ginseng as an effective ingredient, an emulsifier, a co-emulsifier and a surfactant. The metabolite of ginseng contains 30 to 50% by weight of a compound K represented by the formula 1, 5 to 25% by weight of ginsenoside F1 represented by the formula 2 and 5 to 25% by weight of 20-o-£α-L-arabinopyranosyl|-20(S)-protopanaxadiol represented by the formula 3 as an active component and has a particle size of 30 to 500nm. In formula, R1 is o-Glc, R2 is OH, R3 is H. The emulsifier contains a liposome containing lecithin or lecithin derivatives.