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1.发明公开세코이소라리시레시놀(ＳＥＣＯ)의 제조방법 및 이를유효성분으로 함유하는 화장료 조성물 有权制备SECOISOLARICIRESINOL（SECO）的方法和包含SECO作为活性成分的化妆品组合物
公开(公告)号：KR1020040059270A
公开(公告)日：2004-07-05
申请号：KR1020020085863
申请日：2002-12-28
Applicant: (주)아모레퍼시픽
IPC: C08H7/00
Abstract: PURPOSE: A method for preparing secoisolariciresinol is provided to obtain a cosmetic composition having good absorptivity to the user's skin and excellent activity of inhibiting the formation of reactive oxygen species. CONSTITUTION: The method for preparing secoisolariciresinol comprises hydrolyzing flaxseed extract or secoisolariciresinol diglucoside separated therefrom. The hydrolysis is an acidic hydrolysis, alkaline hydrolysis or enzymatic hydrolysis. More particularly, the enzyme used in the enzymatic hydrolysis is selected from the group consisting of exo-glycolases and composite enzymes containing exo-glycolases. Further, the cosmetic composition contains the secoisolariciresinol in an amount of 0.0001 to 10 wt% based on the total weight of the composition.
Abstract translation: 目的：提供一种制备双异吲哚林醇的方法，以获得对使用者皮肤具有良好吸收性的化妆品组合物和抑制活性氧形成的优异活性。 构成：制备二异喹啉的方法包括水解亚麻籽提取物或与其分离的二异辛烯二醇二葡萄糖苷。 水解是酸性水解，碱性水解或酶水解。 更具体地，酶水解中使用的酶选自外消旋酶和含有外消旋酶的复合酶。 此外，化妆品组合物含有相对于组合物总重量为0.0001〜10重量％的二异辛烯硫酚。
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公开(公告)号：KR1020040059139A
公开(公告)日：2004-07-05
申请号：KR1020020085716
申请日：2002-12-28
Applicant: (주)아모레퍼시픽
IPC: A61K31/704
CPC classification number: A61K31/70
Abstract: PURPOSE: Provided is a controlling agent of Bcl-2 expression which characteristically contains ginsenoside F1(20-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the formula(1), as an active ingredient. It prevents apoptosis caused by radiating low doses of ultraviolet rays, while promoting apoptosis when radiating high doses of ultraviolet rays, therefore it removes the risk of cancers. CONSTITUTION: A controlling agent of the expression of Bcl-2 is characterized by containing ginsenoside F1(20-O-beta-D-glucopyranosyl-20(S)-protopanaxatriol), which is represented by the formula(1), as an active ingredient. It inhibits the decrease of Bcl-2 expression caused by radiating ultraviolet rays. Therefore, it prevents apoptosis by the radiation of low doses of ultraviolet rays, but promotes apoptosis by the radiation of high doses of ultraviolet rays.
Abstract translation: 目的：提供一种Bcl-2表达的控制剂，其特征在于含有式（1）所示的人参皂甙F1（20-O-β-D-吡喃葡萄糖基-20（S） - 原人参三醇）作为活性成分。 防止辐射低剂量紫外线引起的细胞凋亡，同时在辐射高剂量的紫外线时促进细胞凋亡，从而消除癌症的风险。 构成：Bcl-2表达的控制剂的特征在于将由式（1）表示的人参皂甙F1（20-O-β-D-吡喃葡萄糖基-20（S） - 原人参三醇）作为活性物质 成分。 它抑制由辐射紫外线引起的Bcl-2表达的降低。 因此，通过低剂量的紫外线辐射可防止细胞凋亡，但通过高剂量紫外线的辐射促进细胞凋亡。
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公开(公告)号：KR100909206B1
公开(公告)日：2009-07-23
申请号：KR1020020085863
申请日：2002-12-28
Applicant: (주)아모레퍼시픽
IPC: C08H7/00
Abstract: 본 발명은 아마씨(Flaxseed) 추출물을 산, 알칼리 또는 효소반응시켜 세코이소라리시레시놀(secoisolariciresinol; SECO)을 제조하는 방법 및 이를 함유하는 화장료 조성물에 관한 것으로, 구체적으로, 피부흡수율이 높고 ROS 생성 억제능이 뛰어난 세코이소라리시레시놀을 제조하는 방법, 그 중에서도, 특히 효소를 이용하는 제조방법 및 이를 함유하는 화장료 조성물에 관한 것이다.
아마씨, 항산화, Flaxseed, SDG, secoisolariciresinol diglucoside, SECO, secoisolariciresinol, 노화방지Abstract translation: 目的：提供一种制备开环异松油烯醇的方法，以获得对使用者的皮肤具有良好吸收性和抑制活性氧形成的优异活性的化妆品组合物。 组成：制备开环异松木醇的方法包括水解从其中分离出的亚麻籽提取物或开环异冰片烯醇二葡糖苷。 水解是酸水解，碱水解或酶水解。 更特别地，用于酶水解的酶选自外切糖基酶和含外切糖基酶的复合酶。 此外，基于组合物的总重量，化妆品组合物含有0.0001至10重量％的选择性异亚丙基三胺醇。
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公开(公告)号：KR100820072B1
公开(公告)日：2008-04-10
申请号：KR1020020085716
申请日：2002-12-28
Applicant: (주)아모레퍼시픽
IPC: A61K31/704
CPC classification number: A61K31/70
Abstract: 본 발명은 하기 화학식 1로 표현되는 진세노사이드 F1(20-O-β-D-글루코피라노실-20(S)-프로토파낙사트리올)을 유효성분으로 하는 Bcl-2 발현 조절제에 관한 것이다.
[화학식 1]
진세노사이드 F1, Bcl-2 발현 조절제, 세포사멸 억제제, Brn-3a 발현 억제제, 세포사멸 촉진제
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