公开(公告)号：WO1992011820A1

公开(公告)日：1992-07-23

申请号：PCT/US1991009713

申请日：1991-12-20

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  PATEL, Indrajit

IPC: A61B19/00

CPC classification number: A61J1/1487 ,  A61J1/10 ,  A61J1/1406 ,  A61L29/049 ,  A61M39/08 ,  C08K5/11 ,  C08L67/00 ,  C08L75/04 ,  C08L2666/02 ,  C08L2666/18 ,  C08L2666/06

Abstract: A non-PVC, non-DEHP material is provided for medical grade tubing (14). The material comprises a blend of polyurethane and polyester. The resultant tubing of the present invention has good low temperature characteristics, is autoclavable, and RF sealable. Accordingly, the resultant tubing (14) can be utilized for applications which heretofore have been filled in the marketplace by DEHP plasticized PVC tubing. In an embodiment, the material includes a citrate ester.

Abstract translation: 为医疗级管（14）提供非PVC非DEHP材料。 该材料包括聚氨酯和聚酯的混合物。 本发明的所得管具有良好的低温特性，可高压灭菌，并可RF密封。 因此，所得到的管道（14）可用于迄今为止已经通过DEHP增塑的PVC管道填充在市场中的应用。 在一个实施方案中，该材料包括柠檬酸酯。

公开(公告)号：WO1992011058A1

公开(公告)日：1992-07-09

申请号：PCT/US1991009709

申请日：1991-12-20

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  BISCHOF, Daniel, F. ,  WOLF, Ludwig, Jr. ,  FOLEY, John, T. ,  BRATTEN, William, R.

IPC: A61M37/00

CPC classification number: A61L2/0011 ,  A61L2/08 ,  A61M1/3681 ,  A61M1/3683 ,  B01J19/122 ,  C12N7/04

Abstract: A system and method for treating a fluid carrying a biological contaminant to which a photoactive material has been bound include a treatment device (20) that defines a flow passage with a gap (26). The system and method operate to establish a flow of fluid from the inlet end (68) of the gap (26) to the outlet end (70) of the gap (26). The system and method expose the fluid, as it transits the gap (26) to a source of radiation (52) that activates the photoactive material bound to the contaminant. The system and method also mix the fluid as it flows within the gap (26).

Abstract translation: 用于处理携带已经结合光敏材料的生物污染物的流体的系统和方法包括限定具有间隙（26）的流动通道的处理装置（20）。 系统和方法操作以建立从间隙（26）的入口端（68）到间隙（26）的出口端（70）的流体流。 当系统和方法将间隙（26）转移到激活与污染物结合的光活性材料的辐射源（52）时，暴露流体。 当流体在间隙（26）内流动时，系统和方法也混合流体。

公开(公告)号：WO1992010275A1

公开(公告)日：1992-06-25

申请号：PCT/US1991009309

申请日：1991-12-06

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DUFF, Daniel, H.

IPC: B01D61/00

CPC classification number: B01D61/22 ,  A61M1/265 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/3406 ,  A61M1/3603 ,  A61M2205/3334 ,  B01D61/14

Abstract: A processing system (30) separates a cellular rich suspension (32) into a cellular first constituent (36) and cellular-free second constituent (38). The system (30) includes a separation zone (40) that receives the cellular rich suspension (32) and discharges the first (36) and second constituents (38). The system (30) coordinates the flow of cellular rich suspension (32) into the separation zone (40) with the flow of cellular-free second constituent (38) from the separation zone (40) to get a desired nominal separation efficiency. The system (30) also recirculates the cellular first constituent (36) back into the zone (40). By continuously recirculating the cellular first constituent (36) back into the separation zone (40), the system (30) can get and maintain a desired volume of the first constituent (36), despite the volume of cellular rich suspension (32) that is processed. By continuously recirculating the cellular first constituent (36) back into the separation zone (40), the system (30) also can provide operating conditions within the separation zone (40) that maximize separation efficiencies but that, without the benefits of recirculation, could otherwise damage or traumatize the cellular first constituent (36).

公开(公告)号：WO1992009309A1

公开(公告)日：1992-06-11

申请号：PCT/US1991008900

申请日：1991-11-25

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  TU, Roger ,  THYAGARAJAN, Kalathi ,  MYERS, Harriet, Chan

IPC: A61L02/00

公开(公告)号：WO1992007608A1

公开(公告)日：1992-05-14

申请号：PCT/US1991008053

申请日：1991-10-30

Applicant: BAXTER INTERNATIONAL INC. ,  DEN HEIJER, Peter ,  TEIRSTEIN, Paul, S.

Inventor： BAXTER INTERNATIONAL INC. ,  SIRIMANNE, D., Laksen ,  CUTTER, Sandra, L. ,  KEMKEMIAN, Zohrab, Sarkis

IPC: A61M25/01

CPC classification number: A61M25/0105 ,  A61M25/01 ,  A61M25/0133

Abstract: A catheter system (10) includes a guide wire (12), a working catheter (22) and a torque device (78) for removably coupling the working catheter (22) to the guide wire (12) while enabling rotation of the guide wire (12) relative to the working catheter (22). Advancement of the guide wire (12) in a vascular system is enabled by rotating the guide wire (12) while the working catheter (22) is coupled thereto. A procedure for use of the catheter system (10) includes the simultaneous insertion of the guide wire (12) and working catheter (22) into a vascular system and independent rotation of the guide wire for steering the guide wire (12), with working catheter (22) coupled thereto, through the vascular system.

Abstract translation: 导管系统（10）包括导丝（12），工作导管（22）和扭矩装置（78），用于将工作导管（22）可移除地连接到导丝（12），同时能够使导丝 （12）相对于工作导管（22）。 导管（12）在血管系统中的推进是通过在工作导管（22）与其连接的同时转动导丝（12）来实现的。 使用导管系统（10）的过程包括将导丝（12）和工作导管（22）同时插入血管系统中，并且用于转向导丝（12）的导丝的独立旋转，工作 通过血管系统联接到其上的导管（22）。

公开(公告)号：WO1992004932A1

公开(公告)日：1992-04-02

申请号：PCT/US1991006517

申请日：1991-09-09

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  WOODGRIFT, Randal, W. ,  WELSH, Gregory, P.

IPC: A61M25/01

CPC classification number: A61M25/0111

Abstract: An adjustable contamination shield (10) includes a distal fitting (12), a proximal fitting (14) and a collapsible shield (16), disposed between said distal (12) and proximal (14) fittings for enclosing an adjustable space therebetween and for preventing contact with a portion (20) of the catheter (22) disposed between the distal (12) and proximal (14) fittings. The shield (16) is supported in a collapsed configuration and controlled expansion thereof is provided when the distal (12) and proximal (14) fittings are moved apart from observation through an expanded portion of the collapsible shield (16) when the distal (12) and proximal (14) fittings are moved apart from one another.

Abstract translation: 可调节的污染屏蔽（10）包括远端配件（12），近端配件（14）和可折叠防护罩（16），其设置在所述远端（12）和近端（14）配件之间，用于封闭其间的可调节空间 防止与设置在远端（12）和近端（14）配件之间的导管（22）的部分（20）接触。 当远端（12）和近端（14）接头远离可折叠屏蔽（16）的扩展部分时，当远端（12）和近端（14）配件远离观察穿过可伸缩护罩（16）的扩张部分时，护罩（16）被支撑成塌缩构型， ）和近端（14）配件彼此分开移动。

公开(公告)号：WO1992004072A1

公开(公告)日：1992-03-19

申请号：PCT/US1991006132

申请日：1991-08-27

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  HODGSON, William, S. ,  DHUWALIA, Jagdish, C. ,  PFLUEGER, Russell

IPC: A61M25/01

CPC classification number: A61M25/09033 ,  A61M2025/09166 ,  A61M2025/09175

Abstract: A guidewire (10) having a centrally located core wire (12) about which is mounted a single outer helical coil spring (14). The core wire (12) is typically longer than the outer helical coil spring (14), with the helical coil spring and core wire having common distal ends (20, 22). The spring (14) is brazed at both its distal and proximal end to the core wire (12). The distal brazing of the core wire (12) and helical coil springs (14) is rounded. A second small radiopaque helical coil spring (42) is fitted in the distal end of the outer helical coil spring (14) and brazed to the core wire (12) and outer helical coil spring (14) at a location proximal the helical coil spring distal end.

Abstract translation: 具有中心定位的芯线（12）的导丝（10）围绕其安装有单个外螺旋螺旋弹簧（14）。 芯线（12）通常比外螺旋弹簧（14）长，螺旋弹簧和芯线具有共同的远端（20,22）。 弹簧（14）在其远端和近端处钎焊到芯线（12）。 芯线（12）和螺旋形螺旋弹簧（14）的远端钎焊是圆形的。 第二个小的不透射线螺旋弹簧（42）装配在外部螺旋弹簧（14）的远端，并在接近螺旋螺旋弹簧的位置钎焊到芯线（12）和外部螺旋螺旋弹簧（14） 远端。

公开(公告)号：WO1992003658A1

公开(公告)日：1992-03-05

申请号：PCT/US1991005798

申请日：1991-08-15

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  D'SILVA, Edmund, D.

IPC: F04B49/10

CPC classification number: E05C3/045 ,  E05B17/0058 ,  F04B43/082

Abstract: A peristaltic pump comprising a housing (19), including a base (21), a resilient tube (27) and peristaltic pumping fingers (31) carried by the supporting structure. The tube (27) is positionable on the base (21) in a proper position and an improper position. In the proper position, the peristaltic pumping fingers (31) can properly progressively squeeze the tube to pump a fluid through the tube and in an improper position. A door (23) is mounted on the housing (19) for movement between an open position and a closed position. A latch (25) includes a pivotable latch member (51) on the door (23) and a fixed latch member (55) on the housing (19). The pivotable latch member (51) is movable between a latching position in which the door (23) is locked in the closed position and a releasing position in which the door (23) is not locked in the closed position. If the tube (27) is in the improper position, the pivotable latch member (51) is prevented from being placed in the latching position.

公开(公告)号：WO1992000769A1

公开(公告)日：1992-01-23

申请号：PCT/US1991004828

申请日：1991-07-09

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  PRINCE, Paul, R. ,  CALLAWAY, William, D.

IPC: A61M01/34

CPC classification number: A61M1/34 ,  A61M1/262 ,  A61M1/3403 ,  A61M1/341 ,  A61M2205/3331 ,  B01D61/22

Abstract: An adaptive filter concentrate flow control system and method includes a filter system (12), a pumping system (14) driving feed fluid, concentrate and filtrate flowing through the filter system (12) and a flow control system (18) controlling the pumping system (14) to maintain optimum filtrage flow rates or minimum feed flow rates along a control surface (102) in a three dimensional transmembrane pressure (feed fluid rate) filtrate flow rate space. Actual sensed operating point data is used to locate the control surface (102) so as to assure an optimized filtrate flow rate or minimized feed flow rate at which reversible blocking of the membrane has begun to occur without irreversible blocking or plugging. The system is advantageously employed to control and maximize the flow of plasma in a plasmapheresis system or to minimize the rate at which blood is withdrawn from a donor and introduced into the system while achieving a fixed rate of plasma flow.

公开(公告)号：WO1991019554A1

公开(公告)日：1991-12-26

申请号：PCT/US1991004193

申请日：1991-06-12

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  HWANG, Yean, Yow ,  RITCHEY, Brian ,  SCHOENDORFER, Donald, W.

IPC: B01D21/30

CPC classification number: A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3646 ,  A61M1/3672 ,  A61M1/3693 ,  A61M1/3696 ,  A61M2202/0427

Abstract: Method and apparatus are provided for machine separation of blood into blood components, wherein a preselected fluid such as anticoagulant is added to at least two different locations (16, 112) through the fluid flow path of the set (10), in order to promote the different functional characteristics in different blood components. The method results in reduced incidence of citrate reaction in the blood donor and increased platelet yield in platelet rich plasma (60) collected during the procedure.

Abstract translation: 在第一次操作中，将全血分离成分离器（46）中的组分以产生富含血小板的血浆，其中少量抗凝血剂足以防止凝血。 在全血流已经停止之后，进一步的抗凝血剂通过分离器（46），从而为富含血小板的血浆添加更多抗凝血剂以促进储存。 这允许在分离器中获得更高的血小板产量。