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公开(公告)号：WO1992011820A1
公开(公告)日：1992-07-23
申请号：PCT/US1991009713
申请日：1991-12-20
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BAXTER INTERNATIONAL INC. , PATEL, Indrajit
IPC: A61B19/00
CPC classification number: A61J1/1487 , A61J1/10 , A61J1/1406 , A61L29/049 , A61M39/08 , C08K5/11 , C08L67/00 , C08L75/04 , C08L2666/02 , C08L2666/18 , C08L2666/06
Abstract: A non-PVC, non-DEHP material is provided for medical grade tubing (14). The material comprises a blend of polyurethane and polyester. The resultant tubing of the present invention has good low temperature characteristics, is autoclavable, and RF sealable. Accordingly, the resultant tubing (14) can be utilized for applications which heretofore have been filled in the marketplace by DEHP plasticized PVC tubing. In an embodiment, the material includes a citrate ester.
Abstract translation: 为医疗级管（14）提供非PVC非DEHP材料。 该材料包括聚氨酯和聚酯的混合物。 本发明的所得管具有良好的低温特性，可高压灭菌，并可RF密封。 因此，所得到的管道（14）可用于迄今为止已经通过DEHP增塑的PVC管道填充在市场中的应用。 在一个实施方案中，该材料包括柠檬酸酯。
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2.发明申请MULTILAYER COEXTRUDED MATERIAL FOR MEDICAL GRADE PRODUCTS AND PRODUCTS MADE THEREFROM 审中-公开医用级产品及其制品的多层复合材料
公开(公告)号：WO1993015908A1
公开(公告)日：1993-08-19
申请号：PCT/US1993000594
申请日：1993-01-22
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BAXTER INTERNATIONAL INC. , PATEL, Indrajit , BOWERMAN, Harold , ROSENBAUM, Larry , MENNENOH, Rich , RYAN, Pat
IPC: B32B27/08
CPC classification number: A61J1/10 , A61J1/1406 , A61J1/1487 , A61L29/049 , A61M39/08 , B32B27/08 , C08K5/11 , C08L67/00 , C08L75/04 , C08L2666/06 , C08L2666/18 , C08L2666/02
Abstract: The present invention provides a non-PVC, non-DEHP material that can be used for medical grade tubing. Additionally, the present invention provides medical grade tubing made from such a material. To this end, the present invention provides a medical grade tubing (14 and 20), comprising a multilayer coextruded structure including: a layer comprising a blend of polyurethane and polyester; and a layer comprising a blend chosen from the group consiting of: polypropylene, ethylenevinyl acetate, and polyurethane; polypropylene and styrene-ethylene-butylene-styrene; polypropylene, styrene-ethylene-butylene-styrene, and ethylenevinyl acetate; polypropylene, ethylenevinyl acetate, styrene-ethylene-butylene-styrene, and thermoplastic polyester elastomer; polypropylene, ethylenevinyl acetate, styrene-ethylene-butylene-styrene, thermoplastic polyester elastomer, and polyurethane; polyester, thermoplastic polyester elastomer, and polyurethane; polyester and polyurethane; and polypropylene, styrene-ethylene-butylene-styrene, and polyurethane.
Abstract translation: 本发明提供了可用于医疗级管材的非PVC非DEHP材料。 另外，本发明提供了由这种材料制成的医用级管。 为此，本发明提供了一种医用级管（14和20），其包括多层共挤出结构，包括：包含聚氨酯和聚酯的共混物的层; 以及包含选自以下的混合物的层：聚丙烯，乙烯 - 乙酸乙烯酯和聚氨酯; 聚丙烯和苯乙烯 - 乙烯 - 丁烯 - 苯乙烯; 聚丙烯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯和乙烯 - 乙酸乙烯酯; 聚丙烯，乙烯乙酸乙烯酯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯和热塑性聚酯弹性体; 聚丙烯，乙烯乙酸乙烯酯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯，热塑性聚酯弹性体和聚氨酯; 聚酯，热塑性聚酯弹性体和聚氨酯; 聚酯和聚氨酯; 和聚丙烯，苯乙烯 - 乙烯 - 丁烯 - 苯乙烯和聚氨酯。
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公开(公告)号：WO1993014810A2
公开(公告)日：1993-08-05
申请号：PCT/US1993000595
申请日：1993-01-22
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BAXTER INTERNATIONAL INC. , PATEL, Indrajit , BOWERMAN, Harold , ROSENBAUM, Larry , MENNENOH, Rich , RYAN, Pat
IPC: A61M39/00
CPC classification number: A61J1/10 , A61J1/1406 , A61J1/1487 , A61L29/049 , A61M39/08 , B32B27/08 , C08K5/11 , C08L67/00 , C08L75/04 , C08L2666/06 , C08L2666/18 , C08L2666/02
Abstract: A non-PVC, non-DEHP material is provided for medical grade products such as tubing and containers. The material comprises a monolayer blend of a polyurethane based material. In an embodiment, the resultant product of the present invention has good low temperature characteristics, is autoclavable, and RF sealable. Accordingly, the resultant product can be utilized for applications which heretofore have been filled in the marketplace by DEHP plasticized PVC products.
Abstract translation: 非PVC非DEHP材料用于医疗级产品如管材和容器。 该材料包括聚氨酯基材料的单层共混物。 在一个实施方案中，本发明的所得产品具有良好的低温特性，可高压灭菌，并可RF密封。 因此，所得产品可用于迄今为止已经通过DEHP增塑PVC产品填充在市场中的应用。
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4.发明申请STEAM STERILIZABLE SYSTEM FOR INACTIVATING VIRAL CONTAMINANTS IN BODY FLUIDS 审中-公开用于在身体液体中灭活病毒污染物的蒸汽消毒系统
公开(公告)号：WO1994007426A1
公开(公告)日：1994-04-14
申请号：PCT/US1993009396
申请日：1993-10-04
Applicant: BAXTER INTERNATIONAL INC.
Inventor： BAXTER INTERNATIONAL INC. , DeBRAUWERE, Jack , MATHIAS, Jean-Marie , PATEL, Indrajit
IPC: A61B19/00
CPC classification number: A61J1/10 , A61K35/14 , A61L2/0023 , A61L2/0088 , A61L2/06 , A61L2/07 , A61L2/18 , C08L27/06 , C12N7/04
Abstract: A steam sterilizable unit (10) for inactivating pathogens in a body fluid is provided comprising a plastic structure for housing a therapeutically effective amount of a methylene blue solution. The plastic structure preferably includes at least an inner layer (128) constructed from a non-PVC plastic. Preferably, the methylene blue solution has a pH of less than 7.0 and preferably less than or equal to approximately 6.3.
Abstract translation: 提供一种用于灭活体液中的病原体的蒸汽灭菌单元（10），其包括用于容纳治疗有效量的亚甲基蓝溶液的塑料结构。 塑料结构优选至少包括由非PVC塑料构成的内层（128）。 优选地，亚甲基蓝溶液的pH值小于7.0，优选小于或等于约6.3。
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公开(公告)号：WO1990005496A1
公开(公告)日：1990-05-31
申请号：PCT/US1989005020
申请日：1989-11-06
Applicant: BAXTER INTERNATIONAL, INC.
Inventor： BAXTER INTERNATIONAL, INC. , PATEL, Indrajit
IPC: A61B19/00
CPC classification number: A61J1/10 , A61M1/0209 , C08K5/11
Abstract: A plastic composition is disclosed which has particular application in the manufacture of blood bags (40) and other medical products. The composition has anti-hemolytic effects when used in the storage of red blood cells. In connection with one aspect of the present invention, the plastic composition comprises the combination of a non-PVC plastic and a selected quantity citrate ester sufficient to suppress hemolysis of red blood cells. The non-PVC material is preferably a polyolefin copolymer. Materials other than citrate ester may also be used with polyolefin as a hemolysis suppressant.
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Patent Agency Ranking6.发明授权STEAM STERILIZABLE SYSTEM FOR INACTIVATING VIRAL CONTAMINANTS IN BODY FLUIDS 失效对于病毒灭活污染蒸汽sterillisable系统体液
公开(公告)号：EP0650345B1
公开(公告)日：1999-08-25
申请号：EP94900351.1
申请日：1993-10-04
Applicant: BAXTER INTERNATIONAL INC.
Inventor： DeBRAUWERE, Jack , MATHIAS, Jean-Marie , PATEL, Indrajit
CPC classification number: A61J1/10 , A61K35/14 , A61L2/0023 , A61L2/0088 , A61L2/06 , A61L2/07 , A61L2/18 , C08L27/06 , C12N7/04
Abstract: A steam sterilizable unit for inactivating pathogens in a body fluid is provided including a plastic structure for housing a therapeutically effective amount of a methylene blue solution. The plastic structure preferably includes at least an inner layer constructed from a non-PVC plastic. Preferably, the methylene blue solution has a pH of less than 7.0 and preferably less than or equal to approximately 6.3.
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公开(公告)号：EP0578804B1
公开(公告)日：2002-07-31
申请号：EP93903644.8
申请日：1993-01-22
Applicant: BAXTER INTERNATIONAL INC.
Inventor： PATEL, Indrajit , BOWERMAN, Harold , ROSENBAUM, Larry , MENNENOH, Rich , RYAN, Pat
CPC classification number: A61J1/10 , A61J1/1406 , A61J1/1487 , A61L29/049 , A61M39/08 , B32B27/08 , C08K5/11 , C08L67/00 , C08L75/04 , C08L2666/06 , C08L2666/18 , C08L2666/02
Abstract: A non-PVC, non-DEHP material is provided for medical grade products such as tubing and containers. The material comprises a monolayer blend of a polyurethane based material. In an embodiment, the resultant product of the present invention has good low temperature characteristics, is autoclavable, and RF sealable. Accordingly, the resultant product can be utilized for applications which heretofore have been filled in the marketplace by DEHP plasticized PVC products.
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公开(公告)号：EP0516818B1
公开(公告)日：1998-08-12
申请号：EP92903136.7
申请日：1991-12-20
Applicant: BAXTER INTERNATIONAL INC.
Inventor： PATEL, Indrajit
IPC: A61L29/00
CPC classification number: A61J1/1487 , A61J1/10 , A61J1/1406 , A61L29/049 , A61M39/08 , C08K5/11 , C08L67/00 , C08L75/04 , C08L2666/02 , C08L2666/18 , C08L2666/06
Abstract: A non-PVC, non-DEHP material is provided for medical grade tubing (14). The material comprises a blend of polyurethane and polyester. The resultant tubing of the present invention has good low temperature characteristics, is autoclavable, and RF sealable. Accordingly, the resultant tubing (14) can be utilized for applications which heretofore have been filled in the marketplace by DEHP plasticized PVC tubing. In an embodiment, the material includes a citrate ester.
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公开(公告)号：EP0578804A1
公开(公告)日：1994-01-19
申请号：EP93903644.0
申请日：1993-01-22
Applicant: BAXTER INTERNATIONAL INC.
Inventor： PATEL, Indrajit , BOWERMAN, Harold , ROSENBAUM, Larry , MENNENOH, Rich , RYAN, Pat
CPC classification number: A61J1/10 , A61J1/1406 , A61J1/1487 , A61L29/049 , A61M39/08 , B32B27/08 , C08K5/11 , C08L67/00 , C08L75/04 , C08L2666/06 , C08L2666/18 , C08L2666/02
Abstract: L'invention se rapporte à un matériau non PVC et non DEHP pour produits d'usage médical tels que des tubes et des récipients. Ce matériau comprend un mélange monocouche d'un matériau à base de polyuréthane. Dans un mode de réalisation particulier, le produit obtenu dans la présente invention présente de bonnes caractéristiques à basse température, il peut être soumis à autoclave et il est scellable par HF. Ainsi, ce produit peut être utilisé dans des applications qui jusqu'à présent ont été satisfaites dans le commerce par des produits en PVC plastifiés par DEHP.
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公开(公告)号：EP0396724A1
公开(公告)日：1990-11-14
申请号：EP89913055.0
申请日：1989-11-06
Applicant: BAXTER INTERNATIONAL INC.
Inventor： PATEL, Indrajit
CPC classification number: A61J1/10 , A61M1/0209 , C08K5/11
Abstract: Composition plastique utilisable tout particulièrement dans la fabrication de sacs pour conserver le sang (40) et autres produits médicaux. Ladite composition a des effets anti-hémolytiques lorsqu'utilisée pour conserver des globules rouges. Selon l'un des modes de réalisation de la présente invention, la composition plastique se compose d'une combinaison d'un plastique qui n'est pas du chlorure de polyvinyle (CPV) et d'une quantité d'ester de citrate suffisante pour empêcher l'hémolyse des globules rouges. Le matériau plastique non CPV est de préférence un copolymère de polyoléfine. On peut également utiliser des matériaux autres que l'ester de citrate avec la polyoléfine comme agent anti-hémolyse.
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