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公开(公告)号：WO2002088681A1
公开(公告)日：2002-11-07
申请号：PCT/JP2002/004035
申请日：2002-04-23
IPC: G01N21/35
CPC classification number: G01N21/3563 , G01J3/02 , G01J3/0218 , G01J3/0221 , G01J3/0256 , G01J3/0272 , G01J3/0291 , G01J3/26 , G01J3/2803 , G01N33/025 , G01N2021/317 , G01N2021/8466 , G01N2201/0221 , G01N2201/08 , G01N2201/0826 , G01N2201/084
Abstract: In order to easily carry out a non-destructive inspection of an object to be inspected at any work site by using a compact and handy type inspection instrument, a spectroscope assembly comprising an optical fiber shaping and holding member capable of arranging and maintaining the output end of an optical fiber bundle in such a way that the thickness is uniform and the bundle is flat, a packaged compact spectroscope in which a linear continuous variable interference filter, a micro-lens array, and a linear silicon array sensor are assembled in this order from the light input window toward the opposite side in a package in which a slit-like light input window through which the light from a linear light output surface enters is defined in a side surface facing the linear light output surface of the optical fiber shaping and holding member, and a positioning means for disposing the linear light output surface of the optical fiber bundle so as to face the light input window is provided in a body case together with a sensor head.
Abstract translation: 为了通过使用紧凑且方便的型式检查仪器在任何工地容易地进行对被检查对象的无损检查，包括能够布置和保持输出端的光纤成形和保持构件的分光器组件 以使得厚度均匀且束平坦的方式形成光纤束，其中以该顺序组装线性连续可变干涉滤光器，微透镜阵列和线性硅阵列传感器的封装小型分光镜 在光输入窗口朝向相对侧，其中来自线形光输出表面的光进入的狭缝状光输入窗口被限定在面对光纤成形的线性光输出表面的侧表面中，并且 以及用于将光纤束的线性光输出表面设置为面对光输入窗口的定位装置设置在 主体外壳和传感器头。
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公开(公告)号：WO02054049A1
公开(公告)日：2002-07-11
申请号：PCT/GB2001/005585
申请日：2001-12-18
IPC: G01N21/64
CPC classification number: G01N21/6452 , G01N21/6456 , G01N21/76 , G01N2021/6484 , G01N2201/0826 , G01N2201/0833
Abstract: A fibre optic epi-fluorescence imaging system in which the optical fibres are rearranged so that the system can be used for measuring luminescence samples. The system comprises at least two optical fibres (32, 46) or bundles of fibres which lead to a CCD camera (74), the fibres or bundles of fibres from all samples being arranged in two sets, a first set which are formed from a non-fluorescing material and a second set which are formed from a material which may fluoresce but enables the fibres formed therefrom to have a higher numerical aperature than those of the first set.
Abstract translation: 光纤外延荧光成像系统，其中光纤被重新排列，使得该系统可用于测量发光样品。 该系统包括通向CCD照相机（74）的至少两根光纤（32,46）或纤维束，来自所有样品的纤维或纤维束被布置成两组，第一组由 非荧光材料和第二组，其由可以发荧光但使得由其形成的纤维具有比第一组更高的数值的材料形成。
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公开(公告)号：US11781989B2
公开(公告)日：2023-10-10
申请号：US17652941
申请日：2022-03-01
Applicant: ADVANCED NANO TECHNOLOGIES LIMITED
Inventor： Norman McMillan , Martina O'Neill , Sven Riedel , Liam McDonnell
IPC: G01N21/65
CPC classification number: G01N21/658 , G01N2201/023 , G01N2201/0224 , G01N2201/0826 , G01N2201/0833 , G01N2201/10
Abstract: A method of analysing a sample in the form of a droplet provided on a sample-receiving surface includes providing a light source and a detector in a housing, positioning said sample-receiving surface in or on the housing, and focussing an incident beam of light to a focal point in the vicinity of the sample. Light is detected from the sample resulting from an interaction with the sample, the sample-receiving surface, or the atmosphere surrounding the sample. At least one parameter of the detected light is measured, and the sample-receiving surface is translated relative to the housing such that the focal point is at a different region of the sample, the sample-receiving surface, or the atmosphere surrounding the sample. The step of measuring one or more parameters of the detected light is repeated following the translating step.
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公开(公告)号：US20230141269A1
公开(公告)日：2023-05-11
申请号：US17454461
申请日：2021-11-10
Applicant: Bay Jay Ray Technology Limited
Inventor： Renjie ZHOU , Mengxuan Niu , Rui Sun
CPC classification number: G01N21/6456 , G02B27/30 , G02B27/1006 , G02B27/149 , G01N21/6428 , G02B2207/113 , G01N2021/6439 , G01N2021/6463 , G01N2021/6484 , G01N2201/082 , G01N2201/0826 , G01N2201/12
Abstract: The disclosure herein provides a device, a method and a computer-readable storage medium for quantitative phase imaging, and relates to the field of quantitative phase imaging. The specific implementation scheme is: Obtain a multiplexed interferogram of the sample, where the multiplexed interferogram is a sample beam composed of at least two beams with different wavelengths to illuminate the sample and penetrate into the cube beam splitter Combine at least two beams with different wavelengths as the reference beam, and the combined beam is the imaging image sampled by the camera; and perform phase retrieval on the multiplexed interference image to obtain each beam of the sample in the composite sample beam The phase map at the wavelength of Using the embodiments of the disclosure herein, one imaging acquisition and one phase retrieval are to acquire the phase maps of at least two wavelength channels.
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公开(公告)号：US20190064069A1
公开(公告)日：2019-02-28
申请号：US16112048
申请日：2018-08-24
Applicant: FUJIFILM Corporation
Inventor： Takuji TADA
CPC classification number: G01N21/6456 , G01N21/645 , G01N21/76 , G01N2021/6478 , G01N2021/6484 , G01N2201/0826 , G02B3/005 , G02B3/0056 , G02B3/0062 , G02B3/0075 , G02B3/06 , G02B26/0875
Abstract: Provided is a fluorescence reading device capable of narrowing a distance between a lens unit and an observation object to a distance according to a focal length of a refractive index distribution type lens and focusing fluorescence emitted from the observation object on detecting unit without blurring.Optical fiber sub-bundles equivalent to a light guide unit are buried in lens holding parts of a lens unit. Emission ends of the optical fiber sub-bundles are exposed to upper surfaces of the lens holding parts that face the observation object holding unit. The optical fiber sub-bundles guide the excitation light emitted from the light source and radiate the guided excitation light toward the surface of an observation object that faces the lens unit.
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Patent Agency Ranking
公开(公告)号：US20180284017A1
公开(公告)日：2018-10-04
申请号：US15471852
申请日：2017-03-28
Applicant: TE Connectivity Corporation
Inventor： Soren Grinderslev , Igor Stouklov , Mark Benton
CPC classification number: G01N21/4133 , G01F23/00 , G01N21/552 , G01N21/94 , G01N2021/945 , G01N2201/0826
Abstract: A sensor for detecting the level of accumulation of a material along an axis in a fluid environment, the sensor comprising (a) an optically transparent body having a third refractive index and an exposed surface defining a length extending at least partially in the direction of the axis; (b) at least one light delivery source for delivering light to the body such that the light is distributed along the length of the exposed surface; and at least one light receiver for receiving reflected light from the length of the exposed surface, wherein the amount of the reflected light depends on the level of the material accumulated along the length of the exposed surface
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公开(公告)号：US20180223335A1
公开(公告)日：2018-08-09
申请号：US15941383
申请日：2018-03-30
Applicant: Streck, Inc.
Inventor： Matthew R. Kreifels , Scott E. Whitney , Joel R. TerMaat
CPC classification number: C12Q1/686 , G01N21/645 , G01N21/6452 , G01N2021/6484 , G01N2201/0627 , G01N2201/0826 , G01N2201/0833
Abstract: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate reduced sample read time and rapid reading of multiple light wavelengths.
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公开(公告)号：US20180217048A1
公开(公告)日：2018-08-02
申请号：US15853022
申请日：2017-12-22
Applicant: TRUSTEES OF TUFTS COLLEGE
Inventor： DAVID R. WALT , KARRI LYNN MICHAEL-BALLARD
IPC: G01N15/14 , C12Q1/6837 , B01J19/00 , G01N33/543
CPC classification number: G01N15/1456 , B01J19/0046 , B01J2219/00317 , B01J2219/00459 , B01J2219/00466 , B01J2219/005 , B01J2219/00524 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00677 , B01J2219/00704 , B01J2219/00722 , B01J2219/00725 , B01J2219/0074 , B82Y30/00 , C12Q1/6837 , C40B40/06 , C40B40/10 , G01N21/6428 , G01N21/6452 , G01N21/6456 , G01N21/7703 , G01N21/78 , G01N33/543 , G01N33/54313 , G01N2015/1438 , G01N2021/6441 , G01N2021/6484 , G01N2035/0097 , G01N2201/0826 , Y02A50/55 , Y10S435/808 , Y10S436/805
Abstract: A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ability to identify the location of bioactive agents and particles within the array using an optically interrogatable, optical signature encoding scheme. A wide variety of modified substrates may be employed which provide either discrete or non-discrete sites for accommodating the microspheres in either random or patterned distributions. The substrates may be constructed from a variety of materials to form either two-dimensional or three-dimensional configurations. In a preferred embodiment, a modified fiber optic bundle or array is employed as a substrate to produce a high density array. The disclosed system and method have utility for detecting target analytes and screening large libraries of bioactive agents.
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公开(公告)号：US09958325B2
公开(公告)日：2018-05-01
申请号：US15624008
申请日：2017-06-15
Applicant: Metal Power Analytical (I) Pvt. Ltd.
Inventor： Priyadarshan Divyadarshan Pant
IPC: G01J3/28 , G01J3/06 , G01J3/02 , G01J3/04 , G01J3/443 , G01N21/31 , G01N21/33 , G01J3/18 , G01J3/32
CPC classification number: G01J3/06 , G01J3/0218 , G01J3/0232 , G01J3/04 , G01J3/18 , G01J3/2803 , G01J3/32 , G01J3/443 , G01J2003/045 , G01J2003/061 , G01J2003/065 , G01J2003/282 , G01N21/3103 , G01N21/33 , G01N2201/0826
Abstract: The present disclosure relates to the field of optical systems. The envisaged multi-scan optical system is compact and stable. The system comprises an excitation source, a hydra fiber cable, a wavelength selector, an optical element, and a detector. The excitation source is configured to emit composite light. The hydra fiber cable has a head and a plurality of tentacles, and is configured to receive the composite light via a second lens. The plurality of tentacles is configured to emit the composite light towards the wavelength selector which includes a plurality of optical slits (s1-s8) and a plurality of shutters. The wavelength selector is configured to selectively collect and filter the composite light directed by a first lens and the plurality of tentacles by means of the plurality of shutters. The detector is configured to detect the plurality of spectral line scans reflected by the optical element for spectrometric analysis.
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公开(公告)号：US09932632B2
公开(公告)日：2018-04-03
申请号：US13833349
申请日：2013-03-15
Applicant: Streck, Inc.
Inventor： Matthew R. Kreifels , Scott E. Whitney , Joel R. TerMaat
CPC classification number: C12Q1/686 , G01N21/645 , G01N21/6452 , G01N2021/6484 , G01N2201/0627 , G01N2201/0826 , G01N2201/0833
Abstract: An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space and facilitate reduced sample read time and rapid reading of multiple light wavelengths.
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