公开(公告)号：US4939170A

公开(公告)日：1990-07-03

申请号：US197009

申请日：1988-05-20

Applicant: Bernd-Wieland Kruger ,  Klaus Sasse ,  Peter Heitkamper ,  Klaus Konig ,  Wilhelm Brandes ,  Gerd Hanssler ,  Albrecht Marhold

Inventor： Bernd-Wieland Kruger ,  Klaus Sasse ,  Peter Heitkamper ,  Klaus Konig ,  Wilhelm Brandes ,  Gerd Hanssler ,  Albrecht Marhold

IPC: A01N47/22 ,  A01N47/30 ,  A01N53/00 ,  A01N53/06 ,  C07C67/00 ,  C07C201/00 ,  C07C205/26 ,  C07C205/37 ,  C07C205/43 ,  C07C213/00 ,  C07C213/02 ,  C07C215/76 ,  C07C239/00 ,  C07C271/40 ,  C07C271/48 ,  C07C275/28 ,  C07C275/34 ,  C07C301/00 ,  C07C303/40 ,  C07C311/08 ,  C07C311/21 ,  C07C311/31 ,  C07C311/37 ,  C07C313/00 ,  C07C317/36 ,  C07C317/38 ,  C07C317/40 ,  C07C323/39 ,  C07C323/49 ,  C07C333/04 ,  C07C333/06 ,  C07C333/08 ,  C07D307/08 ,  C07D309/08 ,  C07D319/06 ,  C07D521/00

CPC classification number: C07D307/08 ,  C07C205/26 ,  C07C205/37 ,  C07C275/34 ,  C07D319/06

Abstract: Fungicidal substituted aminophenyl carbamates of the formula ##STR1## in which X represents --CO--NR.sup.8 R.sup.9 ; --CO--OR.sup.9 ; --CO--SR.sup.9 ; --CO.sup.R.sup.10 ; --SO.sub.2 R.sup.9 or hydrogen, in whichR.sup.8 represents hydrogen or alkyl,R.sup.9 represents optionally substituted aryl, optionally substituted aralkyl, optionally substituted alkyl, alkenyl, halogenoalkenyl, or in each case optionally substituted cycloalkyl, cycloalkenyl or cycloalkylalkyl, andR.sup.10 has the meaning of R.sup.9 or represents an optionally substituted heterocyclic ring,Y.sup.1 to Y.sup.4 are identical or different and represent hydrogen, halogen, nitro, cyano, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylthio, alkylsulfonyl or halogenoalkythio,R.sup.1 to R.sup.7 are identical or different and represent hydrogen, alkyl, halogenoalkyl or alkoxyalkyl,n represents 0 or 1, andZ represents alkyl, halogenoalkyl or a ##STR2## radical, in which R.sup.11 to R.sup.14 are identical or different and represent hydrogen, alkyl, halogenoalkyl or alkoxyalkyl, andR.sup.15 represents alkyl, halogenoalkyl or alkoxyalkyl.

Abstract translation: 式（I）的杀真菌取代的氨基苯基氨基甲酸酯，其中X表示-CO-NR8R9; -CO-OR9; -CO-SR9; -COR10; -SO 2 R 9或氢，其中R 8表示氢或烷基，R 9表示任选取代的芳基，任选取代的芳烷基，任选取代的烷基，烯基，卤代烯基，或在每种情况下任选取代的环烷基，环烯基或环烷基烷基，R 10具有R 9 或代表任选取代的杂环，Y 1至Y 4相同或不同，表示氢，卤素，硝基，氰基，烷基，卤代烷基，烷氧基，卤代烷氧基，烷硫基，烷基磺酰基或卤代链烯基，R 1至R 7相同或不同， 烷基，卤代烷基或烷氧基烷基，n表示0或1，Z表示烷基，卤代烷基或基团，其中R11至R14相同或不同，表示氢，烷基，卤代烷基或烷氧基烷基，R15表示烷基，卤代烷基 或烷氧基烷基。

公开(公告)号：US4937374A

公开(公告)日：1990-06-26

申请号：US242679

申请日：1988-09-09

Applicant: Kevin Beautement ,  John M. Clough ,  Christopher R. A. Godfrey

Inventor： Kevin Beautement ,  John M. Clough ,  Christopher R. A. Godfrey

IPC: B01J23/06 ,  A01N37/38 ,  A01N37/40 ,  A01N41/04 ,  A01N41/06 ,  A01N41/10 ,  A01N43/10 ,  A01N43/20 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/54 ,  A01N43/58 ,  A01N43/60 ,  A01N43/653 ,  A01N43/66 ,  A01N43/74 ,  A01N43/90 ,  A01N47/20 ,  A01N57/24 ,  B01J23/10 ,  B01J23/12 ,  B01J23/20 ,  B01J23/24 ,  B01J23/32 ,  B01J23/38 ,  B01J23/72 ,  B01J27/10 ,  C07B61/00 ,  C07C45/59 ,  C07C67/00 ,  C07C67/31 ,  C07C69/734 ,  C07C201/00 ,  C07C201/12 ,  C07C205/35 ,  C07C205/37 ,  C07C205/38 ,  C07C205/52 ,  C07C205/56 ,  C07C217/92 ,  C07C233/25 ,  C07C233/75 ,  C07C235/56 ,  C07C245/08 ,  C07C251/24 ,  C07C251/48 ,  C07C255/54 ,  C07C271/28 ,  C07C311/29 ,  C07C317/22 ,  C07C323/20 ,  C07C327/16 ,  C07D207/34 ,  C07D213/64 ,  C07D213/643 ,  C07D213/65 ,  C07D213/68 ,  C07D213/74 ,  C07D213/85 ,  C07D213/89 ,  C07D215/22 ,  C07D215/227 ,  C07D215/36 ,  C07D237/14 ,  C07D239/34 ,  C07D239/38 ,  C07D239/60 ,  C07D241/18 ,  C07D241/44 ,  C07D251/26 ,  C07D263/58 ,  C07D277/24 ,  C07D277/68 ,  C07D333/56 ,  C07D495/04 ,  C07D521/00 ,  C07F9/54

CPC classification number: C07D213/64 ,  A01N37/38 ,  A01N37/40 ,  A01N41/04 ,  A01N41/06 ,  A01N41/10 ,  A01N43/10 ,  A01N43/20 ,  A01N43/36 ,  A01N43/40 ,  A01N43/42 ,  A01N43/54 ,  A01N43/58 ,  A01N43/60 ,  A01N43/653 ,  A01N43/66 ,  A01N43/74 ,  A01N43/90 ,  A01N47/20 ,  A01N57/24 ,  C07C201/12 ,  C07C45/59 ,  C07C67/31 ,  C07D207/34 ,  C07D213/643 ,  C07D213/65 ,  C07D213/68 ,  C07D213/74 ,  C07D213/85 ,  C07D213/89 ,  C07D215/227 ,  C07D215/36 ,  C07D231/12 ,  C07D233/56 ,  C07D237/14 ,  C07D239/34 ,  C07D239/38 ,  C07D239/60 ,  C07D241/18 ,  C07D241/44 ,  C07D249/08 ,  C07D251/26 ,  C07D263/58 ,  C07D277/24 ,  C07D277/68 ,  C07D333/56 ,  C07D495/04 ,  C07F9/5456

Abstract: Process for the preparation of a compound of general formula (I): ##STR1## by reacting a compound of general formula (II) ##STR2## (X is halide; rings M and N are optionally substituted) with an optionally substituted phenol in the presence of a base, or with an optionally substituted phenolate salt; preferably in the presence of a catalyst which is a transition metal, a transition metal salt or compound or a mixture thereof.

公开(公告)号：US4929772A

公开(公告)日：1990-05-29

申请号：US321171

申请日：1989-03-09

Applicant: Pietro Massardo ,  Franco Bettarini ,  Paolo Piccardi ,  Franco Rama

Inventor： Pietro Massardo ,  Franco Bettarini ,  Paolo Piccardi ,  Franco Rama

IPC: B01J23/00 ,  B01J27/00 ,  C07B31/00 ,  C07B41/02 ,  C07B61/00 ,  C07C27/00 ,  C07C29/64 ,  C07C41/30 ,  C07C43/23 ,  C07C45/00 ,  C07C45/68 ,  C07C47/195 ,  C07C47/273 ,  C07C47/56 ,  C07C49/82 ,  C07C51/367 ,  C07C67/00 ,  C07C69/675 ,  C07C69/757 ,  C07C201/00 ,  C07C205/26 ,  C07C205/58 ,  C07C213/00 ,  C07C215/68 ,  C07C253/00 ,  C07C255/53 ,  C07C313/00 ,  C07C319/20 ,  C07C323/12 ,  C07D213/30 ,  C07D307/42 ,  C07D333/16

CPC classification number: C07D213/30 ,  C07C205/26 ,  C07C29/64 ,  C07C37/20 ,  C07C41/30 ,  C07C45/68 ,  C07C47/195 ,  C07C47/56 ,  C07C67/343 ,  C07D307/42 ,  C07D333/16

Abstract: There is disclosed a process for preparing polyhalogenated carbinols having formula: ##STR1## by reacting a compound having formula: ##STR2## with a system consisting of a compound having formula: ##STR3## and of a divalent metal or of a metal salt, in protic dipolar solvents, in which formulaeR=H, an alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkadienyl, phenyl, naphthyl, anthracyl group, a heterocyclic radical, optionally substituted;R'=H, a haloalkyl, --CN, --COOR" group with R" equal to H or to an alkyl group;X.sup.1 =Cl, Br; =X.sub.2 =F, Cl, Br;X.sup.3 =Cl, Br, CF.sub.3, CCl.sub.3 ; Y=Br or Cl when X.sup.1, X.sup.2 and X.sup.3 are different from Br.

Abstract translation: 公开了一种制备具有下式的多卤代甲醇的方法：通过使具有下式的化合物：（II）与具有下列化学式的化合物：（IMA）（III）和式 二价金属或金属盐，在质子偶极溶剂中，其中式R = H，烷基，环烷基，烯基，环烯基，链二烯基，苯基，萘基，蒽基，杂环基，任选取代; R'= H，R“等于H的卤代烷基，-CN，-COOR”基团或烷基; X1 = Cl，Br; = X2 = F，Cl，Br; X3 = Cl，Br，CF3，CCl3; 当X1，X2和X3与Br不同时，Y = Br或Cl。

公开(公告)号：US4929710A

公开(公告)日：1990-05-29

申请号：US105799

申请日：1987-10-07

Applicant: Thomas Scholl ,  Gert Jabs ,  Adolf Richartz

Inventor： Thomas Scholl ,  Gert Jabs ,  Adolf Richartz

IPC: B41M5/333 ,  B41M5/155 ,  C07C65/105 ,  C07C65/24 ,  C07C67/00 ,  C07C69/035 ,  C07C69/773 ,  C07C201/00 ,  C07C205/59 ,  C07C253/00 ,  C07C255/57 ,  C08G61/00 ,  C08G61/02

CPC classification number: B41M5/155 ,  C07C65/105

Abstract: Hydroxycarboxylic acid derivatives of the formula ##STR1## are particularly suitable for use as color developers in recording materials.

Abstract translation: 具有式（I）的羟基羧酸衍生物特别适合用作记录材料中的显色剂。

公开(公告)号：US4906770A

公开(公告)日：1990-03-06

申请号：US246619

申请日：1988-09-20

Applicant: Giuseppe Marchionni ,  Anna Staccione

Inventor： Giuseppe Marchionni ,  Anna Staccione

IPC: C07C43/313 ,  C07C67/00 ,  C07C71/00 ,  C07C201/00 ,  C08G65/00 ,  C08G65/323

CPC classification number: C08G65/3236 ,  C08G65/007

Abstract: Mono- or difunctional perfluoropolyethers with hypofluorite end groups, and a process for preparing them which comprises reacting a perfluoropolyether having at least one fluoroformate end group, or containing a peroxy group --O--CF.sub.2 OO--CF.sub.2 --O--, with fluorine in the liquid phase at a temperature ranging from -60.degree. C. to 30.degree. C., in the presence of UV radiation of a wave-length ranging from 200 to 500 nm.

公开(公告)号：US4900846A

公开(公告)日：1990-02-13

申请号：US113153

申请日：1987-10-27

Applicant: Gregory P. Harris

Inventor： Gregory P. Harris

IPC: C07D319/06 ,  C07C45/59 ,  C07C47/27 ,  C07C47/273 ,  C07C47/277 ,  C07C51/00 ,  C07C51/353 ,  C07C59/48 ,  C07C59/52 ,  C07C59/56 ,  C07C59/64 ,  C07C67/00 ,  C07C69/035 ,  C07C201/00 ,  C07C205/56 ,  C07C231/00 ,  C07C231/12 ,  C07C233/18 ,  C07C233/25 ,  C07C233/33 ,  C07C301/00 ,  C07C303/40 ,  C07C311/03 ,  C07C311/51 ,  C07D307/20 ,  C07D307/33 ,  C07D319/08

CPC classification number: C07D307/33 ,  C07C59/64 ,  C07D307/20 ,  C07D319/08

Abstract: The invention provides a novel process for making novel (4-phenyl-1,3-dioxan-cis-5-yl)alkenoic acids of the formula I in which Ra and Rb are independently hydrogen, alkenyl, alkyl, halogenoalkyl, pentafluorophenyl, aryl or aryl-(1,4C)alkyl; or Ra and Rb together are polymethylene; Rc is hydroxy or (1-6C)alkanesulphonamideo, A is vinylene, n is 1, Y is polymethylene, and benzene ring B bears various optional substituents. The process involves the reaction of an aldehyde of formula II with an ylid to give an erythro-diol of formula III which is then cyclized to the required dioxane derivative of formula I. The invention also provides a novel process for making the aldehydes of formula II from the corresponding lactols of formula IIa, which are themselves obtained with the correct trans-stereochemistry by two selective reductions of a trans-phenylparaconic acid of formula V. The compounds of formula I are useful as thereapeutic agents.

公开(公告)号：US4898877A

公开(公告)日：1990-02-06

申请号：US157678

申请日：1988-02-18

Applicant: Horst Meyer ,  Eckhard Schwenner ,  Martin Bechem ,  Rainer Gross ,  Matthias Schramm ,  Michael Kayser ,  Siegbert Hebisch

Inventor： Horst Meyer ,  Eckhard Schwenner ,  Martin Bechem ,  Rainer Gross ,  Matthias Schramm ,  Michael Kayser ,  Siegbert Hebisch

IPC: C07D213/30 ,  A61K31/215 ,  A61K31/23 ,  A61K31/235 ,  A61K31/275 ,  A61K31/33 ,  A61K31/395 ,  A61K31/40 ,  A61K31/44 ,  A61P3/08 ,  A61P9/00 ,  A61P9/06 ,  C07C67/00 ,  C07C69/757 ,  C07C201/00 ,  C07C205/55 ,  C07C205/56 ,  C07C227/00 ,  C07C227/16 ,  C07C229/48 ,  C07C235/40 ,  C07C253/00 ,  C07C255/45 ,  C07C255/46 ,  C07C311/12 ,  C07C311/15 ,  C07C311/19 ,  C07C311/20 ,  C07C313/00 ,  C07C315/04 ,  C07C317/14 ,  C07C317/18 ,  C07C317/22 ,  C07C317/46 ,  C07C323/12 ,  C07C323/62 ,  C07C323/65 ,  C07C323/67 ,  C07D295/22

CPC classification number: C07C255/00 ,  C07C205/56 ,  C07C309/00 ,  C07C317/00

Abstract: Novel circulation-active cyclohexenecarboxylates of the formula ##STR1## in which R.sup.1 is an organic radical,R.sup.2 is an optionally substituted aryl radical,R.sup.3 is an optionally substituted alkyl or aryl radical,X and Y are --CN, --COR.sup.4, --SO.sub.2 R.sup.4, --COOR.sup.5, --CONR.sup.6 R.sup.7 or --SO.sub.2 NR.sup.6 R.sup.7, andR.sup.4, R.sup.5, R.sup.6 and R.sup.7 are various organic radicals.

Abstract translation: 式（I）的新型循环活性环己烯羧酸酯，其中R 1是有机基团，R 2是任选取代的芳基，R 3是任选取代的烷基或芳基，X和Y是-CN，-COR 4， -SO 2 R 4，-COOR 5，-CONR 6 R 7或-SO 2 NR 6 R 7，R4，R5，R6和R7是各种有机基团。

公开(公告)号：US4892686A

公开(公告)日：1990-01-09

申请号：US275238

申请日：1988-11-22

Applicant: Walter Fischer ,  Tibor Somlo

Inventor： Walter Fischer ,  Tibor Somlo

IPC: B01J21/02 ,  B01J27/236 ,  B01J31/04 ,  C07B61/00 ,  C07C67/00 ,  C07C201/00 ,  C07C201/12 ,  C07C205/47

CPC classification number: C07C205/47 ,  C07C201/12 ,  C07C201/16 ,  C07C2103/24

Abstract: A process for the preparation of 1-nitroanthraquinone by oxidising 1-nitro-5,8,11,12-tetrahydroanthraquinone with oxygen, inorganic peroxo compounds or metal oxides.

Abstract translation: 通过用氧，无机过氧化合物或金属氧化物氧化1-硝基-5,8,11,12-四氢蒽醌来制备1-硝基蒽醌的方法。

公开(公告)号：US4879401A

公开(公告)日：1989-11-07

申请号：US102370

申请日：1987-09-29

Applicant: Arthur R. Doumaux, Jr. ,  James R. Nelson

Inventor： Arthur R. Doumaux, Jr. ,  James R. Nelson

IPC: C07C201/16 ,  C07C67/00 ,  C07C201/00 ,  C07C201/04 ,  C07C203/00 ,  C07C203/02 ,  C07C203/04

CPC classification number: C07C201/04

Abstract: A process is provided for removing impurities from the gaseous product of an alkyl nitrite production zone by contacting a portion of it with lower alcohol and oxygen to convert substantially all of the nitric oxide in that portion of the gaseous product stream to alkyl nitrite, the oxygen being present in an amount such that the mole ratio of nitric oxide to oxygen is in the range of about 4:1 to about 2:1 and the lower alcohol being present in the reaction zone such that the mole ratio of nitric oxide to lower alcohol is about 1:1 or less. A recovery stream, comprising alkyl nitrite substantially free of nitric oxide, is withdrawn from the reaction zone and at least a portion of the alkyl produced in the reaction zone is removed. A least a portion of the balance of the recovery stream from which the alkyl nitrite has been removed is purged, thereby removing impurities from the process.

Abstract translation: 提供了一种通过使其一部分与低级醇和氧接触而从亚硝酸烷基酯生产区的气态产物中除去杂质的方法，以将该部分气态产物流中的所有一氧化氮转化为亚硝酸烷基酯，氧气 存在的量使得一氧化氮与氧的摩尔比在约4:1至约2:1的范围内，低级醇存在于反应区中，使得一氧化氮与低级醇的摩尔比 约为1：1或更少。 包含基本上不含一氧化氮的亚硝酸烷基酯的回收流从反应区中排出，并且除去反应区中产生的烷基的至少一部分。 将亚硝酸烷基酯从其中除去的回收料流的余量的至少一部分被清除，从而从该方法中除去杂质。

公开(公告)号：US4876376A

公开(公告)日：1989-10-24

申请号：US134539

申请日：1987-12-15

Applicant: Michael Desbois ,  Camille Disdier

Inventor： Michael Desbois ,  Camille Disdier

IPC: C07B39/00 ,  C07B31/00 ,  C07B43/02 ,  C07C67/00 ,  C07C201/00 ,  C07C201/14 ,  C07C205/11 ,  C07C205/12 ,  C07C205/37 ,  C07C205/38 ,  C07C205/58 ,  C07C231/00 ,  C07C231/12 ,  C07C239/00 ,  C07C241/00 ,  C07C253/00 ,  C07C255/50 ,  C07C265/12 ,  C07C271/00 ,  C07C271/04 ,  C07C313/00 ,  C07C319/20 ,  C07C323/09 ,  C07C323/43

CPC classification number: C07C201/08 ,  C07C269/02

Abstract: A process for the halogenation (bromination or chlorination)/nitration/fluorination of aromatic derivatives substituted by at least one group containing a halogenoalkyl unit. The aromatic derivative is reacted with a halogen and a nitrating agent in liquid hydrofluoric acid. The products obtained are useful as intermediates for the synthesis of compounds having a plant-protecting or pharmaceutical activity.

Abstract translation: 由至少一个含有卤代烷基单元的基团取代的芳族衍生物的卤化（溴化或氯化）/硝化/氟化的方法。 芳族衍生物与液态氢氟酸中的卤素和硝化剂反应。 获得的产物可用作合成具有植物保护或药物活性的化合物的中间体。