公开(公告)号：DE69729106T2

公开(公告)日：2005-05-12

申请号：DE69729106

申请日：1997-09-19

Applicant: ARNOLD LEE

Inventor： ARNOLD LEE

IPC: F03B13/20 ,  F03B17/00 ,  F03B17/06 ,  F03D5/00 ,  F03D5/06

Abstract: Method and apparatus for converting the kinetic energy of a moving fluid stream into useful work by using a cascade of thin aero or hydro foils positioned therein. The foils may be provided with at least two degrees of freedom and adjacent foils move out of phase. The foils are subjected to fluid induced oscillations known as flutter. Barriers (3, 43) may be positioned upstream, above, or at sides of the apparatus for increasing efficiency by increasing the fluid velocity. A system of flywheels (17, 18) are used to increase inertia of the foils and are particularly useful with hydrofoils. A cascade of aero or hydro foils may be mechanically oscillated to transfer energy to a fluid.

公开(公告)号：AT266811T

公开(公告)日：2004-05-15

申请号：AT97944374

申请日：1997-09-19

Applicant: ARNOLD LEE

Inventor： ARNOLD LEE

IPC: F03B13/20 ,  F03B17/00 ,  F03B17/06 ,  F03D5/00 ,  F03D5/06

Abstract: Method and apparatus for converting the kinetic energy of a moving fluid stream into useful work by using a cascade of thin aero or hydro foils positioned therein. The foils may be provided with at least two degrees of freedom and adjacent foils move out of phase. The foils are subjected to fluid induced oscillations known as flutter. Barriers (3, 43) may be positioned upstream, above, or at sides of the apparatus for increasing efficiency by increasing the fluid velocity. A system of flywheels (17, 18) are used to increase inertia of the foils and are particularly useful with hydrofoils. A cascade of aero or hydro foils may be mechanically oscillated to transfer energy to a fluid.

公开(公告)号：IL258124D0

公开(公告)日：2018-05-31

申请号：IL25812418

申请日：2018-03-14

Applicant: ASSEMBLY BIOSCIENCES INC ,  UNIV INDIANA RES & TECH CORP ,  TURNER WILLIAM ,  MAAG HANS ,  ARNOLD LEE DANIEL ,  LI LEPING ,  BURES MARK ,  HAYDAR SIMON ,  FRANCIS SAMSON

Inventor： TURNER WILLIAM ,  MAAG HANS ,  ARNOLD LEE DANIEL ,  LI LEPING ,  BURES MARK ,  HAYDAR SIMON ,  FRANCIS SAMSON

IPC: A61K20060101

Abstract: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

公开(公告)号：IL258099D0

公开(公告)日：2018-05-31

申请号：IL25809918

申请日：2018-03-13

Applicant: ASSEMBLY BIOSCIENCES INC ,  UNIV INDIANA RES & TECH CORP ,  TURNER WILLIAM ,  MAAG HANS ,  ARNOLD LEE DANIEL ,  BURES MARK

Inventor： TURNER WILLIAM ,  MAAG HANS ,  ARNOLD LEE DANIEL ,  BURES MARK

IPC: A61K20060101

Abstract: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

公开(公告)号：CA2266632C

公开(公告)日：2004-03-09

申请号：CA2266632

申请日：1997-09-19

Applicant: ARNOLD LEE

Inventor： ARNOLD LEE

IPC: F03B13/20 ,  F03B17/00 ,  F03B17/06 ,  F03D5/00 ,  F03D5/06

Abstract: Method and apparatus for converting the kinetic energy of a moving fluid stream into useful work by using a cascade of thin aero of hydro foils (2) positioned therein. The foils may be provided with at least two degrees of freedom and adjacent foils move out of phase. The foils are subjected to fluid induced oscillations known as flutter. Barriers (3, 43) may be positioned downstream, above, or at the sides of the apparatus for increasing efficiency. A system of fly wheels (17, 18) to increase inertia of the foils may be used with the hydrofoils. A cascade of aero of hydro foils may be mechanically oscillated.

公开(公告)号：IL129049A

公开(公告)日：2002-05-23

申请号：IL12904997

申请日：1997-09-19

Applicant: ARNOLD LEE

IPC: F03B13/20 ,  F03B17/00 ,  F03B17/06 ,  F03D5/00 ,  F03D5/06

Abstract: Method and apparatus for converting the kinetic energy of a moving fluid stream into useful work by using a cascade of thin aero or hydro foils positioned therein. The foils may be provided with at least two degrees of freedom and adjacent foils move out of phase. The foils are subjected to fluid induced oscillations known as flutter. Barriers (3, 43) may be positioned upstream, above, or at sides of the apparatus for increasing efficiency by increasing the fluid velocity. A system of flywheels (17, 18) are used to increase inertia of the foils and are particularly useful with hydrofoils. A cascade of aero or hydro foils may be mechanically oscillated to transfer energy to a fluid.

公开(公告)号：AU4588497A

公开(公告)日：1998-04-14

申请号：AU4588497

申请日：1997-09-19

Applicant: ARNOLD LEE

Inventor： ARNOLD LEE

IPC: F03B13/20 ,  F03B17/00 ,  F03B17/06 ,  F03D5/00 ,  F03D5/06

Abstract: Method and apparatus for converting the kinetic energy of a moving fluid stream into useful work by using a cascade of thin aero or hydro foils positioned therein. The foils may be provided with at least two degrees of freedom and adjacent foils move out of phase. The foils are subjected to fluid induced oscillations known as flutter. Barriers (3, 43) may be positioned upstream, above, or at sides of the apparatus for increasing efficiency by increasing the fluid velocity. A system of flywheels (17, 18) are used to increase inertia of the foils and are particularly useful with hydrofoils. A cascade of aero or hydro foils may be mechanically oscillated to transfer energy to a fluid.

公开(公告)号：IL269037D0

公开(公告)日：2019-10-31

申请号：IL26903719

申请日：2019-09-01

Applicant: ASSEMBLY BIOSCIENCES INC ,  ARNOLD LEE DANIEL ,  FRANCIS SAMSON ,  TURNER WILLIAM W JR ,  HAYDAR SIMON NICOLAS ,  BURES MARK G ,  RAI ROOPA ,  LI LEPING

Inventor： ARNOLD LEE DANIEL ,  FRANCIS SAMSON ,  TURNER WILLIAM W JR ,  HAYDAR SIMON NICOLAS ,  BURES MARK G ,  RAI ROOPA ,  LI LEPING

IPC: C07D20060101

Abstract: The present disclosure provides, in part, cyclic sulfamide compounds, and pharmaceutical compositions thereof, useful as modulators of Hepatitis B (HBV) core protein, and methods of treating Hepatitis B (HBV) infection.

公开(公告)号：CA1132436A

公开(公告)日：1982-09-28

申请号：CA341760

申请日：1979-12-12

Applicant: ARNOLD LEE

Inventor： ARNOLD LEE

IPC: F03D5/06

Abstract: There is disclosed a method and apparatus for converting the kinetic energy of a moving fluid stream into useful work by means of a cascade of thin airfoils positioned therein. In one embodiment, the airfoils are provided with at least two degrees of freedom and adjacent airfoils are movable out of phase. The airfoils are subjected to the aerodynamically induced oscillations caused by the aeroelastic phenomenon known as flutter and the oscillatory movement is then harnessed to do useful work. In an alternate embodiment, a cascade of airfoils is mechanically oscillated within a moving fluid stream to increase the propulsion of the fluid. Where the fluid is a liquid, the cascade includes a plurality of hydrofoils.

公开(公告)号：WO2013033268A3

公开(公告)日：2013-03-07

申请号：PCT/US2012/052941

申请日：2012-08-29

Applicant: COFERON, INC. ,  ARNOLD, Lee, Daniel ,  FOREMAN, Kenneth, W. ,  WERNER, Douglas, S.

Inventor： ARNOLD, Lee, Daniel ,  FOREMAN, Kenneth, W. ,  WERNER, Douglas, S.

IPC: C07D487/04 ,  C07D413/12 ,  C07D519/00 ,  A61K31/55 ,  A61P35/00

Abstract: Described herein are compounds of formula capable of modulating one or more biomolecules substantially simultaneously, e.g., modulating two or more binding domains (e.g., bro-modomains) on a protein or on different proteins.