公开(公告)号：WO1998019293A1

公开(公告)日：1998-05-07

申请号：PCT/US1997008153

申请日：1997-05-12

Applicant: APPLIED SPECTRAL IMAGING (ASI) LTD. ,  CABIB, Dario ,  BUCKWALD, Robert, A.

Inventor： APPLIED SPECTRAL IMAGING (ASI) LTD.

IPC: G10B09/02

CPC classification number: G01J3/45

Abstract: A method for spatial registration and spectral correction for interferometer based spectral imaging which can be used to obtain spectral images of a moving object, the method comprising the steps of (a) using an interferometer based spectral imager for acquiring spatial and spectral information of the moving object; and (b) correcting the spatial and spectral information for movements of the moving object via a spatial registration and spectral correction procedures for obtaining corrected spatial and spectral information.

Abstract translation: 一种用于基于干涉仪的光谱成像的空间配准和光谱校正方法，其可用于获得移动物体的光谱图像，所述方法包括以下步骤：（a）使用基于干涉仪的光谱成像器来获取移动的空间和光谱信息 目的; 以及（b）经由用于获得校正的空间和频谱信息的空间配准和频谱校正程序来校正用于移动物体的移动的空间和频谱信息。

公开(公告)号：WO1997022848A1

公开(公告)日：1997-06-26

申请号：PCT/US1996020022

申请日：1996-12-10

Applicant: SPECTRAL DIAGNOSTIC LTD. ,  GARINI, Yuval ,  CABIB, Dario ,  BUCKWALD, Robert, A. ,  SOENKSEN, Dirk, G. ,  KATZIR, Nir ,  WINE, David ,  LAVI, Moshe

Inventor： SPECTRAL DIAGNOSTIC LTD.

IPC: G01B09/02

CPC classification number: G01N21/6458 ,  A61B3/12 ,  A61B3/1241 ,  C12Q1/6816 ,  C12Q1/6841 ,  C12Q1/6883 ,  C12Q2600/156 ,  G01B11/0675 ,  G01J3/02 ,  G01J3/12 ,  G01J3/1256 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/4406 ,  G01J3/453 ,  G01J3/4535 ,  G01J2003/2866 ,  G01N21/6428 ,  G01N33/5005 ,  G01N33/56966 ,  G01N33/582 ,  G01N2021/6417 ,  G01N2021/6441 ,  G06K9/00127 ,  G06K9/76

Abstract: A spectral imaging method for detecting and analyzing fluorescent in situ hybridizations (fig. 5) employing numerous chromosome paints (fig. 9) and/or loci specific probes each labeled with a different fluorophore or a combination of fluorophores, the method is highly sensitive both in spatial and spectral resolutions (fig. 6) and is capable of simultaneous detection of dozens of fluorophores or combinations of fluorophores (fig. 7). The method of the present invention can be used for the detection of fluorescently painted complete sets of chromosomes and/or multiple loci from a species such as human (fig. 10).

Abstract translation: 用于检测和分析荧光原位杂交（图5）的光谱成像方法，其使用多种染色体涂料（图9）和/或每个用不同的荧光团或荧光团的组合标记的基因座特异性探针，该方法是高度敏感的 在空间和光谱分辨率（图6）中并且能够同时检测数十个荧光团或荧光团的组合（图7）。 本发明的方法可用于检测来自人类的物种的荧光涂覆的成套染色体和/或多个基因座（图10）。

公开(公告)号：WO1997021979A1

公开(公告)日：1997-06-19

申请号：PCT/US1996020024

申请日：1996-12-10

Applicant: SPECTRAL DIAGNOSTIC LTD. ,  GARINI, Yuval ,  KATZIR, Nir ,  SOENKSEN, Dirk, G. ,  CABIB, Dario ,  BUCKWALD, Robert, A. ,  MALIK, Zvi

Inventor： SPECTRAL DIAGNOSTIC LTD.

IPC: G01B09/02

CPC classification number: G01N21/6458 ,  C12Q1/6841 ,  C12Q1/6883 ,  G01J3/02 ,  G01J3/12 ,  G01J3/1256 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/4406 ,  G01J3/453 ,  G01J2003/2866 ,  G01N21/6428 ,  G01N21/6486 ,  G01N33/5005 ,  G01N33/56966 ,  G01N33/582 ,  G01N2021/6417 ,  G01N2021/6423 ,  G06K9/00127 ,  G06K9/76 ,  C12Q2563/173 ,  C12Q2563/131 ,  C12Q2563/107

Abstract: Spectral imaging methods (fig. 2) for biological research, medical diagnostics and therapy to be used to detect spatial organization and to quantify cellular (fig. 5) and tissue natural constituents, structures, organelles and administered components such as tagging probes (fig. 27) and drugs using light transmission (fig. 9), reflection, scattering and fluorescence emission strategies (fig. 7), with high sensitivity and high spatial and spectral resolutions.

Abstract translation: 用于生物研究，医学诊断和治疗的光谱成像方法（图2）用于检测空间组织和量化细胞（图5）和组织天然成分，结构，细胞器和施用组分，如标记探针（图2）。 27）和使用光透射的药物（图9），反射，散射和荧光发射策略（图7），具有高灵敏度和高空间和光谱分辨率。

公开(公告)号：IL261164A

公开(公告)日：2021-08-31

申请号：IL26116418

申请日：2018-08-15

Applicant: CI SYSTEMS ISRAEL LTD ,  CABIB DARIO

Inventor： CABIB DARIO

IPC: G01J3/02 ,  G01J3/26 ,  G01J3/42 ,  G01J3/427 ,  G01J3/433 ,  G01J3/45 ,  G01J3/453 ,  G02B27/50

Abstract: An interference fringe pattern generator forms an interference fringe pattern from the light rays diffused from a region of an object positioned against a background. A planar array of detector pixels is arranged to capture an image of the interference fringe pattern. A storage medium records information indicative of intensity values of the image of the interference fringe pattern captured by a selected group of pixels of the planar array of detector pixels. The information is recorded as a function of the optical path difference values traversed by the diffused light rays through the interference fringe pattern generator for each of the pixels in the selected group of pixels. A processor determines the spectral characteristics of the object based on the information indicative of the intensity values recorded by the storage medium and the optical path difference values traversed by the diffused light rays.

公开(公告)号：IL253477D0

公开(公告)日：2017-09-28

申请号：IL25347717

申请日：2017-07-13

Applicant: CI SYSTEMS ISRAEL LTD ,  CABIB DARIO ,  LAVI MOSHE ,  GIL AMIR ,  SINGHER LIVIU

Inventor： CABIB DARIO ,  LAVI MOSHE ,  GIL AMIR ,  SINGHER LIVIU

IPC: G01J20060101

Abstract: Disclosed are devices (100-2, 100-4) imaging radiation from a scene that includes two materials with spectral characteristics in two different wavelength regions. A lens (9) forms an image of the scene on a part (1a) of detector (1) that includes an array pixels. A blackbody source (60) positioned within the device housing (30) illuminates a separate part (1b) of the detector that does not receive radiation from the scene . The corresponding signal is used to correct the pixel signals produced from the scene radiation.

公开(公告)号：IL261129D0

公开(公告)日：2018-10-31

申请号：IL26112918

申请日：2018-08-13

Applicant: TECHNION RES & DEV FOUNDATION ,  CI SYSTEMS ISRAEL LTD ,  CABIB DARIO ,  GIL AMIR ,  ROTSCHILD CARMEL ,  WOLOWELSKY KARNI

Inventor： CABIB DARIO ,  GIL AMIR ,  ROTSCHILD CARMEL ,  WOLOWELSKY KARNI

IPC: G01N20060101

公开(公告)号：IL256365D0

公开(公告)日：2018-02-28

申请号：IL25636517

申请日：2017-12-17

Applicant: CI SYSTEMS ISRAEL LTD ,  CABIB DARIO

Inventor： CABIB DARIO

IPC: G01C20060101

Abstract: A system analyzes radiation from a scene in a field of view that includes a gas cloud with absorption characteristics in a wavelength band. The system includes first and second devices. The first device includes a detector and produces pixel signals that include information associated with absorption of radiation in the gas cloud wavelength band. An image of the scene is formed on the detector based on the pixel signals. A non-predetermined region of the scene within the field of view in which the gas cloud is present is identified based on the pixel signals. The second device includes a detector and a lens, and receives the identified region of the scene. The system determines a distance between the identified region of the scene and the system based on the lens focus relative to the identified region of the scene in an image formed on the detector by the lens.

公开(公告)号：IL253477B2

公开(公告)日：2023-08-01

申请号：IL25347717

申请日：2017-07-13

Applicant: CI SYSTEMS ISRAEL LTD ,  CABIB DARIO ,  LAVI MOSHE ,  GIL AMIR ,  SINGHER LIVIU

Inventor： CABIB DARIO ,  LAVI MOSHE ,  GIL AMIR ,  SINGHER LIVIU

IPC: G01N21/17 ,  G01N21/27 ,  G01N21/31 ,  G01N21/3504

Abstract: Disclosed are devices (100-2, 100-4) imaging radiation from a scene that includes two materials with spectral characteristics in two different wavelength regions. A lens (9) forms an image of the scene on a part (1a) of detector (1) that includes an array pixels. A blackbody source (60) positioned within the device housing (30) illuminates a separate part (1b) of the detector that does not receive radiation from the scene . The corresponding signal is used to correct the pixel signals produced from the scene radiation.

公开(公告)号：IL261164D0

公开(公告)日：2018-10-31

申请号：IL26116418

申请日：2018-08-15

Applicant: CI SYSTEMS ISRAEL LTD ,  CABIB DARIO

Inventor： CABIB DARIO

IPC: G01J20060101

Abstract: An interference fringe pattern generator forms an interference fringe pattern from the light rays diffused from a region of an object positioned against a background. A planar array of detector pixels is arranged to capture an image of the interference fringe pattern. A storage medium records information indicative of intensity values of the image of the interference fringe pattern captured by a selected group of pixels of the planar array of detector pixels. The information is recorded as a function of the optical path difference values traversed by the diffused light rays through the interference fringe pattern generator for each of the pixels in the selected group of pixels. A processor determines the spectral characteristics of the object based on the information indicative of the intensity values recorded by the storage medium and the optical path difference values traversed by the diffused light rays.

公开(公告)号：IL288736B1

公开(公告)日：2025-03-01

申请号：IL28873621

申请日：2021-12-06

Applicant: C I SYSTEMS LTD ,  C I SYSTEMS ISRAEL LTD ,  LAVI MOSHE ,  CABIB DARIO

Inventor： LAVI MOSHE ,  CABIB DARIO

IPC: G02B27/09 ,  G02B27/12 ,  G02B27/42

Abstract: An optical device includes two prisms and a beamsplitter configuration. A first of the prisms has a first surface associated with a source and a second surface oblique to the first surface. A second of the prisms has a first surface associated with a detector and a second surface oblique to the first surface. The second surface of the first prism overlaps with the second surface of the second prism to define an interface region that partially extends along at least one of the second surfaces. The prisms are optically attached at the interface region, and the beamsplitter configuration overlies the interface region. A beam emitted by the source propagates through the prisms along two optical paths and reaches the detector as two coherent beams. Beams that propagate along the two optical paths are reflected from the beamsplitter configuration and transmitted by the beamsplitter configuration exactly once.