-
11.发明申请
公开(公告)号：WO2002086465A1
公开(公告)日：2002-10-31
申请号：PCT/US2002/011084
申请日：2002-04-08
Applicant: DADE MICROSCAN INC.
Inventor： FARINA, Edward, Francis , GEMMELL, Bruce, McLean , MAZZA, John, Charles , MCVEY, Michael, Taylor , KAMINSKI, Edward, Stephen , HADDAD, Antoine, Elias , GEBRIAN, Peter, Louis
IPC: G01N21/00
CPC classification number: B01L3/5085 , B01L7/00 , C12M41/36 , C12M41/48 , G01N35/025 , G01N2035/00148 , G01N2035/1076
Abstract: A circular shaped rotor (16) to facilitate automated identification testing of microorganisms in a microbiology analyzer (10) having two circular arrays (120,124) of microwells downwardly projecting from the top of the rotor (16) connected to a recessed central region (114) by a plurality of microchannels (118,122) formed in the upper surface and connecting the recessed central portion to the second plurality of microwells; the rotor is further adapted to be rotated by a source of rotational energy and moved throughout the analyzer using troughs (126) formed near its outer diameter.
Abstract translation: 一种圆形转子（16），用于在微生物学分析仪（10）中有助于微生物分析仪（10）的自动识别测试，所述微生物学分析仪具有从连接到凹入的中心区域（114）的转子（16）的顶部向下突出的微孔的两个圆形阵列（120,124） 通过形成在上表面中的多个微通道（118,122）并将凹入的中心部分连接到第二多个微孔; 转子还适于通过旋转能量源旋转并且通过在其外径附近形成的槽（126）移动到整个分析器中。
-
12.发明申请METHOD AND APPARATUS FOR MIXING LIQUID SAMPLES IN A CONTAINER USING ROTATING MAGNETIC FIELDS 审中-公开使用旋转磁场在集装箱中混合液体样品的方法和装置
公开(公告)号：WO2002085505A1
公开(公告)日：2002-10-31
申请号：PCT/US2002/011085
申请日：2002-04-08
Applicant: DADE MICROSCAN INC.
Inventor： GEBRIAN, Peter, Louis
IPC: B01F13/08
CPC classification number: B01F7/005 , B01F13/0818 , B01F2215/0037
Abstract: Mixing a liquid solution (18) in a container (14) by revolving a pair of magnets (12) in close proximity to and on opposite sides of the container a distance above the bottom of the container causing a magnetic mixing member (16) to rotate in the liquid about the same distance above the bottom of the container.
Abstract translation: 将容器（14）中的液体溶液（18）通过使一对磁体（12）在集装箱的底部附近旋转一个距离容器底部一定距离的位置，使一个磁性混合件（16）至 在容器底部相同的距离上旋转液体。
-
公开(公告)号：WO2002068581A1
公开(公告)日：2002-09-06
申请号：PCT/US2002/006112
申请日：2002-02-28
Applicant: DADE MICROSCAN INC.
Inventor： FARINA, Edward, Francis , FERGUSON, Samuel, Garfield, Jr. , GEBRIAN, Peter, Louis , KRUFKA, Frank, Stephen , MAZZA, John, Charles , SHMEL, Nicholas, Michael, Jr.
IPC: C12M1/34
CPC classification number: B01L3/502707 , B01L3/502723 , B01L2200/0684 , B01L2200/142 , B01L2300/0864 , B01L2400/049
Abstract: A microbiological test array (12) with a generally flat base (11) having a plurality of upwardly projecting microwells (44) connected by a microchannel (42) to an open reservoir (50) formed in a top surface (13) generally parallel to the base (11) of the test array (12). The reservoir (50) has an opening to permit an inoculum-broth liquid solution to flow from the reservoir through the microchannel (51), to a sacrificial evaporation well (46) having an air vent port (48) adapted to control a vacuum filling process, and subsequently to be distributed into each of the plurality of microwells (44).
Abstract translation: 具有大致平坦的基部（11）的微生物测试阵列（12）具有多个向上突出的微孔（44），所述多个向上突出的微孔（44）通过微通道（42）连接到形成在顶表面（13）中的大致平行于 测试阵列（12）的基座（11）。 储存器（50）具有开口以允许接种物液体溶液从储存器流过微通道（51）到具有适于控制真空填充物的排气口（48）的牺牲蒸发井（46） 过程，并随后分配到多个微孔（44）的每一个中。
-
14.发明申请A COMBINED RAPID ANTI-MICROBIAL SUSCEPTIBILITY ASSAY AND MICROORGANISM IDENTIFICATION SYSTEM 审中-公开组合快速抗微生物可检测性和微生物鉴定系统
公开(公告)号：WO0067037A2
公开(公告)日：2000-11-09
申请号：PCT/US0012751
申请日：2000-05-01
Applicant: DADE MICROSCAN INC
Inventor： WILLIAM GREGORY B , NOTHAFT DANIEL , ENSCOE GLENN F , BURTNER KATHLEEN N , KANGAS MONTE
CPC classification number: G01N35/028 , G01N35/0092 , G01N2035/0093 , G01N2035/0097
Abstract: In response to the need for highly-sensitive antibiotic susceptibility assays and identification assays that do not require extensive incubation times, the present invention provides automated assay methods and systems that permit the determination of antibiotic susceptibilities and/or microorganism identification in a timeframe that is substantially shorter than has previously been attainable using a hybrid system that combines turbimetric and fluorescence determinations using a single, clear-plastic assay platform. Related devices, kits, and components thereof are also disclosed.
Abstract translation: 为了响应不需要大量孵育时间的高灵敏度抗生素敏感性测定和鉴定测定的需要，本发明提供了自动化测定方法和系统，其允许在基本上在一定时间内测定抗生素敏感性和/或微生物鉴定 比使用混合系统以前可以获得的更短，该混合系统使用单一的透明塑料测定平台组合涡轮和荧光测定。 还公开了相关设备，套件及其组件。
-
-
Patent Agency Ranking
公开(公告)号：DE69314462T2
公开(公告)日：1998-05-20
申请号：DE69314462
申请日：1993-08-24
Applicant: DADE MICROSCAN INC
Inventor： COAKLEY JOSEPH , GODSEY JAMES , SHERMAN DAVID
Abstract: A sealable container for holding an analytical sample for processing is disclosed. The container includes a body with a dispensing port and an insert member with an outlet port slidably received in the body. The insert member and the body are movable relative to each other between a first position, in which the outlet port is substantially aligned with the dispensing port, and a second position, in which the outlet port is substantially out of alignment with the dispensing port. Sealing between the insert member and the body, which may take the form of O-rings, provide a substantially airtight, hermetic seal between a reaction chamber formed in the insert member and the body so that the reaction chamber can be sealed or isolated from the outside environment. The container is particularly adapted to contain the processes of nucleic acid amplification and to thereby reduce the problems of sample cross-contamination encountered in such processes. A method of processing an analytical sample using such a container is also disclosed.
-
公开(公告)号：DE69219989T2
公开(公告)日：1997-11-27
申请号：DE69219989
申请日：1992-04-29
Applicant: DADE MICROSCAN INC
Inventor： JOHNSTON JUDITH , FELLAND TRACY , BASCOMB SHOSHANA , GODSEY JAMES
Abstract: In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamese inducing antibiotic and a beta-lactam indicator antibiotic [which kills or inhibits the growth of bacteria] unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.
-
公开(公告)号：DE69221404D1
公开(公告)日：1997-09-11
申请号：DE69221404
申请日：1992-02-10
Applicant: DADE MICROSCAN INC
Inventor： SHERMAN DAVID , BUSH CHARLENE , BENINSIG LAURA , VANDENBRINK KURT
Abstract: Rare earth chelate-conjugated oligonucleotides useful in nucleic acid hybridization assays and for generating chelate-labelled probes of any desired sequence are disclosed. The particular class of chelates utilized exhibit an unusually high efficiency of rare earth element capture, correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy compared to other structurally related chelate compounds.
-
公开(公告)号：DE69213711D1
公开(公告)日：1996-10-17
申请号：DE69213711
申请日：1992-10-27
Applicant: DADE MICROSCAN INC
Inventor： GRINER CHRISTOPHER , MALONE BRIAN
Abstract: A holder for storing a specimen tray with a removable cover member includes a frame with oppositely facing first and second access openings The first access opening receives the specimen tray and cover member. The holder supports the specimen tray and cover member within the storage area between a pair of oppositely spaced tray support ledges. The second access opening receives an external member that moves vertically in the storage area to lift the specimen tray from the tray support ledges and that moves horizontally out of the storage area to move the lifted specimen tray from the storage area through the second access opening. The holder pivots the cover member away from the specimen tray to retain the cover member in a tilted orientation within the storage area free of the removed specimen tray until its return.
-
公开(公告)号：DE69121883D1
公开(公告)日：1996-10-10
申请号：DE69121883
申请日：1991-12-23
Applicant: DADE MICROSCAN INC
Inventor： BADAL ROBERT , KELLEY ROGER , SAND THEODORE , BASCOMB SHOSHANA
-
-
-
-
-
-
-
-
-
Search Results
59
records
(took 0.023 seconds)
