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11.发明申请公开(公告)号：US20210009710A1
公开(公告)日：2021-01-14
申请号：US17041220
申请日：2019-05-15
Applicant: GENOME AND COMPANY
Inventor： Kyoung Wan YOON , Youn Kyung HOUH , Bu-Nam JEON , Jinyoung SOHN , Yun Yeon KIM , Suro LEE , Joo-Yeon CHUNG , Areum JEONG
IPC: C07K16/28 , C12N15/113 , A61P35/00
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer, comprising an LRIT2 inhibitor as an active ingredient. The LRIT2 inhibitor according to the present invention can increase the activity of immune cells, and thus can be used as an immune enhancer. Also, the LRIT2 inhibitor according to the present invention can effectively prevent or treat cancer by enhancing the immunity of an individual.
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12.发明授权公开(公告)号：US11787870B2
公开(公告)日：2023-10-17
申请号：US17041220
申请日：2019-05-15
Applicant: GENOME AND COMPANY
Inventor： Kyoung Wan Yoon , Youn Kyung Houh , Bu-Nam Jeon , Jinyoung Sohn , Yun Yeon Kim , Suro Lee , Joo-Yeon Chung , Areum Jeong
IPC: C07K16/28 , A61P35/00 , C12N15/113
CPC classification number: C07K16/2896 , A61P35/00 , C12N15/1138 , C07K2317/55
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer, comprising an LRIT2 inhibitor as an active ingredient. The LRIT2 inhibitor according to the present invention can increase the activity of immune cells, and thus can be used as an immune enhancer. Also, the LRIT2 inhibitor according to the present invention can effectively prevent or treat cancer by enhancing the immunity of an individual.
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公开(公告)号：US20220387522A1
公开(公告)日：2022-12-08
申请号：US17769925
申请日：2020-10-16
Inventor： Hansoo PARK , Jinyoung SOHN , Yul Ha KIM
IPC: A61K35/745 , A61P37/04 , A23L33/135
Abstract: The present invention relates to a composition for enhancing or improving immunity comprising a Bifidobacterium bifidum. In addition, it can be used to prevent, treat, or improve immune diseases caused by immunodeficiency, immunosuppression, or immune system damage. It can be provided as a food composition or a pharmaceutical composition, and the food composition can be provided in various forms such as probiotic products, health functional supplements, animal feed, and the like.
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公开(公告)号：US11453857B2
公开(公告)日：2022-09-27
申请号：US17041740
申请日：2019-03-25
Applicant: Genome And Company , Lactomason Co., Ltd.
Inventor： Han Soo Park
IPC: A61K35/747 , C12N1/20 , A23K50/50 , A23K10/18 , A23L33/135 , A61P1/16 , A61P9/00 , A61P3/06 , A61P3/10 , A61P29/00
Abstract: The present disclosure relates to a novel strain of Lactobacillus fermentum LM1016 (KCCM12468P). The disclosed strain can be useful for treating or preventing cardiovascular diseases, obesity, fatty liver and/or diabetes. The present disclosure also relates to compositions comprising the strain. The compositions can be useful for medicines, health-functional foods, dairy products, fermented products, food additives, animal feeds, etc.
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公开(公告)号：US20210361723A1
公开(公告)日：2021-11-25
申请号：US15734900
申请日：2020-11-11
Applicant: LACTOMASON CO., LTD. , GENOME AND COMPANY
Inventor： Min Gyu JEON , Shin Young PARK , Yun Yeon KIM
IPC: A61K35/745 , A61P17/00 , A23L33/135
Abstract: This application claims the benefit under 35 USC 119(a) of Korean Patent Application No. 10-2017-0162218 filed on Nov. 30, 2016 in the Korean Intellectual Property Office, the entire disclosure of which is incorporated herein by reference for all purposes.
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Patent Agency Ranking
公开(公告)号：US20240182563A1
公开(公告)日：2024-06-06
申请号：US18285459
申请日：2022-04-05
Applicant: GENOME AND COMPANY
Inventor： Bu Nam JEON , Joo Yeon CHUNG , Soo Jung MOON , Hyunuk KIM , Mi Young CHA , Junho CHUNG , Junyeong JIN , Soohyun KIM , Jisu CHAE
CPC classification number: C07K16/2803 , A61K45/06 , A61K47/6849 , A61P35/00
Abstract: The present invention relates to an anti-CNTN4 antibody or an antigen-binding fragment thereof, a pharmaceutical composition containing the same, and a use thereof for activating T cells upregulating cell-mediated immune responses, for example, for treating cancer.
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公开(公告)号：US11571448B2
公开(公告)日：2023-02-07
申请号：US16645185
申请日：2018-09-06
Applicant: Genome And Company , Lactomason Co., Ltd.
Inventor： Han Soo Park
IPC: A61K35/747 , A61K35/00 , A23L33/135 , A23K10/18 , A23L33/00 , A61P3/04 , A61P3/10 , A61K9/00 , C12N1/20 , C12R1/225
Abstract: The present invention relates to a Lactobacillus rhamnosus LM1019 strain (accession number KCCM12308P), and a composition for preventing and treating obesity or diabetes mellitus, comprising the same. Specifically, the Lactobacillus rhamnosus LM1019 strain of the present invention reduces fat cells, neutral fats, subcutaneous fats, and cholesterol, thus having an effect of preventing and treating obesity, and also reduces the blood glucose concentration and the blood insulin concentration, thereby inhibiting insulin resistance and thus having an effect of preventing and treating diabetes mellitus.
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公开(公告)号：US20210299189A1
公开(公告)日：2021-09-30
申请号：US17270516
申请日：2019-05-24
Applicant: GENOME AND COMPANY
Inventor： Han-Soo PARK
Abstract: The present invention relates to Cutibacterium avidum GENSC01 strain (KCTC 13596BP). The present invention also relates to a composition comprising the strain or its culture, and use thereof. The present invention is effective in improvement, prevention or treatment of atopic dermatitis, acne or skin inflammation by fine dust.
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公开(公告)号：US20210138003A1
公开(公告)日：2021-05-13
申请号：US17096031
申请日：2020-11-12
Applicant: Genome And Company
Inventor： Hansoo Park , Shinyoung Park , Eun Ju Lee , Jae-Sung Yeon , Hye Hee Jeon , Wonduck Kim , Joo-Yeon Chung , Areum Jeong , Youn Kyung Houh , Jinyoung Sohn , Yun Yeon Kim , Sang Gyun Kim , Suro Lee
IPC: A61K35/745 , A61K31/282 , A61K31/519 , A61K33/243 , A61K31/7068 , A61K31/513 , A61K31/675 , A61K31/337 , A61K31/475 , A61K31/704 , A61K31/7048 , A61K39/395 , A61P35/00 , A61K35/744
Abstract: The present invention relates to a novel Bifidobacterium bifidum MG731 strain and a composition for preventing or treating cancers, comprising the same. Specifically, the Bifidobacterium bifidum MG731 strain of the present invention has effects of inhibiting the proliferation of cancer cells, decreasing the mobility of cancer cells, inhibiting the neoangiogenesis, and increasing the anticancer immune response as well as reducing the expression of inflammatory factors, thereby having effects of preventing or treating cancers or inflammatory diseases. In addition, when used in combination with an anticancer chemotherapeutic agent or an anticancer immunotherapeutic agent, the Bifidobacterium bifidum MG731 strain of the present invention exhibits a better anticancer effect. In addition, the present invention relates to a novel Lactococcus lactis GEN3033 strain and a composition for preventing or treating cancers, comprising the same. Specifically, the Lactococcus lactis GEN3033 strain of the present invention exhibits effects of directly inhibiting the proliferation of cancer cells and enhancing immunity, thereby having effects of preventing or treating cancers. In particular, the strain has an excellent anticancer effect by secreting metabolites having an anticancer effect while being established in the gut. In addition, when used in combination with an anticancer chemotherapeutic agent or an anticancer immunotherapeutic agent, the Lactococcus lactis GEN3033 strain of the present invention exhibits a better anticancer effect.
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公开(公告)号：US20250120903A1
公开(公告)日：2025-04-17
申请号：US18285157
申请日：2022-04-01
Applicant: GENOME AND COMPANY
Inventor： Riwon HONG , Hye Hee JEON , Suekyoung YOON , Jaesung YEON , Shinyoung PARK , Giduk BAE
Abstract: The present invention relates to a novel Sphingomonas paucimobilis strain. In addition, it relates to a use of Sphingomonas paucimobilis strain. Specifically, it relates to a method or composition for preventing or improving skin wrinkles, enhancing skin elasticity, reinforcing a skin barrier, or moisturizing the skin using the strain. The novel Sphingomonas paucimobilis strain according to the present invention can inhibit the expression of a collagen-degrading enzyme MMP-1, and promote the expression of collagen, filaggrin and claudin-1 that exhibit effects to improve skin wrinkles, enhance skin elasticity, strengthen skin barrier, and moisturize the skin. Therefore, the strain can be usefully used to prevent or improve skin wrinkles, enhance skin elasticity, strengthen the skin barrier, and/or moisturize the skin.
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