公开(公告)号：WO2012146980A3

公开(公告)日：2012-12-27

申请号：PCT/IB2012000922

申请日：2012-04-27

Applicant: REDDYS LAB LTD DR ,  KATKAM SRINIVAS ,  SAGYAM RAJESWAR REDDY ,  MORTHALA RAGHAVENDAR RAO ,  IRENI BABU ,  VINIGARI KRISHNA ,  RAMDOSS SURESH KUMAR ,  RANGINENI SRINIVASULU ,  TUMMALA ARJUNKUMAR ,  IQBAL JAVED ,  ORUGANTI SRINIVAS ,  KANDAGATLA BHASKAR

Inventor： KATKAM SRINIVAS ,  SAGYAM RAJESWAR REDDY ,  MORTHALA RAGHAVENDAR RAO ,  IRENI BABU ,  VINIGARI KRISHNA ,  RAMDOSS SURESH KUMAR ,  RANGINENI SRINIVASULU ,  TUMMALA ARJUNKUMAR ,  IQBAL JAVED ,  ORUGANTI SRINIVAS ,  KANDAGATLA BHASKAR

IPC: C07C211/00 ,  C07D333/20

CPC classification number: C07C205/45 ,  C07C201/10 ,  C07C201/12 ,  C07C213/00 ,  C07C213/02 ,  C07C213/10 ,  C07C215/28 ,  C07C205/04

Abstract: The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.

Abstract translation: 本申请提供了芬戈莫德及其药学上可接受的盐的制备方法，盐酸芬戈莫德的纯化方法和用于制备无定形芬戈莫德盐酸盐的方法。

公开(公告)号：WO2006034473A3

公开(公告)日：2006-12-14

申请号：PCT/US2005034243

申请日：2005-09-23

Applicant: REDDY US THERAPEUTICS INC ,  PAL MANOJIT ,  KALLEDA SRINIVAS ,  PADAKANTI SRINIVAS ,  KUMAR SWAMY NALIVELA ,  YELESWARAPU KOTESWAR RAO ,  ALEXANDER CHRISTOPHER W ,  KHANNA ISH KUMAR ,  IQBAL JAVED ,  PILLARISETTI SIVARAM ,  BARANGE DEEPAK

Inventor： PAL MANOJIT ,  KALLEDA SRINIVAS ,  PADAKANTI SRINIVAS ,  KUMAR SWAMY NALIVELA ,  YELESWARAPU KOTESWAR RAO ,  ALEXANDER CHRISTOPHER W ,  KHANNA ISH KUMAR ,  IQBAL JAVED ,  PILLARISETTI SIVARAM ,  BARANGE DEEPAK

IPC: A61K31/506 ,  C07D239/46 ,  C07D403/04

CPC classification number: C07D405/14 ,  C07D239/30 ,  C07D239/40 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/48 ,  C07D239/50 ,  C07D239/54 ,  C07D401/04 ,  C07D403/12 ,  C07D405/12

Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

Abstract translation: 本发明提供新的杂环化合物，特别是取代的嘧啶，用于制备和使用这些杂环化合物的方法和组合物，以及用于治疗各种疾病和疾病状态的方法，包括动脉粥样硬化，关节炎，再狭窄，糖尿病性肾病或血脂异常或疾病 由Perlecan低表达介导的状态。

公开(公告)号：WO2006073610A8

公开(公告)日：2006-09-08

申请号：PCT/US2005042736

申请日：2005-11-23

Applicant: REDDY US THERAPEUTICS INC ,  PAL MANOJIT ,  RAO YELESWARAPU KOTESWAR ,  KHANNA ISH KUMAR ,  SWAMY NALIVELA KUMARA ,  SUBRAMANIAN VENKATARAMAN ,  BATCHU VENKATESWARA RAO ,  IQBAL JAVED ,  PILLARISETTI SIVARAM

Inventor： PAL MANOJIT ,  RAO YELESWARAPU KOTESWAR ,  KHANNA ISH KUMAR ,  SWAMY NALIVELA KUMARA ,  SUBRAMANIAN VENKATARAMAN ,  BATCHU VENKATESWARA RAO ,  IQBAL JAVED ,  PILLARISETTI SIVARAM

IPC: A61K31/519 ,  C07D487/02

CPC classification number: C07D471/04 ,  C07D487/04

Abstract: The present invention provides, among other things, new bicyclo heterocyclic compounds, compositions comprising these heterocyclic compounds, methods of making the heterocyclic compounds, and methods of using these heterocyclic compounds for treating a variety of conditions and disease states associated with, for example, cellular proliferation, inflammation, glycosidase expression, or the low expression of Perlecan.

Abstract translation: 本发明尤其提供了新的双环杂环化合物，包含这些杂环化合物的组合物，制备杂环化合物的方法，以及使用这些杂环化合物治疗与例如细胞相关的多种病症和疾病状态的方法 增殖，炎症，糖苷酶表达或Perlecan的低表达。

公开(公告)号：WO2005035528A3

公开(公告)日：2005-06-02

申请号：PCT/IB2004003360

申请日：2004-10-14

Applicant: REDDYS LAB LTD DR ,  NATESAN SELVAKUMAR ,  DAS JAGATTARAN ,  TAKHI MOHAMED ,  TREHAN SANJAY ,  IQBAL JAVED ,  MAGADI SITARAM KUMAR ,  KANDEPU SREENIVAS

Inventor： NATESAN SELVAKUMAR ,  DAS JAGATTARAN ,  TAKHI MOHAMED ,  TREHAN SANJAY ,  IQBAL JAVED ,  MAGADI SITARAM KUMAR ,  KANDEPU SREENIVAS

IPC: A61K31/395 ,  A61K31/495 ,  A61K31/55 ,  A61P31/00 ,  C07D401/14 ,  C07D403/10

CPC classification number: C07D401/14 ,  C07D403/10

Abstract: The present invention relates to novel triazole compounds of formula (I), their prodrugs, their pharmaceutically acceptable salts and their stereoisomers thereof. The present invention also relates to a process for the preparation of the novel compound of the formula (I).

Abstract translation: 本发明涉及式（I）的新型三唑化合物，其前药，其药学上可接受的盐及其立体异构体。 本发明还涉及制备式（I）的新型化合物的方法。

公开(公告)号：WO2004101531A1

公开(公告)日：2004-11-25

申请号：PCT/IB2004/001303

申请日：2004-04-29

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DAS, Jagattaran ,  NATESAN, Selvakumar ,  TREHAN, Sanjay ,  IQBAL, Javed ,  MAGADI, Sitaram, Kumar

Inventor： DAS, Jagattaran ,  NATESAN, Selvakumar ,  TREHAN, Sanjay ,  IQBAL, Javed ,  MAGADI, Sitaram, Kumar

IPC: C07D249/06

CPC classification number: C07D249/08 ,  C07D403/10

Abstract: The present invention relates to novel triazole compounds of formula (I), thie pharmaceutically acceptable salts and their pharmaceutical compositions, where all symbols have meaning as defined in the description, for use in the treatment of bacterial infections.

Abstract translation: 本发明涉及式（I）的新型三唑化合物，其药学上可接受的盐及其药物组合物，其中所有符号具有如说明书中定义的含义，用于治疗细菌感染。

公开(公告)号：WO2004069145A2

公开(公告)日：2004-08-19

申请号：PCT/IB2004000299

申请日：2004-02-06

Applicant: REDDYS LAB LTD DR ,  VEDULA MANOHAR SHARMA ,  KATTUBOINA VENKATA ADISESHU ,  IQBAL JAVED ,  RAMANUJAM RAJAGOPALAN ,  RAJAGOPAL SRIRAM ,  MAMIDI NAGA VENKATA SRINIVASA ,  JOSYULA RAMANATHAM ,  GUTTA MADHUSUDHAN

Inventor： VEDULA MANOHAR SHARMA ,  KATTUBOINA VENKATA ADISESHU ,  IQBAL JAVED ,  RAMANUJAM RAJAGOPALAN ,  RAJAGOPAL SRIRAM ,  MAMIDI NAGA VENKATA SRINIVASA ,  JOSYULA RAMANATHAM ,  GUTTA MADHUSUDHAN

IPC: A61K20060101 ,  C07D215/00 ,  C07D215/44 ,  C07D215/54 ,  C07D239/72 ,  C07D239/94 ,  A61K

CPC classification number: C07D239/94 ,  C07D215/44 ,  C07D215/54

Abstract: The present invention relates to novel anticancer agents, their pharmaceutically acceptable salts, their geometrical isomers and their pharmaceutically acceptable compositions containing them. the present invention more particularly relates to novel quinazoline compounds, their pharmaceutically acceptable salts and their pharmaceutically acceptable compositions containing them. the novel quinazoline compounds have the general formula (I), where all symbols are as defined in the specification.

Abstract translation: 本发明涉及新型抗癌剂，其药学上可接受的盐，它们的几何异构体及其含有它们的药学上可接受的组合物。 本发明更具体地涉及新的喹唑啉化合物，其药学上可接受的盐及其含有它们的药学上可接受的组合物。 新的喹唑啉化合物具有通式（I），其中所有符号如说明书中所定义。

公开(公告)号：WO2003048116A2

公开(公告)日：2003-06-12

申请号：PCT/IB2002/005064

申请日：2002-12-02

Applicant: DR. REDDY'S LABORATORIES LTD. ,  BHUNIYA, Debnath ,  DAS, Saibal, Kumar ,  MADHAVAN, Gurram, Ranga ,  IQBAL, Javed ,  CHAKRABARTI, Ranjan ,  VIKRAMADITHYAN, Reeba, Kannimel

Inventor： BHUNIYA, Debnath ,  DAS, Saibal, Kumar ,  MADHAVAN, Gurram, Ranga ,  IQBAL, Javed ,  CHAKRABARTI, Ranjan ,  VIKRAMADITHYAN, Reeba, Kannimel

IPC: C07C309/00

CPC classification number: A61K31/353 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/541 ,  C07C309/66 ,  C07C309/73 ,  C07C311/53

Abstract: The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to compounds of the general formula (I) which are predominantly PPAR alpha agonists, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them The present invention also relates to processes for the preparation of novel compounds of formula (I), novel intermediates, processes for their preparation, use of the novel intermediates in the preparation of the above said compounds and their use as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds.

Abstract translation: 本发明涉及式（I）的新型抗糖尿病，降血脂，抗胆固醇和低胆固醇血症化合物，其衍生物，其类似物，其互变异构形式，其立体异构体，其多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和药学上可接受的组合物，其含有 他们。 更具体地说，本发明涉及通式（I）的化合物，其主要是PPARα激动剂，它们的衍生物，它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶型物，其药学上可接受的盐，其药学上可接受的溶剂合物和药学上可接受的溶剂合物 含有它们的可接受的组合物本发明还涉及式（I）的新型化合物的制备方法，新型中间体，其制备方法，新型中间体在制备上述化合物中的用途及其作为抗糖尿病， 降血脂，抗肥胖和低胆固醇血症化合物。

公开(公告)号：WO2003033456A1

公开(公告)日：2003-04-24

申请号：PCT/IB2002/004274

申请日：2002-10-15

Applicant: DR. REDDY'S LABORATORIES LTD. ,  BHUNIYA, Debnath ,  DAS, Saibal, Kumar ,  MADHAVAN, Gurram, Ranga ,  IQBAL, Javed ,  CHAKRABARTI, Ranjan

Inventor： BHUNIYA, Debnath ,  DAS, Saibal, Kumar ,  MADHAVAN, Gurram, Ranga ,  IQBAL, Javed ,  CHAKRABARTI, Ranjan

IPC: C07C229/34

CPC classification number: C07C229/42 ,  C07C229/34 ,  C07D265/36 ,  C07D279/16

Abstract: The present invention relates to novel propionic acid derivatives. More particularly, the present invention relates to beta-phenyl alpha-oxysubstituted propionic acids of the general formula (I). The present invention also relates to processes for the preparation of compounds of the formula (I) and their use in the preparation of compounds of formula (II).

Abstract translation: 本发明涉及新型丙酸衍生物。 更具体地说，本发明涉及通式（I）的β-苯基α-氧代取代丙酸。 本发明还涉及制备式（I）化合物及其在制备式（II）化合物中的用途的方法。

公开(公告)号：WO2009032326A1

公开(公告)日：2009-03-12

申请号：PCT/US2008/010462

申请日：2008-09-08

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DR. REDDY'S LABORATORIES INC. ,  TAKHI, Mohamed ,  SELVAKUMAR, Natesan ,  KANDEPU, Sreenivas ,  RAJULU, Gavara Govinda ,  IQBAL, Javed

Inventor： TAKHI, Mohamed ,  SELVAKUMAR, Natesan ,  KANDEPU, Sreenivas ,  RAJULU, Gavara Govinda ,  IQBAL, Javed

IPC: C07D205/04 ,  C07D211/60 ,  C07D211/62 ,  C07D401/06 ,  C07D405/04 ,  C07D409/04 ,  A61K31/33 ,  A61P31/04

CPC classification number: C07D205/04 ,  C07D207/16 ,  C07D211/60 ,  C07D211/62 ,  C07D401/06 ,  C07D405/04 ,  C07D409/04

Abstract: In accordance with one embodiment, the present invention provides a compound of general formula (I), stereoisomers thereof and/or its pharmaceutically acceptable salts thereof, which have antibacterial activity; with methods of treating infectious diseases in warm blooded animals employing these new compounds.

Abstract translation: 根据一个实施方案，本发明提供具有抗菌活性的通式（I）的化合物，其立体异构体和/或其药学上可接受的盐; 使用这些新化合物治疗温血动物感染性疾病的方法。

公开(公告)号：WO2007002461A1

公开(公告)日：2007-01-04

申请号：PCT/US2006/024572

申请日：2006-06-23

Applicant: DR. REDDY'S LABORATORIES LTD. ,  DR. REDDY'S LABORATORIES, INC. ,  POTLURI, Vijay Kumar ,  DAS, Saibal Kumar ,  SASMAL, Pradip Kumar ,  IQBAL, Javed ,  MISRA, Parimal ,  CHAKRABARTI, Ranjan ,  TALWAR, Rashmi

Inventor： POTLURI, Vijay Kumar ,  DAS, Saibal Kumar ,  SASMAL, Pradip Kumar ,  IQBAL, Javed ,  MISRA, Parimal ,  CHAKRABARTI, Ranjan ,  TALWAR, Rashmi

IPC: A61K31/426 ,  A61K31/427 ,  C07D277/38 ,  C07D417/02

CPC classification number: C07D277/42 ,  C07D417/12

Abstract: The present application provides novel thiazole derivatives that are useful as activators of Adenosine 5'-Monophosphate-Activated Protein Kinase and pharmaceutical compositions containing such compounds.

Abstract translation: 本申请提供了可用作腺苷5'-单磷酸激活蛋白激酶的激活剂的新型噻唑衍生物和含有这些化合物的药物组合物。