公开(公告)号：AU2005286592A1

公开(公告)日：2006-03-30

申请号：AU2005286592

申请日：2005-09-23

Applicant: REDDY US THERAPEUTICS INC ,  PAL MANOJIT ,  KALLEDA SRINIVAS ,  PADAKANTI SRINIVAS ,  SWAMY NALIVELA KUMAR ,  KOTESWAR YELESWARAPU ,  CHRISTOPHER ALEXANDER ,  ISH KHANNA ,  IQBAL JAVED ,  PILLARISETTI SIVARAM ,  BARANGE DEEPAK

Inventor： BARANGE DEEPAK ,  ALEXANDER CHRISTOPHER W ,  KALLEDA SRINIVAS ,  PAL MANOJIT ,  SWAMY NALIVELA KUMAR ,  YELESWARAPU KOTESWAR RAO ,  PADAKANTI SRINIVAS ,  PILLARISETTI SIVARAM ,  IQBAL JAVED ,  KHANNA ISH KUMAR

IPC: A61K31/506 ,  C07D239/46 ,  C07D403/04

公开(公告)号：EP1796673A2

公开(公告)日：2007-06-20

申请号：EP05799686.0

申请日：2005-09-23

Applicant: Reddy US Therapeutics, Inc. ,  Kalleda, Srinivas ,  Padakanti, Srinivas ,  Swamy, Nalivela, Kumara ,  Rao, Yeleswarapu Koteswar ,  Alexander, Christopher W. ,  Khanna, Ish Kumar ,  Iqbal, Javed ,  Pillarisetti, Sivaram ,  Pal, Manojit ,  Barange, Deepak

Inventor： PAL, Manojit ,  KALLEDA, Srinivas ,  PADAKANTI, Srivinas ,  KUMAR SWAMY, Nalivela, Plor 191, J.P.N. ,  YELESWARAPU, Koteswar, Rao,Flat 202,Krishna Arcade ,  ALEXANDER, Christopher, W. ,  KHANNA, Ish, Kumar ,  IQBAL, Javed, Flat 101, Sri Krishna Residency ,  PILLARISETTI, Sivaram ,  BARANGE, Deepak, H.No.235, c/o A. Srinivas

IPC: A61K31/506 ,  C07D403/04 ,  C07D239/46

CPC classification number: C07D405/14 ,  C07D239/30 ,  C07D239/40 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/48 ,  C07D239/50 ,  C07D239/54 ,  C07D401/04 ,  C07D403/12 ,  C07D405/12

Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

公开(公告)号：WO2006034473A3

公开(公告)日：2006-12-14

申请号：PCT/US2005034243

申请日：2005-09-23

Applicant: REDDY US THERAPEUTICS INC ,  PAL MANOJIT ,  KALLEDA SRINIVAS ,  PADAKANTI SRINIVAS ,  KUMAR SWAMY NALIVELA ,  YELESWARAPU KOTESWAR RAO ,  ALEXANDER CHRISTOPHER W ,  KHANNA ISH KUMAR ,  IQBAL JAVED ,  PILLARISETTI SIVARAM ,  BARANGE DEEPAK

Inventor： PAL MANOJIT ,  KALLEDA SRINIVAS ,  PADAKANTI SRINIVAS ,  KUMAR SWAMY NALIVELA ,  YELESWARAPU KOTESWAR RAO ,  ALEXANDER CHRISTOPHER W ,  KHANNA ISH KUMAR ,  IQBAL JAVED ,  PILLARISETTI SIVARAM ,  BARANGE DEEPAK

IPC: A61K31/506 ,  C07D239/46 ,  C07D403/04

CPC classification number: C07D405/14 ,  C07D239/30 ,  C07D239/40 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/48 ,  C07D239/50 ,  C07D239/54 ,  C07D401/04 ,  C07D403/12 ,  C07D405/12

Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

Abstract translation: 本发明提供新的杂环化合物，特别是取代的嘧啶，用于制备和使用这些杂环化合物的方法和组合物，以及用于治疗各种疾病和疾病状态的方法，包括动脉粥样硬化，关节炎，再狭窄，糖尿病性肾病或血脂异常或疾病 由Perlecan低表达介导的状态。

公开(公告)号：WO2006034474A2

公开(公告)日：2006-03-30

申请号：PCT/US2005/034244

申请日：2005-09-23

Applicant: REDDY US THERAPEUTICS, INC. ,  KALLEDA, Srinivas ,  PADAKANTI, Srinivas ,  KUMARSAMY, Nalivela ,  ALEXANDER, Christopher W. ,  KHANNA, Ish ,  IQBAL, Javed ,  PILLARISETTI, Ram ,  MAITRA, Santanu ,  ROBERTS, Gayla, R. ,  SAGI, Lavanya

Inventor： KALLEDA, Srinivas ,  PADAKANTI, Srinivas ,  KUMARSAMY, Nalivela ,  ALEXANDER, Christopher W. ,  KHANNA, Ish ,  IQBAL, Javed ,  PILLARISETTI, Ram ,  MAITRA, Santanu ,  ROBERTS, Gayla, R. ,  SAGI, Lavanya ,  YELESWARAPU, Koteswar Rao

IPC: A61K31/541 ,  A61K31/5377 ,  A61K31/496 ,  A61K31/4545 ,  A61K31/4439 ,  A61K31/44 ,  C07D417/02 ,  C07D403/02 ,  C07D413/02 ,  C07D401/02

CPC classification number: C07D405/14 ,  C07D239/30 ,  C07D239/40 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/48 ,  C07D239/50 ,  C07D239/54 ,  C07D401/04 ,  C07D403/12 ,  C07D405/12

Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyridines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

Abstract translation: 本发明提供新的杂环化合物，特别是取代的吡啶，制备和使用这些杂环化合物的方法和组合物，以及用于治疗各种疾病和疾病状态的方法，包括动脉粥样硬化，关节炎，再狭窄，糖尿病性肾病或血脂异常或疾病 由Perlecan低表达介导的状态。

公开(公告)号：WO2006034473A2

公开(公告)日：2006-03-30

申请号：PCT/US2005/034243

申请日：2005-09-23

Applicant: REDDY US THERAPEUTICS, INC. ,  KALLEDA, Srinivas ,  PADAKANTI, Srinivas ,  KUMAR SWAMY, Nalivela ,  YELESWARAPU, Koteswar, Rao ,  ALEXANDER, Christopher, W. ,  KHANNA, Ish, Kumar ,  IQBAL, Javed ,  PILLARISETTI, Sivaram ,  PAL, Manojit ,  BARANGE, Deepak

Inventor： KALLEDA, Srinivas ,  PADAKANTI, Srinivas ,  KUMAR SWAMY, Nalivela ,  YELESWARAPU, Koteswar, Rao ,  ALEXANDER, Christopher, W. ,  KHANNA, Ish, Kumar ,  IQBAL, Javed ,  PILLARISETTI, Sivaram ,  PAL, Manojit ,  BARANGE, Deepak

IPC: A61K31/541 ,  A61K31/5377 ,  A61K31/496 ,  A61K31/4545 ,  A61K31/4439 ,  A61K31/44 ,  C07D417/02 ,  C07D403/02 ,  C07D413/02 ,  C07D401/02

CPC classification number: C07D405/14 ,  C07D239/30 ,  C07D239/40 ,  C07D239/42 ,  C07D239/46 ,  C07D239/47 ,  C07D239/48 ,  C07D239/50 ,  C07D239/54 ,  C07D401/04 ,  C07D403/12 ,  C07D405/12

Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.

Abstract translation: 本发明提供了新的杂环化合物，特别是取代的嘧啶，制备和使用这些杂环化合物的方法和组合物，以及治疗多种疾病和疾病状态的方法，包括动脉粥样硬化，关节炎，再狭窄， 糖尿病性肾病或血脂异常，或由基底膜蛋白低表达介导的疾病状态。