Abstract:
The present invention relates to a preparation method of Lactobacillus parabuchneri LA15 strain cells accumulating rare earth elements, the strain cells prepared by the method, a composition containing the strain cells, and a biological leaching method using the Lactobacillus parabuchneri LA15 strain cells.
Abstract:
PURPOSE: A polypeptide for deoxynojirimycin(DNJ) synthesis is provided to produce a large amount of DNJs using a transformant and to develop an agent for reducing blood glucose. CONSTITUTION: An amino acid sequence for DNJ biosynthesis is denoted by sequence number 10. A nucleic acid molecule relating to DNJ biosynthesis is isolated from Bacillus subtilis sp. A recombinant vector contains the nucleic acid molecules. A host cell is transformed using the recombinant vector. The host cell is yeast, Bacillus subtilis or Escherichia coli. A method for producing polypeptides for DNJ biosynthesis comprises: a step of transforming the host cells with the recombinant vector; and a step of culturing the host cells to collect polypeptides.
Abstract:
A proteus mirabilis derived amino acid deaminase gene is provided to massively produce various functional organic acid by bioconversion with amino acid substrate. A gene having the activity of amino acid deaminase which is isolated from proteus mirabilis CC3-1 has a nucleotide of the sequence number 1. An enzyme protein is produced from the gene. A recombinant vector comprises the gene. The tranformant is transformed with the recombinant vector. The transformant is selected among E.coli, Streptomyces sp. bacteria, Saccharomyces sp. yeast, Pichia sp. yeast and Rhodotorula sp. yeast. The functional organic acid is produced by performing bioconversion of the enzyme with amino acid which is a substrate. The substrate is selected among a phenyl alanine, isleucine, leucine, tyrosine, valine and lysine.
Abstract:
본발명에따른바실러스서브틸리스모리균주를이용한고상배양물의제조방법을통해 1-데옥시노지리마이신을함유하는고상배양물을고효율저비용으로대량생산할수 있으며, 본발명의고상배양물은비만, 당뇨, 지질관련대사성질환또는바이러스성질병의예방또는치료용약제학적조성물의소재로서유용하게활용될수 있다.
Abstract:
The present invention relates to a preparation method of Pichia kurdriavzevii LA30 strain cells accumulating rare earth elements, the strain cells prepared by the method, a composition containing the strain cells, and a biological leaching method using the Pichia kurdriavzevii LA30 strain cells
Abstract:
본 발명은 아코니텀(Aconitum)속 식물인 초오(草烏) 또는 부자(附子)에 바실러스 서브틸리스 MORI( Bacillus subtilis MORI) 균주를 접종하여 함께 발효시킴으로써 독성물질의 농도가 감소된 초오 또는 부자 발효물을 제조하는 방법 및 상기 발효물을 유효성분으로 포함하는 조성물에 관한 것으로, 본 발명의 방법에 따르면, 초오와 부자 내에 있는 유용물질의 농도변화 없이, 독성물질인 아코니틴의 농도를 감소시킨 발효 초오추출물을 대량으로 생산할 수 있으며, 이에 따라 한의학에서 초오를 처방하게 될 경우 발효초오를 처방함으로써 기존 초오를 처방할 때의 위험부담을 줄일 수 있다. 초오(草烏, Aconiti ciliare tuber), 부자(附子, Aconitum carmichaeli DEBX), 아코니틴(aconitine), 바실러스 서브틸리스 MORI(Bacillus subtilis MORI), 한약재수치(韓藥材修治, processing of medicinal plant for reduction of toxicity)
Abstract:
PURPOSE: A Proteus vulgaris P2-1(KACC 91462P) which produces amino acid deaminase and a method for preparing organic acid using the same are provided to be used in antibacterial agent, disinfectant, sterilizing agent, and antibiotics. CONSTITUTION: A Proteus vulgaris P2-1 strain produces amino acid deaminase. A method for preparing organic acid comprises a step of culturing Proteus vulgaris P2-1(KACC 91462P) in a medium containing amino acid, and a step of collecting organic acid from the culture. The amino acid is phenylalanine and organic acid is phenyl lactic acid.
Abstract:
PURPOSE: A method for manufacturing aconitum Aconitum Jaluense or Aconitum Carmichaelii Debeaux fermentation is provided to produce a large amount of fermented Aconitum Jaluense extract. CONSTITUTION: A method for manufacturing Aconitum Jaluense or Aconitum Carmichaelii Debeaux fermentation with a reduced toxic material concentration comprises: a step of extracting Aconitum Jaluense or Aconitum Carmichaelii Debeaux with a solvent; and a step of culturing Bacillus substilis MORI(deposit number: KCCM10450) strain and culturing. The solvent is water, spirit, chloroform, hexane, or mixture thereof. The toxic material is aconitine.
Abstract:
본 발명은 다양한 장내 병원성 세균을 효과적으로 억제할 수 있는 프로바이오틱(probiotic) 유산균 및 이를 포함하는 프로바이오틱 조성물에 관한 것으로, 본 발명의 락토바실러스 크리스파투스( Lactobacillus crispatus ) G19 균주 및 비피도박테리움 보움( Bifidobacterium boum ) R5 균주는 다양한 병원성 세균에 대해 우수한 항균 활성을 나타냄은 물론 내산성 및 내담즙성 등이 우수하고, 락토바실러스 크리스파투스 G19의 경우 우수한 장상피세포부착능을, 그리고 비피도박테리움 보움 R5의 경우 내산소성 및 건조 열에 대한 우수한 안정성을 나타내므로, 사료, 식품, 의약품 및 화장품 등의 제조에 유용하게 활용될 수 있다.