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公开(公告)号：KR1020110089043A
公开(公告)日：2011-08-04
申请号：KR1020100011390
申请日：2010-02-08
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A skin condition measuring method is provided to measure a skin condition using a parameter data value which is defined by a skin condition level and a correlation index. CONSTITUTION: A parameter is defined by a skin condition level and a correlation index(S110). Parameter data are collected wherein the parameter data is set in a skin by a measuring unit of a measuring device(S120). Collected parameters are analyzed, a skin condition level is determined according to a parameter data value, and the determined skin condition level is provided(S130). A parameter includes at least one element from a group which includes a skin moisture amount, skin brightness, a skin melanin index, and a skin erythema index.
Abstract translation: 目的：提供皮肤状态测量方法，以使用由皮肤状况水平和相关指数定义的参数数据值来测量皮肤状况。 构成：参数由皮肤状态等级和相关指数定义（S110）。 收集参数数据，其中通过测量装置的测量单元将参数数据设置在皮肤中（S120）。 分析收集的参数，根据参数数据值确定皮肤状态水平，并且提供所确定的皮肤状况水平（S130）。 参数包括至少一个来自组中的元素，其包括皮肤水分量，皮肤亮度，皮肤黑色素指数和皮肤红斑指数。
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公开(公告)号：KR1020110058291A
公开(公告)日：2011-06-01
申请号：KR1020090115031
申请日：2009-11-26
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K2800/591 , A61K2800/70 , A61K2800/82 , A61Q5/00 , A61Q5/002
Abstract: PURPOSE: A hair composition containing red ginseng extract and Mori Radicis Cortex or Scutellariae radix extract is provided to strengthen hair roots and to be used in various hair products. CONSTITUTION: A hair composition for strengthening hair roots contains 0.01-10.0 weight% of red ginseng extract, Mori Radicis Cortex extract, or Scutellariae radix extract as an active ingredient. The hair composition is manufactured in the form of hair tonic, hair lotion, hair essence, hair serum scalp treatment, hair treatment, hair conditioner, or hair shampoo. The red ginseng extract is prepared by ultrasonic wave extraction. The Mori Radicis Cortex extract is prepared by extracting at low temperature. The Scutellariae radix extract is prepared by extracting with 1,3-butylene glycol and a water mixture and macerating.
Abstract translation: 目的：提供含有红参提取物，芒果红皮质或黄芩提取物的头发组合物，以增强发根，并用于各种头发产品中。 构成：用于加强发根的头发组合物含有0.01-10.0重量％的红参提取物，番茄提取物或黄芩提取物作为活性成分。 头发组合物以滋养剂，洗发剂，头发精华，头发血清头皮治疗，头发护理，护发素或洗发剂的形式制造。 红参提取物通过超声波提取制备。 Mori Radicis Cortex提取物通过在低温下提取而制备。 黄芩提取物通过用1,3-丁二醇和水混合物萃取并浸渍而制备。
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公开(公告)号：KR1020100037907A
公开(公告)日：2010-04-12
申请号：KR1020080097246
申请日：2008-10-02
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A hair cosmetic composition containing water in which green tea leaves are brewed is provided to suppress itch of scalp and restore damaged hair. CONSTITUTION: A hair cosmetic composition contains 0.01-10.0 weight% of water in which green tea is brewed. The green tea water is extracted by infusing at low temperature. The green tea leaves are streamed and dried. The composition contains methylchloroisotiazolinone and methylisotiazolinone in methyl ρ-hydroxybenoate.
Abstract translation: 目的：提供一种含有绿茶叶的水的头发化妆品组合物，以抑制头皮瘙痒并恢复损伤的头发。 构成：头发化妆品组合物含有0.01-10.0重量％的酿造绿茶的水。 绿茶水通过低温灌注而提取。 绿茶叶被流出并干燥。 该组合物在对羟基苯甲酸甲酯中含有甲基氯代噻唑啉酮和甲基异噻唑啉酮。
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公开(公告)号：KR1020100014100A
公开(公告)日：2010-02-10
申请号：KR1020090034997
申请日：2009-04-22
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A cosmetic composition containing fermentation extract of natural product is provided to ensure anti-oxidation through suppression of DPPH(1,1-diphenyl-2-picryl hydrazyl) and wrinkle improvement through procollagen promotion and collagenase expression suppression. CONSTITUTION: A cosmetic composition contains fermentation extract of salted red bean, mung bean, or black bean as an active ingredient. The cosmetic composition contains fermentation extract in which deep sea water is added. The composition is used for anti-oxidation and anti-aging. A method for producing the fermentation extract of salted natural product comprises: a step of adding salt or deep sea water to red bean, mung bean or black bean, and fermenting to obtain fermentation of natural product; and a step of extracting the fermentation of salted natural product with water or organic solvent.
Abstract translation: 目的：提供含有天然产物发酵提取物的化妆品组合物，以通过抑制DPPH（1,1-二苯基-2-苦基酰肼）和促进胶原酶表达的抑制来改善皱纹。 构成：化妆品组合物含有咸红豆，绿豆或黑豆的发酵提取物作为活性成分。 化妆品组合物含有添加深海水的发酵提取物。 该组合物用于抗氧化和抗老化。 盐化天然产物发酵提取物的制备方法包括：向红豆，绿豆或黑豆加盐或深海水，并发酵得到天然产物发酵的步骤; 以及用水或有机溶剂提取盐化天然产物的发酵步骤。
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15.发明授权Ｒｈｏ ＧＤＩ-α를 포함하는 멜라닌 생성 조절용 조성물및 Ｒｈｏ ＧＤＩ-α를 이용하여 멜라닌 생성 조절제를스크리닝하는 방법 失效用于控制含有Rho GDI-的黑素生成的组合物，以及使用Rho GDI-α筛选黑素生成调节剂的方法
公开(公告)号：KR100912355B1
公开(公告)日：2009-08-14
申请号：KR1020070121200
申请日：2007-11-27
Applicant: (주)아모레퍼시픽
Abstract: Rho GDI-α 단백질 또는 그 단백질을 코딩하는 유전자를 이용하여 멜라닌 생성을 억제하는 조성물과 Rho GDI-α 단백질을 이용하여 멜라닌 생성을 억제하는 물질을 스크리닝하는 방법이 개시된다. 또한, Rho GDI-α의 발현을 저해하는 siRNA 유전자를 이용하여 멜라닌 생성을 촉진하는 조성물과 siRNA 유전자를 이용하여 멜라닌 생성을 촉진하는 물질을 스크리닝하는 방법이 개시된다. 본 발명을 이용하면 멜라닌 생성을 효과적으로 촉진 또는 억제할 수 있으며 멜라닌 생성을 촉진 또는 억제하는 물질을 효과적으로 스크리닝할 수 있다.
Rho GDI-α, MITF, 타이로시나제, 멜라닌 생성 촉진, 멜라닌 생성 억제, 멜라닌-
Patent Agency Ranking
公开(公告)号：KR100775333B1
公开(公告)日：2007-11-08
申请号：KR1020060114331
申请日：2006-11-20
Applicant: (주)아모레퍼시픽
IPC: G01N33/48
Abstract: A screening method of pigmentation regulatory agents by using zebrafish(Danio rerio) is provided to screen a large quantity of materials capable of increasing or inhibiting melanin formation as pigmentation regulatory agents easily and rapidly by determining various biological parameters from zebrafish. A screening method of pigmentation regulatory agents by using zebrafish comprises the steps of: administering a candidate pigmentation regulatory agent into an embryo of zebrafish; and detecting the reactions of zebrafish including expression amount of melanin formation, and in vivo activity, expression amount or transition amount of proteins associated with melanin formation, wherein the screening method optionally comprises a detecting step of toxicity of the candidate material by measuring morphological change or heartbeat number.
Abstract translation: 提供通过使用斑马鱼（Danio rerio）的色素调节剂的筛选方法，通过确定斑马鱼的各种生物参数，可以容易且快速地筛选大量能够增加或抑制黑色素形成的物质，作为色素调节剂。 通过使用斑马鱼的色素调节剂的筛选方法包括以下步骤：将候选色素调节剂施用于斑马鱼的胚胎; 检测斑马鱼的反应，包括黑色素形成的表达量以及与黑色素形成相关的蛋白质的体内活性，表达量或转化量，其中所述筛选方法任选地包括通过测量形态学变化或候选物质的毒性检测步骤， 心跳数
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公开(公告)号：KR100774437B1
公开(公告)日：2007-11-08
申请号：KR1020060113662
申请日：2006-11-17
Applicant: (주)아모레퍼시픽
IPC: A61K31/343 , A61K8/49 , A61Q19/02
CPC classification number: A61K8/4973 , A61K31/343 , A61Q19/02
Abstract: A skin external composition for skin-whitening containing manassantin B is provided to inhibit mobility of melanin by inhibiting binding of melanophilin as a carrier of melanosome in a melanocyte with myosin 5a, thereby forming melanosome aggregation and whitening the skin. A skin external composition for skin-whitening contains 0.001-10% of manassantin B which is extracted from Saururus chinensis Baill by extracting Saururus chinensis Baill with water or organic solvent selected from ethanol, methanol, butanol, ether, ethylacetate, chloroform and methylene chloride, filtering the extract, concentrating the filtered solution under reduced pressure, extracting the concentrate with methylene chloride and concentrating the extract under reduced pressure, and is formulated as solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation or spray.
Abstract translation: 提供含有马桑丁汀B的皮肤外用组合物，用于通过抑制作为黑素细胞的黑素体的载体的黑色素细胞与肌球蛋白5a的结合来抑制黑色素的迁移，从而形成黑素体聚集并使皮肤变白。 用于皮肤美白的皮肤外用组合物含有0.001-10％的苦参碱B，其通过用水或选自乙醇，甲醇，丁醇，乙醚，乙酸乙酯，氯仿和二氯甲烷的有机溶剂萃取中华白菜， 过滤浓缩滤液，减压浓缩萃取液，减压浓缩，配制成溶液，悬浮液，乳液，糊剂，凝胶，乳液，乳液，粉末，皂，表面活性剂， 含有清洁，油，粉底，乳液粉底，蜡基或喷雾剂。
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公开(公告)号：KR100643514B1
公开(公告)日：2006-11-23
申请号：KR1020050041060
申请日：2005-05-17
Applicant: (주)아모레퍼시픽
IPC: C07C233/64 , A61K8/368
Abstract: Provided are a hydroxybenzoic acid amide compound which suppresses the generation of melanin, its preparation method, and a whitening cosmetic composition containing the compound. The hydroxybenzoic acid amide compound is represented by the formula 1, wherein R1 and R2 are H or OH. The method comprises the steps of dissolving hydroxybenzoic acid in a solvent, adding a catalyst and a base drop by drop, and reacting it with acetic anhydride to prepare an acetylated compound represented by the formula II; dissolving the acetylated compound of the formula II in a solvent and adding a base, ethyl chloroformate and adamantamine to prepare an amide compound represented by the formula III; and reacting the amine compound of the formula III with a base to hydrolyze it (See the reaction scheme 1), wherein R3 and R4 is H or an acetoxy group.
Abstract translation: 本发明提供抑制黑色素生成的羟基苯甲酸酰胺化合物及其制备方法和含有该化合物的美白化妆品组合物。 羟基苯甲酸酰胺化合物由式1表示，其中R 1和R 2是H或OH。 该方法包括以下步骤：将羟基苯甲酸溶解在溶剂中，逐滴加入催化剂和碱，并使其与乙酸酐反应以制备式II表示的乙酰化化合物; 将式II的乙酰化的化合物溶解在溶剂中并加入碱，氯甲酸乙酯和金刚烷胺以制备式III表示的酰胺化合物; 和使式III的胺化合物与碱反应以水解（参见反应方案1），其中R 3和R 4是H或乙酰氧基。
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公开(公告)号：KR101781169B1
公开(公告)日：2017-09-22
申请号：KR1020150116268
申请日：2015-08-18
Applicant: (주)아모레퍼시픽
Abstract: 본발명은녹차다당체의제조방법에관한것으로, 보다상세하게는 a) 용매를이용하여녹차분말에서엽록소및 저분자량의폴리페놀을제거하는단계; b) 상기 a)단계의녹차잔사로부터수용성활성성분을열수추출하는단계; 및 c) 상기 b)단계의열수추출물로부터한외여과및 에탄올침전반응으로녹차다당체를분리하는단계를포함하는것을특징으로하는녹차다당체의제조방법에관한것이다. 본발명에따라제조한녹차다당체를함유하는화장료조성물은우수한피부미백, 보습및 주름개선효과를나타낸다.
Abstract translation: 本发明包括作为制造绿茶多糖的方法，更具体地，以除去叶绿素和从绿茶粉使用a）溶剂的低分子量的多元酚; b）从步骤a）的绿茶残余物中水热提取水溶性活性成分; 和c）通过超滤和乙醇沉淀反应从步骤b）的热水提取物中分离绿茶多糖。 含有根据本发明制备的绿茶多糖的化妆品组合物表现出优异的皮肤增白，保湿和减皱效果。
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公开(公告)号：KR1020170091567A
公开(公告)日：2017-08-09
申请号：KR1020170097086
申请日：2017-07-31
Applicant: (주)아모레퍼시픽
CPC classification number: A61K36/75 , A61K8/97 , A61Q19/005 , A61Q19/007
Abstract: 본발명은무라야패니쿨라타추출물을유효성분으로포함하는피부가려움증완화및 억제, 피부보습, 피부염증완화및 억제, 피부면역성강화, 피부과민반응개선또는아토피피부개선및 치료용조성물을개시한다.
Abstract translation: 本发明公开了一种村的同伴库拉其他皮肤瘙痒缓解包括提取物作为活性成分和抑制，皮肤保湿剂，皮肤炎症和抑制，皮肤免疫增强，皮肤致敏改善或特应性皮肤改善和治疗组合物。
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