Abstract:
PURPOSE: A pharmaceutical composition containing melitin ingredients is provided to treat liver diseases. CONSTITUTION: A pharmaceutical composition for treating liver diseases contains 0.001-0.05 wt% of melittin as an active ingredient. Mellitin is isolated from honey bee-derived bee venom. The composition additionally contains pharmaceutically acceptable carrier. Mellitin reduces inflammation-inducing cytokine expression in a liver tissue. The inflammation-inducing cytokine is TNF-alpha, IL-1beta, IL-6, or VCAM. [Reference numerals] (AA) Tumor necrosis factor(TNF-α); (BB) NC control group; (CC) TAA experimental group of liver cirrhosis; (DD) TAA + Mel experimental group of liver cirrhosis + melittin administration
Abstract:
PURPOSE: A composition for suppressing melanogenesis is provided to ensure excellent melanogenesis suppression. CONSTITUTION: A composition for suppressing melanogenesis contains S-(-)-10,11-dihydroxyfarnesic acid methyl ester as an active ingredient. The active ingredient is isolated from insect-derived fungi. S-dihydroxyfarnesic acid methyl ester is prepared by extracting the fungi with ethyl acetate and isolating and purifying. A pharmaceutical composition contains the composition. A cosmetic composition contains the composition. The composition is manufactured in the form of a lotion, liquid, emulsion, suspension, tablet, or capsule.
Abstract:
본 발명은 실크단백질을 이용한 치주 골조직유도 재생용 차폐막 및 그 제조방법에 관한 것이다. 본 발명의 치주 골조직유도 재생용 차폐막의 제조방법은 실크 단백질로부터 세리신을 제거하여 실크 피브로인을 얻는 단계; 상기 실크 피브로인을 염을 포함한 에탄올수용액으로 용해시켜 실크 피브로인 염 에탄올수용액을 제조하는 단계; 상기 실크 피브로인 염 에탄올수용액으로부터 염과 에탄올을 제거하여 실크 피브로인 수용액을 제조하는 단계;및 상기 실크 피브로인 수용액을 평평한 용기에 붓고 건조하는 단계;를 포함한다. 본 발명에 의해, 상처 부위의 밀착성이 우수할 뿐만 아니라 골조직 재생성도 우수하고 생체내 생분해성을 갖는 치주 골조직유도 재생용 차폐막 및 그 제조방법이 제공된다.
Abstract:
PURPOSE: An injection method of cordyceps spawns to silkworm pupae, and a cultivation method of cordyceps using the same are provided to improve the productivity of the cordyceps. CONSTITUTION: An injection method of cordyceps spawns to silkworm pupae comprises the following steps: storing cordyceps liquid spawns in a container; inserting silkworm pupae into the cordyceps liquid spawns, and soaking for 0.5-3 minutes; and sealing the container, and impregnating the cordyceps liquid spawns into the silkworm pupae with the pressure of 0.5 ~ 2kg per square centimeter.
Abstract translation:目的:采用冬虫夏草注射法产蚕蛹,并提供冬虫夏草的培养方法,以提高冬虫夏草的生产率。 构成:冬虫夏草诱导蚕蛹的注射方法包括以下步骤:将虫草液体产卵储存在容器中; 将蚕蛹插入冬虫夏草液中,浸泡0.5-3分钟; 并密封容器,并以0.5〜2kg / cm 2的压力将冬虫夏草液体产卵浸入蚕蛹中。
Abstract:
PURPOSE: An extract of Protaetia brevitarsis which has almost the same liver protecting effect as silymarin as a conventional liver disease treating agent is provided which can be effectively used as an effective ingredient for a liver disease treating agent or health supplementary agent. CONSTITUTION: Distilled water is added to larvae powder of Protaetia brevitarsis and extracted and the extract is passed through a dialysis membrane to produce a Protaetia brevitarsis extract having a molecular weight of 1,000 or less. The extract is formulated to be administered in a dose of 1 to 2,500mg/kg/day, preferably 10 to 500mg/kg/day and can recover the liver effectively when hepatotoxicity is induced by drugs such as carbon dioxide.
Abstract translation:目的:提供一种与常规肝脏疾病治疗剂具有几乎与水飞蓟素相同的肝脏保护作用的紫薇球茎提取物,其可以有效地用作肝病治疗剂或保健补充剂的有效成分。 组成:将蒸馏水加入到短尾叶蝉幼虫粉末中并提取,并将提取物通过透析膜,以产生分子量为1,000或更低的Protaetia brevitarsis提取物。 提取物配制为以1至2,500mg / kg /天,优选10至500mg / kg /天的剂量施用,并且当由诸如二氧化碳的药物诱导肝毒性时可以有效地回收肝脏。
Abstract:
PURPOSE: Provided is an antibiotic sanitary fabric produced of silk yarn and cellulose separated from waste milk packs, which can be used for various application, as a covering and has antibiotic activity effects. CONSTITUTION: The fabric is made of silk yarn which is prepared by purifying waste silk and cellulose which are separated from waste milk packs. The fabric is produced by carrying out a method comprising steps of (i) preparing silk yarn by purifying waste silk; (ii) preparing cellulose by treating waste milk packs; and (iii) mixing the silk yarn prepared from the step (i) and the cellulose prepared from the step (ii) to form an antibiotic sanitary fabric. The mixing ratio of cellulose to silk yarn is about 1:0.3.
Abstract:
본 발명은 실크피브로인을 단백질 분해효소로 분해한 펩타이드의 제조에 관한것이다. 실크(견사)를 효소분해하여 견단백질인 피브로인을 얻고 이를 염화칼슘과 에탄올에 반응시켜 투석하여 얻은 용액에 단백질 분해효소인 플라보자임(flavourzyme) 및 액티나제(actinase)로 분해하여 동결건조한 후 분말상의 피브로인 펩타이드를 제조하였다. 이들 펩타이드는 분자량이 12,000 - 13,000이고 중합도가 163으로서 pH 1 - 13에서 70% 용해도를 나타내고 있으므로 체내 흡수율이 높아 항산화작용과 알콜대사분해능력이 탁월하여 기능성 식품 또는 의약품으로 사용과 각 성분에 대한 순수 활성물질의 개발에 기여할 수 있다.