公开(公告)号：KR100286390B1

公开(公告)日：2001-04-16

申请号：KR1019980000581

申请日：1998-01-12

Applicant: 대한민국(농촌진흥청장)

Inventor： 송정춘 ,  이상양 ,  박남규 ,  허한순 ,  성낙술

IPC: A61K36/804 ,  A61K36/258 ,  A61K36/076

Abstract: PURPOSE: A process of preparing Kyungokgo(Korean native name) as a kind of a restorative herb medicine for promoting blood circulation by heating several medicinal plants is provided. Whereby, the product is in a jelly state such as a bar of sweetened and jellied bean paste without a gel state available in the market. The process is simple and advantageous to put to practical use. CONSTITUTION: Kyungokgo containing Rehmanniae radix, ginseng powder, Poria cocos powder, honey and the like in a gel state and prepared by the prescription of the Dongeuibogam published in Korea as a book on oriental medicine is heated with 2 times of water at 95 to 100deg.C for 10 min and filtered with a filter paper at a pressure of 50Kgf/cm¬3. And 50% by weight of the Kyungokgo extract is mixed with a forming material comprising 2.0% by weight of agar, 28% by weight of sugar and 20% by weight of dregs of adzuki beans and concentrated, followed by cooling.

公开(公告)号：KR1020010016877A

公开(公告)日：2001-03-05

申请号：KR1019990032077

申请日：1999-08-05

Applicant: 대한민국(농촌진흥청장)

Inventor： 송정춘 ,  박남규 ,  허한순 ,  이상양 ,  백남인

IPC: C07D209/04 ,  A61K31/4045

Abstract: PURPOSE: A method for isolating and purifying natural antioxidant N-feruloylserotonin from safflower seeds is provided, thereby the high purity natural antioxidant N-feruloylserotonin is simply and rapidly obtained from safflower seeds. CONSTITUTION: The method for isolating and purifying natural antioxidant N-feruloylserotonin comprises the steps of: grinding safflower seeds and extracting the grinded safflower seeds with methanol; sequentially dividing the extract into ethylacetate, normal butanol and water fractions; dissolving the ethylacetate fraction into organic solvent and passing it through column chromatography to collect several fractions; passing the fractions through TLC and collecting fractions that have the same development distant; and measuring DPPH radical activity of fractions to isolate antioxidant, in which methanol is 70 to 90%, and the extraction is performed at room temperature for 1 day.

Abstract translation: 目的：提供从红花种子中分离纯化天然抗氧化剂N-亚铁血清素的方法，从而从红花种子中快速获得高纯度天然抗氧化剂N-阿魏酸血清素。 方法：分离纯化天然抗氧化剂N-亚铁血清素的方法，包括以下步骤：研磨红花种子，用甲醇提取研磨的红花种子; 将提取物依次分为乙酸乙酯，正丁醇和水组分; 将乙酸乙酯级分溶解在有机溶剂中并通过柱层析，收集几份; 将级分通过TLC并收集具有相同发育距离的级分; 测定各部分的DPPH自由基活性，分离出甲醇为70〜90％的抗氧化剂，并在室温下进行1天的提取。