公开(公告)号：KR1020070013639A

公开(公告)日：2007-01-31

申请号：KR1020050068094

申请日：2005-07-26

Applicant: 대한민국 (식품의약품안전처장)

Inventor： 최기환 ,  윤재석 ,  김은엽 ,  오세관 ,  류종훈 ,  나한광 ,  이윤희 ,  김주일 ,  김동섭 ,  이석호

IPC: A61K36/66 ,  A61K36/539 ,  A61P29/00

CPC classification number: A61K36/539 ,  A61K36/66 ,  A61K2236/331

Abstract: Anodynes with reduced drug addiction are provided to improve use safety of anodynes while they maintains pain-alleviating effects by adding natural products capable of reducing drug addiction into anodynes. The anodynes with reduced drug addiction comprises morphine or nalbuphine as an anodyne, Scutellariae radix extract, betaine, and a pharmaceutically acceptable carrier, wherein the Scutellariae radix extract is prepared by heating Scutellariae radix in water and drying it, wherein the weight ratio of morphine or nalbuphine, Scutellariae radix extract and betaine is 1: 66: 44.

Abstract translation: 提供降低药物成瘾性的痴呆症，以改善痴呆症的使用安全性，同时通过添加能够将药物成瘾减少为无效的天然产物来维持疼痛缓解作用。 具有降低药物成瘾性的痴呆症包括吗啡或纳布啡作为an ne，黄芩提取物，甜菜碱和药学上可接受的载体，其中黄芩提取物通过在水中加热黄芩并干燥而制备，其中吗啡或 纳布啡，黄芩提取物和甜菜碱为1:66:44。