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公开(公告)号：KR1020070013639A
公开(公告)日：2007-01-31
申请号：KR1020050068094
申请日：2005-07-26
Applicant: 대한민국 (식품의약품안전처장)
IPC: A61K36/66 , A61K36/539 , A61P29/00
CPC classification number: A61K36/539 , A61K36/66 , A61K2236/331
Abstract: Anodynes with reduced drug addiction are provided to improve use safety of anodynes while they maintains pain-alleviating effects by adding natural products capable of reducing drug addiction into anodynes. The anodynes with reduced drug addiction comprises morphine or nalbuphine as an anodyne, Scutellariae radix extract, betaine, and a pharmaceutically acceptable carrier, wherein the Scutellariae radix extract is prepared by heating Scutellariae radix in water and drying it, wherein the weight ratio of morphine or nalbuphine, Scutellariae radix extract and betaine is 1: 66: 44.
Abstract translation: 提供降低药物成瘾性的痴呆症，以改善痴呆症的使用安全性，同时通过添加能够将药物成瘾减少为无效的天然产物来维持疼痛缓解作用。 具有降低药物成瘾性的痴呆症包括吗啡或纳布啡作为an ne，黄芩提取物，甜菜碱和药学上可接受的载体，其中黄芩提取物通过在水中加热黄芩并干燥而制备，其中吗啡或 纳布啡，黄芩提取物和甜菜碱为1:66:44。
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公开(公告)号：KR101360109B1
公开(公告)日：2014-02-12
申请号：KR1020110127108
申请日：2011-11-30
Applicant: 대한민국 (식품의약품안전처장) , 경희대학교 산학협력단 , 서울대학교산학협력단
IPC: A61K31/7048 , A61K31/70 , A61P25/28
CPC classification number: A61K31/7048 , A23L2/52 , A23L33/10 , A23L33/135 , A23V2002/00 , A61K36/185 , A61K36/42 , A61K36/47 , A61K36/48 , A61K36/725
Abstract: 본 발명의 스피노신 또는 스피노신 함유 생약 추출물을 포함하는 약학 조성물은 인지기능 장애 질환을 예방 및 치료하는 조성물로, 기억 및 학습 능력을 효과적으로 향상시켜 치매 및 건망증과 같은 인지기능 장애 질환을 효과적으로 치료 및 예방할 수 있다.
Abstract translation: 本发明的药物组合物，其含有刺糖苷或含刺糖多糖的草药提取物，是用于预防和治疗认知功能障碍的组合物，可有效提高记忆力和学习能力，有效治疗和预防认知功能障碍如痴呆 和健忘症。
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公开(公告)号：KR100715939B1
公开(公告)日：2007-05-09
申请号：KR1020050068095
申请日：2005-07-26
Applicant: 대한민국 (식품의약품안전처장)
IPC: A61K36/539 , A61K36/898 , A61P29/00
Abstract: 본 발명은 황금추출물, 베타인 또는 이들의 혼합물을 유효성분으로 하고, 약제학적으로 허용되는 담체를 포함하는 마약중독 치료제에 관한 것이다. 본 발명의 마약중독 치료제는 마약성 진통제의 투여에 의하여 형성되는 약물 의존성을 효과적으로 억제할 수 있으므로, 안전하고 효과적인 마약성 진통제의 부작용 해소에 널리 활용될 수 있을 것이다.
마약중독, 황금추출물, 베타인-
4.发明公开
公开(公告)号：KR1020020050362A
公开(公告)日：2002-06-27
申请号：KR1020000079495
申请日：2000-12-21
Applicant: 대한민국 (식품의약품안전처장) , 대한민국(관리부서 : 산림청 국립산림과학원장)
IPC: A61K36/896
Abstract: PURPOSE: A pharmaceutical composition containing an Allium victorialis var. platyphyllum extract having a therapeutic and preventing activity against arteriosclerosis as an effective component is provided which can be effectively used as a pharmaceutical component and an effective component of functional food for prevention and treatment of arteriosclerosis and hypercholesterolemia. CONSTITUTION: A dried Allium victorialis var. platyphyllum is ground to 20 to 100 mesh, mixed 2 to 5 times with ethanol and extracted at 15 to 50deg.C for 24 to 96 hr. The extract remarkably reduces the amount of cholesterol and lipid peroxide in blood and has an inhibition activity on cholesteryl ester transfer protein enzyme for transferring HDL cholesterol to arteriosclerosis-inducing low density lipoprotein cholesterol.
Abstract translation: 目的：一种含有Allium victorialis var。 提供具有抗动脉硬化作用的治疗和预防活性的青蒿提取物作为有效成分，其可以有效地用作药物组分和用于预防和治疗动脉硬化和高胆固醇血症的功能食品的有效成分。 构成：干燥的Allium victorialis var。 将青蒿素研磨至20至100目，用乙醇混合2至5次，并在15至50℃下提取24至96小时。 提取物显着降低血液中胆固醇和脂质过氧化物的含量，对胆固醇酯转移蛋白酶具有抑制活性，用于将HDL胆固醇转移至动脉硬化诱导低密度脂蛋白胆固醇。
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Patent Agency Ranking
公开(公告)号：KR1020080008929A
公开(公告)日：2008-01-24
申请号：KR1020060114284
申请日：2006-11-20
Applicant: 대한민국 (식품의약품안전처장)
IPC: A61K31/352 , A61P25/28 , A23L1/29 , A23L1/30
Abstract: A health functional food comprising Oroxylin A is provided to improve spatial-perceptual ability of an animal group of which memory is decreased by scopolamine and carotid ligation, thereby being usefully used for treating and preventing cognitive impairment. A health functional food for preventing and improving Alzheimer's disease or cerebro vascular dementia comprises Oroxylin A and a sitologically acceptable food supplemental additive, wherein the Oroxylin A is isolated from an extract of Scutellaria baicalensis GEORGI. The food is in the form of powder, granule, tablet, capsule or drink.
Abstract translation: 提供了包含奥昔木蛋白A的健康功能食品，以提高通过东莨菪碱和颈动脉结扎使记忆减少的动物组的空间感知能力，从而有效地用于治疗和预防认知障碍。 一种用于预防和改善阿尔茨海默病或脑血管性痴呆的健康功能食品包括奥昔木蛋白A和可食用的食品补充添加剂，其中，从黄芩黄芩提取物中分离出OroxylA A. 食物为粉末，颗粒，片剂，胶囊或饮料。
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公开(公告)号：KR100779419B1
公开(公告)日：2007-11-30
申请号：KR1020050068094
申请日：2005-07-26
Applicant: 대한민국 (식품의약품안전처장)
IPC: A61K36/66 , A61K36/539 , A61P29/00
Abstract: 몰핀 또는 날부핀인 진통제와 황금추출물, 베타인 또는 이들의 혼합물인 중독성 경감물질의 혼합물을 유효성분으로 하고, 약제학적으로 허용되는 담체를 포함하는 중독성이 경감된 진통제에 관한 것이다. 본 발명의 중독성이 경감된 진통제는 마약성 진통제의 투여에 의하여 형성되는 약물 의존성을 경감시킬 수 있으므로, 안전하고 효과적인 통증 해소에 널리 활용될 수 있을 것이다.
몰핀, 날부핀, 마약성 진통제, 황금추출물, 베타인-
公开(公告)号：KR1020130060835A
公开(公告)日：2013-06-10
申请号：KR1020110127108
申请日：2011-11-30
Applicant: 대한민국 (식품의약품안전처장) , 경희대학교 산학협력단 , 서울대학교산학협력단
IPC: A61K31/7048 , A61K31/70 , A61P25/28
CPC classification number: A61K31/7048 , A23L2/52 , A23L33/10 , A23L33/135 , A23V2002/00 , A61K36/185 , A61K36/42 , A61K36/47 , A61K36/48 , A61K36/725
Abstract: PURPOSE: A pharmaceutical composition containing spinosin or a spinosin-containing crude drug extract is provided to effectively improve memory and learning ability and to effectively prevent and treat cognitive disorders such as dementia and amnesia. CONSTITUTION: A composition for preventing or treating cognitive disorder contains spinosin. The composition also contains one or more extracts selected from a group consisting of Zizyphus jujuba Mill var. inermis, Zizyphus jujuba Mill var. hoonensis, Zizyphus jujuba Mill var. spinosa, Passiflora edulis flavicarpa, Cayaponia tayuya, Desmodium tortuosum, Wilbrandia ebracteata, Strophioblachia fimbricalyx, Clutia abyssinica, and Saccharopolyspora spinosa. The cognitive disorders are dementia or amnesia. A food composition for preventing or treating cognitive disorders contains spinosin. [Reference numerals] (AA) Delay time(seconds); (BB) In the middle of learning; (CC) In the middle of the present experiment; (DD) Control group 3; (EE) Control group 2; (FF) Medicine injected group 1; (GG) Medicine injected group 2; (HH) Medicine injected group 3; (II) Medicine injected group 4; (JJ) Control group 1
Abstract translation: 目的：提供含有刺糖苷或含刺糖苷的生药提取物的药物组合物，有效提高记忆力和学习能力，有效预防和治疗认知障碍，如痴呆和遗忘症。 构成：用于预防或治疗认知障碍的组合物含有刺糖苷。 该组合物还含有一种或多种提取物，选自Zizyphus jujuba Mill var。 Z hus枣 枣树，枣树 菠萝，西番莲，洋葱，Cataaponia tayuya，枸杞，Wilbrandia ebracteata，Strophioblachia fimbricalyx，黑蛤和Saccharopolyspora spinosa。 认知障碍是痴呆或遗忘症。 用于预防或治疗认知障碍的食物组合物含有刺糖苷。 （附图标记）（AA）延迟时间（秒）; （BB）在学习的中间; （CC）在本实验中期; （DD）对照组3; （EE）对照组2; （FF）药物注射组1; （GG）药物注射组2; （HH）药物注射组3; （二）药物注射组4; （JJ）对照组1
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公开(公告)号：KR1020070013640A
公开(公告)日：2007-01-31
申请号：KR1020050068095
申请日：2005-07-26
Applicant: 대한민국 (식품의약품안전처장)
IPC: A61K36/539 , A61K36/898 , A61P29/00
CPC classification number: A61K36/539 , A61K2236/331 , Y10S514/812
Abstract: A therapeutic agent for narcotics addiction is provided to inhibit drug addiction of the narcotic anodynes, so that side effects of the narcotic anodynes are suppressed. The therapeutic agent for narcotics addiction comprises the Scutellariae radix extract and betaine as effective ingredients, and a pharmaceutically acceptable carrier, wherein the Scutellariae radix extract is prepared by extracting Scutellariae radix with hot water, and drying and pulverizing it; and the mixing ratio of Scutellariae radix extract and betaine is 4:6 to 7:3.
Abstract translation: 提供麻醉药物成瘾的治疗剂以抑制麻醉药物成瘾，从而抑制麻醉药物的副作用。 毒瘾治疗剂包括黄芩提取物和甜菜碱作为有效成分，以及药学上可接受的载体，其中黄芩提取物通过用热水提取黄芩制备，并干燥并粉碎; 黄芩提取物和甜菜碱的混合比为4：6〜7：3。
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公开(公告)号：KR100387279B1
公开(公告)日：2003-06-12
申请号：KR1020000079495
申请日：2000-12-21
Applicant: 대한민국 (식품의약품안전처장) , 대한민국(관리부서 : 산림청 국립산림과학원장)
IPC: A61K36/896
Abstract: PURPOSE: A pharmaceutical composition containing an Allium victorialis var. platyphyllum extract having a therapeutic and preventing activity against arteriosclerosis as an effective component is provided which can be effectively used as a pharmaceutical component and an effective component of functional food for prevention and treatment of arteriosclerosis and hypercholesterolemia. CONSTITUTION: A dried Allium victorialis var. platyphyllum is ground to 20 to 100 mesh, mixed 2 to 5 times with ethanol and extracted at 15 to 50deg.C for 24 to 96 hr. The extract remarkably reduces the amount of cholesterol and lipid peroxide in blood and has an inhibition activity on cholesteryl ester transfer protein enzyme for transferring HDL cholesterol to arteriosclerosis-inducing low density lipoprotein cholesterol.
Abstract translation: 目的：一种含有葱属植物变种的药物组合物。 提供具有针对动脉硬化的治疗和预防活性的扁桃酚提取物作为有效成分，其可以有效地用作用于预防和治疗动脉硬化和高胆固醇血症的功能性食品的药物成分和有效成分。 组成：干韭菜var。 将Platyphyllum粉碎至20至100目，用乙醇混合2至5次，并在15至50℃提取24至96小时。 该提取物显着降低血液中胆固醇和脂质过氧化物的量，并且对胆固醇酯转移蛋白酶具有抑制活性，用于将HDL胆固醇转化为诱导动脉硬化的低密度脂蛋白胆固醇。
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