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公开(公告)号：KR1020150016036A
公开(公告)日：2015-02-11
申请号：KR1020130092249
申请日：2013-08-02
Applicant: 삼성전자주식회사
CPC classification number: C12Q1/6806 , C12Q1/6834 , C12N1/066 , C12Q1/37 , C12Q1/6844 , C12Q2521/537 , C12Q2523/301
Abstract: Provided is a method for amplifying the nucleic acid of a cell by dissolving the cell specifically bonded to a solid support. By means of the same, without a separate step of isolating a cell specifically bonded to a solid support or the nucleic acid of the same, the nucleic acid can be amplified from the cell specifically bonded to the solid support.
Abstract translation: 提供了通过将特异性结合到固体支持物上的细胞溶解来扩增细胞核酸的方法。 通过相同的方式，没有分离特异性结合到固体支持物或其核酸的细胞的单独步骤，可以从特异性结合到固体支持物的细胞扩增核酸。
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公开(公告)号：KR1020150011699A
公开(公告)日：2015-02-02
申请号：KR1020130086968
申请日：2013-07-23
Applicant: 삼성전자주식회사
CPC classification number: C12Q1/6858 , C12Q1/6827 , C12Q2600/156 , C12Q2537/163
Abstract: Provided are: a composition or a kit for detecting nucleic acids containing genetic variation which comprises a first amplification inhibiting nucleic acid and a second amplification inhibiting nucleic acid; and a method for detecting nucleic acids containing genetic variation using the same. By using the composition or the method, nucleic acids comprising genetic variation can be detected with excellent sensitivity and accuracy.
Abstract translation: 提供：用于检测含有遗传变异的核酸的组合物或试剂盒，其包含第一扩增抑制性核酸和第二扩增抑制性核酸; 以及使用该遗传变异检测含有遗传变异的核酸的方法。 通过使用该组合物或方法，可以以极好的灵敏度和准确度检测出包含遗传变异的核酸。
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公开(公告)号：KR1020140073215A
公开(公告)日：2014-06-16
申请号：KR1020120141199
申请日：2012-12-06
Applicant: 삼성전자주식회사
IPC: G01N33/53 , G01N33/543 , C12Q1/24
CPC classification number: G01N1/34 , G01N33/54326 , G01N33/574
Abstract: By using a composition, a kit, or a method of separating cells using the same including a complex of at least one type of a linker capable of specifically binding to an antibody or antigen binding fragment and a complex of a solid support unit, cells can be effectively separated from a sample. Moreover, a disease can be diagnosed by detecting the separated cells.
Abstract translation: 通过使用包含能够特异性结合抗体或抗原结合片段的至少一种类型的接头的复合物和固体支持单元的复合物的组合物，试剂盒或分离细胞的方法，细胞可以 与样品有效分离。 此外，可以通过检测分离的细胞来诊断疾病。
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公开(公告)号：KR101911436B1
公开(公告)日：2018-10-25
申请号：KR1020120053778
申请日：2012-05-21
Applicant: 삼성전자주식회사
Abstract: 샘플내에있는소정크기이상의세포나입자들을용이하게포획할수 있는동시에포획된세포나입자들에의한유로의폐색(clogging)을방지하고포획된세포나입자들에작용하는스트레스를감소시킬수 있는필터가개시된다. 개시된필터는제 1 표면을갖는제 1 기판및 상기제 1 기판의제 1 표면과접합되는제 2 표면을갖는제 2 기판을포함하며, 상기제 1 기판은샘플이흐르도록제 1 표면에형성된유로및 상기유로를가로질러돌출된배리어를포함하고, 상기제 2 기판은상기돌출부와대응하는제 2 표면상의영역에형성된미세홈을포함할수 있으며, 상기돌출부의표면과상기미세홈 사이에간극이존재할수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020150017611A
公开(公告)日：2015-02-17
申请号：KR1020130093790
申请日：2013-08-07
Applicant: 삼성전자주식회사
CPC classification number: C12N15/1013 , C12N15/1006 , C12Q1/6806 , C12Q1/6834
Abstract: The present invention relates to a method for separating a nucleic acid from cells, a composition for preventing the adsorption of a nucleic acid on the surface of a solid support, and a kit for separating a nucleic acid from cells. The method for separating a nucleic acid from cells comprises the steps of: incubating a sample and a solid support including cells, and attaching the cells on the solid support; making the solid support attached to the cells be suspended in a composition including alkali metal salts of 100-300 mM and having pH 6-8; and obtaining a nucleic acid from the solution obtained by lysis.
Abstract translation: 本发明涉及从细胞中分离核酸的方法，用于防止核酸在固体支持物表面的吸附的组合物和用于从细胞中分离核酸的试剂盒。 从细胞中分离核酸的方法包括以下步骤：将样品和包含细胞的固体支持物孵育，并将细胞附着在固体支持物上; 使附着在细胞上的固体支持物悬浮在包含100-300mM碱金属盐和pH 6-8的组合物中; 从裂解获得的溶液中得到核酸。
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公开(公告)号：KR1020140055145A
公开(公告)日：2014-05-09
申请号：KR1020120121539
申请日：2012-10-30
Applicant: 삼성전자주식회사
IPC: G01N33/53 , G01N33/533
CPC classification number: G01N33/6893 , G01N33/574 , G01N33/582
Abstract: The present invention relates to a method of sequential and multiple immunostaining for detection of various antigens in the same specimens. The immunostaining method can be used for qualitative or quantitative analysis of proteins expressed, gene analysis, and morphological analysis even in specimens where only a small amount is available. Fluorescent pigments according to an embodiment of the present invention are selected from a group consisting of FITC, DAPI, Cy5, Cy3, Texas Red and Rhodamine.
Abstract translation: 本发明涉及用于检测相同样品中各种抗原的顺序和多重免疫染色的方法。 免疫染色方法可用于定性或定量分析表达的蛋白质，基因分析和形态学分析，即使在只有少量可用的样品中。 根据本发明的实施方案的荧光颜料选自FITC，DAPI，Cy5，Cy3，德克萨斯红和罗丹明。
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公开(公告)号：KR1020140028529A
公开(公告)日：2014-03-10
申请号：KR1020120095001
申请日：2012-08-29
Applicant: 삼성전자주식회사
IPC: C07K19/00 , G01N33/68 , G01N33/574
Abstract: The present invention relates to linker polypeptides, a composition or a kit comprising the same, and a method for analyzing a target material using the same. When the linker polypeptides are used, signal distortion which can be caused by micro-particles when analyzing a target material is prevented, thereby being useful for increasing accuracy and reliability of diagnosis. [Reference numerals] (AA) Fc-binding domain; (BB) TEV cutting domain; (CC) C-terminal modification
Abstract translation: 本发明涉及接头多肽，组合物或包含其的试剂盒，以及使用该多肽的靶材料的分析方法。 当使用接头多肽时，可以防止在分析目标材料时由微粒引起的信号失真，从而有助于提高诊断的准确性和可靠性。 （AA）Fc结合结构域; （BB）TEV切割领域; （CC）C末端修饰
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19.发明公开표적물질을 결합시키기 위한 금 나노클러스터가 표면에 형성된 금속 나노와이어 및 표적물질을 상기 금속 나노와이어에 결합시키는 방법 审中-实审在金属纳米粒子上形成的金属纳米结构用于结合目标材料的表面和用目标材料结合金属纳米线的方法
公开(公告)号：KR1020130010344A
公开(公告)日：2013-01-28
申请号：KR1020110071090
申请日：2011-07-18
Applicant: 삼성전자주식회사
CPC classification number: C23C16/06 , B22F1/0025 , B22F1/025 , B82Y30/00 , C22C5/02 , C23C16/0281 , G01N33/553 , Y10T428/12771
Abstract: PURPOSE: A metal nanowire in which gold nanocluster is formed on the surface and a method of binding for the metal nanowire with target material are provided to efficiently bond with target material at high affinity. CONSTITUTION: A metal nanowire in which gold nanocluster is formed on the surface is existed in the composition form. The gold nanocluster has average size of 1-10 nano meters. The gold nanocluster is existed in the density range of 1X10^6 - 1X10^16clusters/cm^2. A manufacturing method of the metal nanowire comprises the following steps: forming a gold thin film layer on a metal board; forming gold - metal island by primary sintering the gold containing metal substrate in a chamber for chemical vapor deposition; and injecting mixing gas into the chamber while secondary sintering the silicon substrate to grow metal nanowire in which gold nanocluster is formed on the surface. [Reference numerals] (AA) Trapping rate(%); (BB) Culturing time(minutes)
Abstract translation: 目的：提供一种金属纳米线，其中在表面上形成金纳米颗粒，并提供与目标材料结合金属纳米线的方法，以高亲和力高效地与目标材料结合。 构成：在表面形成金纳米簇的金属纳米线以组成形式存在。 金纳米簇的平均尺寸为1-10纳米。 金纳米簇存在于1×10 ^ 6〜1×10 ^ 16簇/ cm 2的密度范围内。 金属纳米线的制造方法包括以下步骤：在金属板上形成金薄膜层; 通过在用于化学气相沉积的室中初始烧结含金属金属基底来形成金 - 金属岛; 以及将混合气体注入所述室中，同时二次烧结所述硅衬底以生长在其上形成金纳米簇的金属纳米线。 （附图标记）（AA）捕获率（％）; （BB）培养时间（分钟）
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