감초 가공 추출 분획물 또는 이 분획물로부터 유래된 리퀴리티게닌〔Liquiritigenin〕을 유효성분으로 함유하는 이담작용 및 담즙정체성 간질환의 예방 및 치료용 조성물

    公开(公告)号:KR1020100039755A

    公开(公告)日:2010-04-16

    申请号:KR1020080098838

    申请日:2008-10-08

    CPC classification number: A61K36/484 Y10S514/877 Y10S514/894

    Abstract: PURPOSE: A composition containing Glycyrrhizae radix-process fraction or liquiritigenin derived from the fraction is provided to enhance expression of transport protein gene and to prevent and treat liver diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases contains Glycyrrhizae radix-processed fraction or liquiritigenin derived from the same. A method for preparing the Glycyrrhizae radix fraction comprises: a step of extracting Glycyrrhizae radix with non-polar solvent and removing non-polar component to obtain Glycyrrhizae radix extract; a step of hydrolyzing liquiritigenin and neutralizing to obtain Glycyrrhizae radix hydrolysate; and a step of washing the hydrolysate with water to remove saccharide and salt.

    Abstract translation: 目的:提供一种含有甘草根组分或衍生自该级分的甘草素的组合物,以增强转运蛋白基因的表达并预防和治疗肝脏疾病。 构成:用于预防和治疗肝脏疾病的药物组合物含有甘草根加工级分或衍生自其的甘草素。 一种制备甘草组分的方法,包括:用非极性溶剂提取甘草,除去非极性成分得到甘草提取物的步骤; 水解甘草素并中和获得甘草碱水解物的步骤; 以及用水洗涤水解物以除去糖和盐的步骤。

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