公开(公告)号：KR101148755B1

公开(公告)日：2012-05-22

申请号：KR1020090126110

申请日：2009-12-17

Applicant: 서울대학교산학협력단

Inventor： 김용식 ,  안용민 ,  이규영 ,  김세현

IPC: C12N15/11 ,  C12Q1/68

Abstract: PURPOSE: A SNP(single nucleotide polymorphism) of DUSP6 gene related to bipolar disorder is provided to screen a therapeutic agent for bipolar disorder. CONSTITUTION: A SNP(single nucleotide polymorphism) is a polynucleotide having 10 or more serial DNA sequence derived from DNA sequence of sequence number 1 containing 1524th base which is G; and a polynucleotide having 10 or more serial DNA sequence derived from the DNA sequence of sequence number 1 containing 2683th base which is C; or a complementary polynucleotide thereof. A probe for diagnosing bipolar disorder contains the polynucleotide. A microarray for diagnosing bipolar disorder contains the probe. A kit for diagnosing bipolar disorder contains the polynuelcotide. A method for diagnosing bipolar disorder comprises: a step of preparing a nucleic acid sample from a test sample; and a step of determining nucleotide sequence of SNP.