Abstract:
본 발명은 대추, 복분자, 애엽, 황금 및 Rg2 강화 홍삼을 유효성분으로 함유하는 골다공증 예방, 개선 또는 치료를 위한 조성물에 관한 것이다. 더욱 상세하게는, TNF-α 및 IL-1β를 감소시키고, iNOS 및 MMPs의 발현을 억제하며, 파골세포의 분화를 억제하고, 조골세포 분화인자의 발현을 증가시키며, 골다공증 유도 마우스 모델에서 골밀도를 증가시키는 효능이 있는 골다공증 예방, 개선 또는 치료를 위한 조성물에 관한 것이다.
Abstract:
The present invention relates to a composition having anti-oxidant, anti-inflammatory, and skin whitening effects and containing a kudzu aerial part extract as an active ingredient. More specifically, the present invention relates to a composition which can promote anti-oxidant, anti-inflammatory, and skin whitening effects without side effects using natural materials. The composition which can promote an anti-oxidant effect according to the present invention concentration-dependently exhibits an anti-oxidant effect as a result of a DPPH experiment. Moreover, the composition which can promote an anti-inflammatory effect according to the present invention can control the generation of NO and the expression of iNOS and COX-2. In addition, the composition which can promote a skin whitening effect according to the present invention can prevent melanin synthesis in cells, prevent melanin synthesis caused by α-MSH, inhibit melanin accumulation, control the expression of melanin synthesis enzymes and factors related to the synthesis, and improve skin whitening effect even at an in vivo level.
Abstract:
PURPOSE: A composition for prevention and treatment of rheumatoid arthritis and osteoarthritis is provided to suppress pain and inflammation of common symptoms in acute and chronic arthritis, and to improve exercise barrier which is a symptom of the chronic arthritis. CONSTITUTION: A composition for prevention and treatment of rheumatoid arthritis comprises an active ingredient mixed with: 350-450 wt% of Kalopanacis Cortex; 350-450 wt% of Chinese quince; 50-150 wt% of first extract which is extracted from Pulvis Aconiti Tuberis Purificatum; 150-250 wt% of Raphani Semen; and 50-150 wt% of second extract which is extracted from Atractylodis Rhizoma. The extract shows an effect which does not have chytotoxin to synoviocyte and chondrocyte. The extract shows effects of improving exercise barrier, and arthritic and analgesia. The extraction solvent for the first extract is 40-60 wt% of alcohol, and the extraction solvent for the second extract is water. [Reference numerals] (AA) Alleviating pain effect