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公开(公告)号：KR1020150111554A
公开(公告)日：2015-10-06
申请号：KR1020140034941
申请日：2014-03-25
Applicant: 전남대학교산학협력단
IPC: A61K31/737 , A61K31/717 , A61K31/728 , A61P43/00
CPC classification number: A61K31/717 , A61K9/06 , A61K31/728 , A61K31/737 , A61K2121/00 , A61K2300/00
Abstract: 본발명은황산콘드로이친을함유한유착방지용조성물과이의제조방법에관한것으로서, 더욱상세하게는하이드로겔형태로사용이간편하고독성이없으면서도황산콘드로이친을함유시켜생체조직간의유착을효과적으로방지할수 있는유착방지용조성물과이의제조방법에관한것이다.
Abstract translation: 本发明涉及含有硫酸软骨素的抗粘连组合物及其制造方法，更具体地说，涉及由于呈水凝胶形式而无毒性而易于使用的抗粘连组合物，其含有硫酸软骨素 ，从而有效地防止生物组织之间的粘附及其制造方法。
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公开(公告)号：KR1020150056725A
公开(公告)日：2015-05-27
申请号：KR1020130139308
申请日：2013-11-15
Applicant: 전남대학교산학협력단 , (주)태봉
CPC classification number: A61K47/38 , A61K9/06 , A61K31/351 , A61K47/32 , A61K2121/00
Abstract: 본발명은알로인을함유하는하이드로겔기반의창상피복제용조성물과이의제조방법에관한것으로서, 더욱상세하게는폴리비닐알콜과카르복시메틸셀룰로오스로조성된하이드로겔에알로인을첨가하여창상보호및 치료에효과적인창상피복제용조성물과이의제조방법에관한것이다. 본발명의알로인을함유하는하이드로겔기반의창상피복제용조성물은하이드로겔에알로인(aloin)이함유한다. 그리고본 발명의알로인을함유하는하이드로겔기반의창상피복제용조성물의제조방법은폴리비닐알콜과카르복시메틸셀룰로오스(carboxymethyl cellulose)가용해된혼합용액을수득하는제 1단계와, 혼합용액에알로인(aloin)을첨가하는제 2단계와, 알로인이첨가된상기혼합용액을겔화시키는제 3단계를포함한다.
Abstract translation: 本发明涉及一种含有芦荟的水凝胶基伤口涂料组合物及其制备方法，更具体地说，涉及一种通过将芦荟添加到由聚乙烯醇和羧甲基纤维素组成的水凝胶中以有效地保护和治疗伤口而制备的伤口涂料组合物， 及其制备方法。 在含有芦荟的伤口涂层组合物中，将芦荟加入到氢化物中。 含有芦荟的制备方法水凝胶基伤口涂层组合物包括：获得其中溶解有聚乙烯醇和羧甲基纤维素的混合溶液的第一步骤; 向混合溶液中加入芦荟的第二步; 以及从添加有芦荟的混合溶液形成凝胶的第三步骤。
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公开(公告)号：KR1020140114622A
公开(公告)日：2014-09-29
申请号：KR1020130029119
申请日：2013-03-19
Applicant: 전남대학교산학협력단
Abstract: The present invention provides a method for producing various kinds of low toxic hydrogel using natural polymers and hydrogel produced through the same, wherein the low toxic hydrogel has a rapid absorbing speed and a high absorbing amount. Alginic acid hydrogel and k-carageenan/karaya gum hydrogel exhibiting rapid swelling properties can be applied to a diaper or a hygiene product. CMC hydrogel and amide pectin hydrogel having a slow swelling speed but exhibiting a high horizontal swelling degree can be utilized as a vegetation mat. The hydrogel produced in the present invention can be applied in various fields by producing pores and adjusting a composition rate using various natural polymers.
Abstract translation: 本发明提供了使用天然聚合物和通过其制备的水凝胶来生产各种低毒水凝胶的方法，其中低毒水凝胶具有快速吸收速度和高吸收量。 表现出快速溶胀性能的海藻酸水凝胶和k-角叉菜胶/刺梧桐树胶水凝胶可以应用于尿布或卫生用品。 具有缓慢溶胀速度但具有高水平膨胀度的CMC水凝胶和酰胺果胶水凝胶可用作植被垫。 本发明中生产的水凝胶可以通过使用各种天然聚合物产生孔隙和调节组成比来应用于各种领域。
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公开(公告)号：KR101310614B1
公开(公告)日：2013-09-24
申请号：KR1020100122102
申请日：2010-12-02
Applicant: 전남대학교산학협력단 , (주) 켐포트
Abstract: 본 발명은 소수성 불포화지방산과 수용성 키토산의 정전기적 상호작용(electrostatic interaction)을 이용한 나노입자 제조와 종양모델 마우스를 이용한 EPR(enhanced permeability retention: 종양부위에 흡수되는 나노입자의 양과 그 위치에 머무는 시간을 향상시키는 효과)실험을 통해 종양 조직에 효과적으로 축적되며 불포화지방산의 도입으로 암세포에 대한 치료 특성을 갖는 주사제용 및 경구용 항암제의 제조에 관한 새로운 발명이다. 본 발명의 나노입자는 불포화지방산의 캡슐화가 가능하고 불포화지방산의 악취와 산패를 막음으로써 식품-의약품으로의 개발을 가능케 하는 새로운 발명이다. 소수성 불포화지방산과 수용성 키토산의 나노입자는 수용액상에서 구의 형태를 가지며 110-330nm의 크기를 형성한다. 광학영상(optical image)을 위해 제조된 나노입자에 Cy7을 표지시켜 동물실험을 통하여 확인하였다.
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公开(公告)号：KR1020120061163A
公开(公告)日：2012-06-13
申请号：KR1020100122102
申请日：2010-12-02
Applicant: 전남대학교산학협력단 , (주) 켐포트
CPC classification number: A61K9/5161 , A61K47/61 , B82Y5/00 , B82Y40/00 , G01N33/54346 , G01N33/574
Abstract: PURPOSE: An unsaturated fatty acid-chitosan composite which forms self-assembled nano-particles and a manufacturing method thereof are provided to manufacture the self-assembled nano-particles without adding emulsifier by using electrostatic interaction between water-soluble chitosan and unsaturated fatty acid. CONSTITUTION: An unsaturated fatty acid-chitosan composite which forms self-assembled nano-particles comprises water-soluble chitosan which is represented by chemical formula 1 and unsaturated fatty acid which is combined by applying electrostatic interaction to the water-soluble chitosan. In the chemical formula 1, n indicates an integer of 10-10,000. An end part of the unsaturated fatty acid is esterified by combining end part of carboxyl group with alkyl group having 1-10 carbons. Oxygen of the ester takes part in the electrostatic interaction.
Abstract translation: 目的：提供一种形成自组装纳米颗粒的不饱和脂肪酸 - 壳聚糖复合物及其制备方法，通过使用水溶性壳聚糖和不饱和脂肪酸之间的静电相互作用，不加入乳化剂来制造自组装纳米颗粒。 构成：形成自组装纳米颗粒的不饱和脂肪酸 - 壳聚糖复合物包括由化学式1表示的水溶性壳聚糖和通过向水溶性壳聚糖施加静电相互作用而组合的不饱和脂肪酸。 在化学式1中，n表示10〜10000的整数。 通过将羧基的末端与具有1-10个碳的烷基结合，将不饱和脂肪酸的末端部分酯化。 酯的氧气参与静电相互作用。
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Patent Agency Ranking
公开(公告)号：KR1020110088702A
公开(公告)日：2011-08-04
申请号：KR1020100008326
申请日：2010-01-29
Applicant: 전남대학교산학협력단 , (주) 켐포트
CPC classification number: A61K9/1271 , A61K9/1277 , A61K31/202 , A61K47/36 , Y10S514/857
Abstract: PURPOSE: An EPA-containing liposome which is coated with thiol chitosan and a method for preparing the same are provided to maximize stability, efficiency, and absorption rate. CONSTITUTION: A method for preparing EPA-containing liposome coated with thiol chitosan comprises: a step of adding a volatile organic solvent to a mixture to prepare a phospholipid solution; a step of evaporating and concentrating the phosphlipid solution to prepare a thin film; a step of adding thiol chitosan solution to the thin film; and a step of hydrating thin film to prepare liposome.
Abstract translation: 目的：提供涂有巯基壳聚糖的含EPA脂质体及其制备方法，以使稳定性，效率和吸收速度最大化。 构成：包含硫醇壳聚糖的含EPA脂质体的制备方法包括：向混合物中加入挥发性有机溶剂以制备磷脂溶液的步骤; 蒸发并浓缩磷脂溶液以制备薄膜的步骤; 向薄膜中添加硫醇壳聚糖溶液的步骤; 以及水合薄膜以制备脂质体的步骤。
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公开(公告)号：KR1020100111423A
公开(公告)日：2010-10-15
申请号：KR1020090029851
申请日：2009-04-07
Applicant: 전남대학교산학협력단 , (주) 켐포트
IPC: A61K6/08
Abstract: PURPOSE: A method for manufacturing an UV protecting agent of nano capsule containing eicosapentaenoic acid(EPA) and titanium dioxide sol is provided to ensure skin dispersibility and to completely block UV. CONSTITUTION: A method for manufacturing an UV protecting agent comprises: a step of completely dissolving titanium isopropoxide and anhydrous ethanol at room temperature; a step of dropping the mixture to distilled water to obtain titanium dioxide sol; a step of dissolving chitosan into an acetic acid solution and dispersing the titanium dioxide sol and eicosapentaenoic acid to ethanol; a step of dropping into chitosan solution and stirring to obtain nanoparticles; a step of washing and drying nanoparticles; a step of separating solution and nanoparticles; and a step of storing in a freeze-drier and diluting in a small amount of water.
Abstract translation: 目的：提供含有二十碳五烯酸（EPA）和二氧化钛溶胶的纳米胶囊的紫外线防护剂的制造方法，以确保皮肤分散性和完全阻止紫外线。 构成：紫外线防护剂的制造方法包括：在室温下完全溶解异丙醇钛和无水乙醇的工序; 将混合物滴加到蒸馏水中以获得二氧化钛溶胶的步骤; 将壳聚糖溶解在乙酸溶液中并将二氧化钛溶胶和二十碳五烯酸分散到乙醇中的步骤; 滴入壳聚糖溶液并搅拌以获得纳米颗粒的步骤; 洗涤和干燥纳米颗粒的步骤; 分离溶液和纳米颗粒的步骤; 以及在冷冻干燥机中储存并稀释少量水的步骤。
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公开(公告)号：KR101769019B1
公开(公告)日：2017-08-17
申请号：KR1020170037860
申请日：2017-03-24
Applicant: 전남대학교산학협력단
IPC: A61K35/60 , A61K31/715 , A61K33/42 , A61K31/195 , A61L27/54
CPC classification number: A61K35/60 , A61K31/195 , A61K31/715 , A61K33/42 , A61L27/54 , A61L2300/30 , A61L2430/02
Abstract: 본발명은황다랑어껍질추출물, 젤란검, 인산칼슘계무기물및 인산완충식염수를포함하는골재생유도조성물에관한것이다또한, 상기골재생유도조성물로제조되는골재생유도차폐막및 이의제조방법에관한것이다.
Abstract translation: 本发明涉及一种黄鳍金枪鱼皮肤提取液，结冷胶，本发明涉及一种包括磷酸钙矿物和磷酸盐缓冲盐水另外一个骨再生组合物，所述骨再生屏蔽膜和制造方法制成的骨再生的组合物的 。
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公开(公告)号：KR101624511B1
公开(公告)日：2016-05-26
申请号：KR1020160005115
申请日：2016-01-15
Applicant: 전남대학교산학협력단
Abstract: 본발명은젤란검, 황산콘드로이친및 겔화제를포함하여기존유착방지제의문제점인빠른분해, 낮은점도및 낮은강도를개선하고, 생체조직간의유착을방지하는유착방지제조성물및 이를포함하는유착방지제제조방법에관한것이다.
Abstract translation: 本发明涉及包含结冷胶，硫酸软骨素和用于改善快速分解，低粘度和低强度的胶凝剂的防粘连组合物，其是存在的抗粘合剂的问题，并且用于防止组织之间的粘附。 本发明还涉及一种制造包含该抗粘剂的防粘剂的方法。
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