公开(公告)号：KR1020170111095A

公开(公告)日：2017-10-12

申请号：KR1020160035892

申请日：2016-03-25

Applicant: 한국과학기술원

Inventor： 강창원 ,  김세원

IPC: A61K38/40 ,  A61K9/00 ,  A61K9/02

Abstract: 본발명은트랜스페린을유효성분으로함유하는허혈성망막병증예방및 치료용조성물에관한것으로, 본발명에따른허혈성망막병증예방및 치료용조성물은망막신경절세포의세포사멸을방지하여허혈성망막병증을예방및 치료하는효과가탁월하여, 허혈성망막병증예방및 치료에유용하다.

公开(公告)号：KR101157526B1

公开(公告)日：2012-06-22

申请号：KR1020110094918

申请日：2011-09-20

Applicant: 한국과학기술원 ,  서울대학교산학협력단

Inventor： 강창원 ,  김은준 ,  김재원 ,  김은진 ,  원혜정 ,  마원 ,  조수철

IPC: C12Q1/68 ,  C12N15/12

CPC classification number: C12Q1/6883 ,  C12Q2600/156 ,  G01N21/76 ,  C12Q1/6844

Abstract: PURPOSE: A composition for diagnosing risk of developing ADHD and a kit are provided to classify a risk group of developing ADHD and to prevent ADHA. CONSTITUTION: A composition for diagnosing ADHA contains a polynucleotide of rs550818 SNP in GIT gene having24926101th C/T base of 17th human chromosome. The composition contains likage disequilibrium site near the rs550818 SNP. A method for predicting risk of developing ADHD comprises: a step of isolating DNAs from a biological sample of a subject; a step of identifying the rs550818 SNP base at 24926101th base site in 17th human chromosome; and a step of determining high risk of developing ADHD in case that the rs550818 SNP allele is C/T.

Abstract translation: 目的：提供一种用于诊断发展中ADHD风险的组合物和一个试剂盒，用于分类发展中的ADHD的风险组并防止ADHA。 构成：用于诊断ADHA的组合物含有GIT基因中rs550818 SNP的多核苷酸，其具有第17个人染色体的第24926101个C / T碱基。 该组合物包含rs550818 SNP附近的可能不平衡位点。 用于预测发展中的ADHD的风险的方法包括：从受试者的生物样品中分离DNA的步骤; 在第17个人类染色体的第24926101个碱基位点鉴定rs550818 SNP碱基的步骤; 并且在rs550818 SNP等位基因为C / T的情况下确定发生ADHD的高风险的步骤。