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公开(公告)号：KR1020140012578A
公开(公告)日：2014-02-03
申请号：KR1020120135556
申请日：2012-11-27
Abstract: A method for generating a tomography image and an apparatus for generating a tomography image determine at least one basic pattern of a spatial light modulator for modulating the phase of incident light according to a pixel arrangement pattern; perform spatial shift modulation for moving arrangement of pixels as many as the set number in a vertical or a horizontal direction with respect to the basic pattern; generate tomography images for the respective shift patterns of the basic pattern by using spectrum signals of rays collected from rays which penetrate through the spatial optical modulator and enter a target body; select one pattern for generating the clearest tomography image among the shift patterns of the basic pattern based on the generated tomography images; and generate the final tomography image on the target body by using the selected pattern. [Reference numerals] (110) Optical output part; (120) Spatial optical modulator; (130) Modulation controller; (140) Detection part; (150) Image generating part; (160) Image processing part
Abstract translation: 一种用于产生断层摄影图像的方法和用于产生断层摄影图像的装置确定用于根据像素布置图案调制入射光的相位的空间光调制器的至少一个基本图案; 执行空间移位调制，用于相对于基本图案在垂直或水平方向上移动与设定数量一样多的像素的排列; 通过使用从穿过空间光学调制器并进入目标体的射线收集的光线的频谱信号，生成基本图案的各个移位图案的断层图像; 基于生成的断层摄影图像，选择用于在基本图案的移位模式中生成最清晰的断层图像的一个图案; 并通过使用所选择的图案在目标体上产生最终断层图像。 （附图标记）（110）光输出部; （120）空间光调制器; （130）调制控制器; （140）检测部件; （150）图像生成部; （160）图像处理部分
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公开(公告)号：KR1020130125596A
公开(公告)日：2013-11-19
申请号：KR1020120049239
申请日：2012-05-09
Applicant: 한국과학기술원
CPC classification number: G02B21/244 , G02B7/38 , G02B21/367 , H04N5/23212 , H04N5/235
Abstract: The present invention relates to a focal surface stabilizing device of a microscope using a long distance focusing method and the non-linear transformation of a point spread function and a method thereof which is one method for stabilizing a focal surface at a nanometer scale. The microscope focal stabilizing method includes a step of bring a reference light source into focus on a cover glass surface; a step of transforming the point spread function of the reference light source into a non-linear shape; and a step of calculating a focal function of the reference light source. [Reference numerals] (110) Step of focusing a reference light source on a cover glass surface;(120) Step of converting the point spread function of the reference light source into a non-linear shape;(130) Step of calculating the focus function of the reference light source;(140) Step of controlling feedbacks;(AA) Start;(BB) End
Abstract translation: 本发明涉及一种使用长距离聚焦方法和点扩散函数的非线性变换的显微镜的焦面稳定装置及其方法，该方法是用于稳定纳米尺度的焦面。 显微镜聚焦稳定化方法包括将参考光源聚焦在盖玻璃表面上的步骤; 将参考光源的点扩散函数变换为非线性形状的步骤; 以及计算参考光源的焦点功能的步骤。 （110）将参考光源聚焦在盖玻璃表面上的步骤;（120）将参考光源的点扩展函数转换为非线性形状的步骤;（130）计算焦点的步骤 参考光源的功能;（140）反馈控制步骤;（AA）开始;（BB）结束
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公开(公告)号：KR101252938B1
公开(公告)日：2013-04-12
申请号：KR1020110032783
申请日：2011-04-08
Applicant: 한국과학기술원
CPC classification number: G01N21/6458
Abstract: 본 발명의 실시예들은 초고해상도 현미경 시스템 및 그 시스템을 이용한 영상 획득 방법에 관한 것으로, 불규칙적인 산란광을 입사하여 인접한 공간에서의 상관관계를 적게 만들어 이러한 특성을 이용하여 대상 물체를 고해상도로 관찰할 수 있는 방법 및 그 현미경 시스템에 관련된다. 본 발명의 실시예에 의하면, 세포 연구에 유용한 형광 현미경의 회절한계를 극복할 수 있고, 나노미터급 초고수준의 해상도의 영상을 얻을 수 있다.
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公开(公告)号：KR100783584B1
公开(公告)日：2007-12-07
申请号：KR1020060079000
申请日：2006-08-21
Applicant: 한국과학기술원
CPC classification number: G02B21/22 , G02B21/362 , G02B27/2285
Abstract: A 2.5D microscope system is provided to effectively obtain 3D information of a sample by inserting an off-axis stop to a conventional microscope system. A 2.5D microscope system includes a mount(6), an objective lens(5), an eye lens(8), a CCD(Charge Coupled Device) camera(2) and an off-axis stop. The mount supports a sample(9). The objective lens is used to observe the sample on the mount. The eye lens and the CCD camera receive light from the sample through a beam splitter(3). The light from the sample passes by the objective lens. The off-axis stop is applied between the objective lens and the beam splitter and receives the light from the sample. A hole is formed on the off-axis stop, which is arranged on the objective lens and derailed from an optical axis.
Abstract translation: 提供2.5D显微镜系统，通过将偏轴止挡插入到常规的显微镜系统中来有效地获得样品的3D信息。 2.5D显微镜系统包括安装件（6），物镜（5），眼睛透镜（8），CCD（电荷耦合器件）照相机（2）和离轴止动件。 安装座支撑样品（9）。 物镜用于观察底座上的样品。 眼镜和CCD相机通过分束器（3）从样品接收光。 来自样品的光通过物镜。 离轴止动器被施加在物镜和分束器之间并接收来自样品的光。 在离轴止动件上形成有一个孔，它设置在物镜上并从光轴脱轨。
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Patent Agency Ranking
公开(公告)号：KR101495136B1
公开(公告)日：2015-02-25
申请号：KR1020080113839
申请日：2008-11-17
IPC: G06T15/00
CPC classification number: G06T11/006 , G06T2211/424 , G06T2211/436
Abstract: 2차원 영상으로부터 3차원 영상을 재구성하는 방법 및 장치가 제공된다. 제한된 각도에서 엑스선(x-ray) 발생 튜브로부터 재구성되는 3차원 데이터를, 각 화소별로 반복적으로 갱신하고, 복원하기 위해서 투영된 데이터의 각 화소들 중에서 중앙값(median)을 선택하며, 재투영된 영상 및 나머지 영상을 이용한 탐색 방향 가중치를 이용하여 역투영하여, 복원 데이터의 희소성(sparsity) 구속 조건과 L1 놈 충실성(fidelity)이 있는 데이터 조건을 만족하는 3차원 영상을 재구성할 수 있다.
엑스선(x-ray), 영상 재구성(tomosynthesis), L1 놈 충실성(fidelity) 데이터, 데이터의 희소성(sparsity)-
公开(公告)号：KR1020140026992A
公开(公告)日：2014-03-06
申请号：KR1020120129100
申请日：2012-11-14
Abstract: Disclosed is an apparatus for generating tomography images having a modulation and calibration device and a method of operating the same. The tomography image-generating apparatus according to an embodiment of the present invention comprises: a light source unit to emit light used for irradiating a subject; an optical control unit to control the propagating direction of light; an optical coupler to divide/combine incident light; a plurality of optical systems optically connected to the optical coupler; and an optical modulation and calibration device used for the light irradiated to the subject. The modulation and calibration device can be provided between the optical control unit and the coupler. Also, the modulation and calibration device can be included in the optical system irradiating the subject among the plurality of optical systems. The optical modulation device can modulate only incident light reflected to the subject. [Reference numerals] (60) Subject (organ)
Abstract translation: 公开了一种用于产生具有调制和校准装置的断层摄影图像的装置及其操作方法。 根据本发明实施例的断层摄影图像产生装置包括：发射用于照射对象的光的光源单元; 光控制单元，用于控制光的传播方向; 用于分离/组合入射光的光耦合器; 光学连接到光耦合器的多个光学系统; 以及用于照射到被摄体的光的光学调制和校准装置。 调制和校准装置可以设置在光学控制单元和耦合器之间。 此外，调制和校准装置可以包括在照射多个光学系统中的对象的光学系统中。 光调制装置可以仅调制反射到被摄体的入射光。 （附图标记）（60）主题（器官）
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公开(公告)号：KR1020140012586A
公开(公告)日：2014-02-03
申请号：KR1020130069201
申请日：2013-06-17
CPC classification number: G06T11/003 , G01N23/046 , G06T5/002 , G06T5/10 , G06T2207/10101 , G06T2211/416
Abstract: A tomography image generating method and a tomography image generating apparatus performing the method according to the present invention: perform a depth scan at one spot on a surface of an object using an incident ray at the object from a spatial optical modulator; obtain depth scan data for each of multiple patterns of the spatial optical modulator by repeating the depth scan at the spot for each of the patterns; form a matrix R representing a vector space based on a correlation between signal values of the depth scan data for each of the patterns; perform a predetermined matrix decomposition of the matrix R; divide the vector space represented by the sum of subspace components by the matrix decomposition into a noise subspace and a signal subspace; reconstruct a vector space using components of the signal subspace and/or components of the noise subspace; and generate a tomography image based on the reconstructed vector space. [Reference numerals] (110) Optical output unit; (120) Spatial optical modulator; (130) Modulation controller; (140) Depth scan unit; (150) Data obtaining unit; (160) Signal processing unit; (170) Image generating unit
Abstract translation: 执行本发明的方法的断层摄影图像生成方法和断层摄影图像生成装置：使用来自空间光学调制器的物体的入射光线在物体表面的一个点进行深度扫描; 通过对于每个图案重复在点处的深度扫描来获得空间光学调制器的多个图案中的每一个的深度扫描数据; 基于每个图案的深度扫描数据的信号值之间的相关度，形成表示向量空间的矩阵R; 执行矩阵R的预定矩阵分解; 将通过矩阵分解的子空间分量的和表示的向量空间划分为噪声子空间和信号子空间; 使用信号子空间和/或噪声子空间的分量的分量来重建向量空间; 并且基于重建的向量空间生成断层摄影图像。 （附图标记）（110）光输出单元; （120）空间光调制器; （130）调制控制器; （140）深度扫描单位; （150）数据获取单元 （160）信号处理单元; （170）图像生成单元
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公开(公告)号：KR1020120114933A
公开(公告)日：2012-10-17
申请号：KR1020110032783
申请日：2011-04-08
Applicant: 한국과학기술원
CPC classification number: G01N21/6458
Abstract: PURPOSE: An ultra resolution microscope system and an image obtaining method using the same are provided to obtain an image in ultra resolution of a nanometer degree by using an irregular pattern and an alignment signal processing technique. CONSTITUTION: A scattering pattern generator(110) passes transmitted light through a scattering unit to photograph fluorescent light sources of an object. An incident optical system(120) inserts a scattering pattern generated by one or more optical lenses into a specimen. A fluorescent optical image system(130) passes the inserted scattering pattern through one or more excitation filters and fluorescent filters in order. [Reference numerals] (110) Scattering pattern generator; (120) Incident optical system; (130) Fluorescent optical image system; (140) Image restoration algorithm
Abstract translation: 目的：提供一种超分辨率显微镜系统和使用其的图像获取方法，以通过使用不规则图案和对准信号处理技术来获得超分辨率的纳米级的图像。 构成：散射图案发生器（110）将透射光通过散射单元以照射物体的荧光光源。 入射光学系统（120）将由一个或多个光学透镜产生的散射图案插入到样本中。 荧光光学图像系统（130）依次将经插入的散射图案通过一个或多个激发滤光片和荧光滤光片。 （附图标记）（110）散射图案发生器; （120）入射光学系统; （130）荧光光学图像系统; （140）图像恢复算法
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公开(公告)号：KR1020100054973A
公开(公告)日：2010-05-26
申请号：KR1020080113839
申请日：2008-11-17
IPC: G06T15/00
CPC classification number: G06T11/006 , G06T2211/424 , G06T2211/436
Abstract: PURPOSE: A method and an apparatus for regenerating a three-dimensional image from a two-dimensional image are provided to improve a noise removal effect compared with a linear filtering method by processing images through a non-linear filtering method according to a median value. CONSTITUTION: A recovery image generator(310) creates a three-dimensional recovery image through reverse projection using a pixel value corresponding to a median value among pixel values of images. The images are created by the two-dimensional projection of a target to be three-dimensionally recovered. A re-projection image generator(320) creates a two-dimensional re-projected image through the re-projection of the three-dimensional recovered image. A residual image forming part(330) constitutes a residual image according to the difference between the projected image and the two-dimensional re-projected image.
Abstract translation: 目的：提供一种用于从二维图像再生三维图像的方法和装置，以通过根据中值的非线性滤波方法处理图像而与线性滤波方法相比提高噪声去除效果。 构成：恢复图像生成器（310）通过使用与图像的像素值之间的中值对应的像素值的反投影来创建三维恢复图像。 图像通过三维恢复的目标的二维投影来创建。 再投影图像生成器（320）通过三维恢复图像的重新投影产生二维再投影图像。 残留图像形成部（330）根据投影图像与二维再投影图像之间的差构成残差图像。
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