Abstract:
본원발명은 독립된 미세 구조물 내에서 동물 세포를 배양하는 기술에 관한 것으로, 상부면에 금속으로 가공된 미세 열선을 구비하는 하부 유리 기판, 액체 저장 공간 및 고체 저장 공간을 상기 하부 유리 기판의 미세 열선에 대응하는 위치에 형성하고, 상기 액체 저장 공간 및 상기 고체 저장 공간에 연결되어 각각 발생한 기체가 이동할 수 있는 기체 이동 채널을 구비하여 상기 하부 유리 기판 상부에 부착된 PDMS 막, 상기 PDMS 막의 상기 기체 이동 채널의 상부에 부착되어 상기 발생한 기체가 통과할 수 있는 기체 투과성 PDMS 박막, 배양액을 저장할 수 있는 배양액 저장 공간을 구비하여, 상기 PDMS 박막의 상부에 부착되는 PDMS 막, 하부면에 PDMS 막으로 덮힌 미세 열선을 구비하여, 미세 구조물 내에서 동물 세포의 배양에 필요한 기체를 자체 공급할 뿐만 아니라 배양액의 온도를 조절할 수 있는 효과가 있다. PDMS(polydimethylsiloxane), 배양액, 미세열선
Abstract:
A microfluidic control device is provided to perform the minute control of fluid sample by bond of natural flow and forced flow, entire change or strong washing. A microfluidic control device(100) comprises a first substrate and a second substrate. The first substrate comprises sensing electrode(212), heaters and temperature sensors. The second substrate has fluid inlet(112), fluid inlet chamber unit(114), flow path unit(116), reaction chamber unit(118), valve unit, pump unit, and waste water chamber unite(130). The reaction chamber unit corresponds to the sensing electrode. The valve unit corresponds to one of heaters and temperature sensors. A method for operating the microfluidic control device comprises: a step of injecting fluid sample; a step of transferring the fluid sample to the sensing electrode; a step of stopping the flow of fluid sample; and a step of discarding the fluid sample.
Abstract:
A biochip reader apparatus is provided to obtain more accurate optical sensing results from a biochip or strip chip by using three color light sources in the bio-MEMS(micro-electromechanical systems), and transmit the reading results or receive information at any time and place. A biochip reader apparatus comprises: a light-emitting unit(101) containing a three color light-emitting device; a receiving unit(102) for receiving a light reflected by, bended by or penetrated through a biochip to be analyzed from the light-emitting unit, and converting into the electrical signal; a treating unit for operating the light-emitting unit in a switching type when the biochip is mounted, and analyzing the received electrical signal; a memory unit for storing a program operated by the treating unit and temporally storing the analysis results treated by the treating unit; and a display unit for displaying the analysis results.
Abstract:
A micro filtration device for separation of blood plasma is provided to separate the blood plasma from the whole blood by itself without the help of external equipment like a syringe pump. A micro filtration device for separation of blood plasma includes a whole blood inlet(120), a blood plasma outlet, a blood plasma storing chamber(150), a paper filter(200) and a micro-structure(190). The blood plasma outlet is used to discharge the blood plasma separated from the flowing whole blood to the outside. The paper filter is formed between the whole blood inlet and the blood plasma storing chamber, and separates the blood plasma from the whole blood. The micro-structure is formed inside the blood storing chamber to move the blood plasma.
Abstract:
A microfluidic device for equalizing multiple microfluid flows in a chamber, which enables the joined multiple fluids to flow in parallel within the chamber when fluids transferred through different channels are joined and pass through a chamber with varying cross-section, and a microfluidic network using the same are provided. In a microfluidic device using a capillary phenomenon, a microfluidic device for equalizing multiple microfluid flows in a chamber comprises: a plurality of channels(610,615) which are formed between an upper substrate and a lower substrate to transfer fluids, and which have fluid injection ports(310,320) formed at one sides thereof to inject the fluids, and fluid stopping faces(630,635) formed at the other sides thereof to stop the movement of the fluids; a pressure control channel(600) formed such that the fluid injection ports are connected to the pressure control channel to remove pressure differences between the fluids injected into the respective channels; a fluid joining part(670) joining the fluids passing through the respective fluid stopping faces; and a chamber on which strong hydrophilic surfaces(410) with a predetermined width and weak hydrophilic surfaces(420) with a predetermined width are alternately formed in fluid transfer directions so as to transfer the fluids joined in the fluid joining part in a uniform and parallel manner.
Abstract:
본 발명은 제 1 전극과 제 2 전극 사이에 게재된 전하를 띠고 있는 생체분자를 포함하여, 두 전극 사이의 전하량의 차이 변화시킴에 따라 측정되는 커패시턴스의 변화값을 측정하여 생체분자간의 화학적 결합정도를 분석하는 분석장치를 제공한다. 두 전극사이의 거리를 마이크로미터 원리를 이용해서 조절가능케 함으로써 편리성를 높이는 장점을 제공한다. 커패시턴스, 생체분자, DNA, SNP
Abstract:
본 발명은 미소 유체 제어소자 및 미소 유체의 제어 방법에 관한 것으로, 자연적인 유체의 유동과 용액 투입만으로 미소량의 유체를 제어한다. 용액 투입에 따른 표면장력의 변화에 의해 모세관의 압력장벽이 제거되도록 하므로써 미소 유체의 이동, 합류, 혼합 및 시간지연이 이루어진다. 정지밸브에 의해 유체가 정지된 상태에서 용액을 투입하여 정지밸브에 정지된 유체의 계면과 만나도록 하므로써 정지밸브의 기능이 상실되어 유체의 이동, 합류 및 혼합이 이루어진다. 본 발명의 유체 제어 방법은 생화학적 반응을 위한 미소 유체 제어소자에 응용될 수 있으며, 용액의 투입에 따른 모세관력의 변화만을 이용하므로 소자의 구조가 간단하다.
Abstract:
PURPOSE: A device for controlling fluid using surface tension is provided, thereby removing additional pump and electric power supply from the device, so that the device can be minimized and portable, while reducing the production costs, and increasing production yield. CONSTITUTION: A device for controlling fluid using surface tension comprises at least one of fluid storage chambers(100, 102); at least one reaction chamber(112); at least one fluid discarding chamber(114); at least one fluid channel(108) connecting the storage chamber, the reaction chamber and the discarding chamber; at least one fluid flow delaying portion(110) which is positioned within the fluid channel and delays the fluid flow by the surface tension; and at least one of fluid flow stop valves(104, 106) which are positioned within the fluid channel and stopping the fluid flow, wherein the fluid flow is automatically generated by the surface tension.