2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS
    18.
    发明公开
    2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 审中-公开
    2-AMIN 1H咪唑环系统和方法

    公开(公告)号:EP1784180A2

    公开(公告)日:2007-05-16

    申请号:EP05794980.2

    申请日:2005-09-01

    CPC classification number: C07D471/04 C07D471/14

    Abstract: 1H-Imidazo ring systems (e.g., imidazopyridines, imidazoquinolines, imidazonaphthyridines, 6,7,8,9-tetrahydro imidazoquinolines and imidazonaphthyridines) with an amino substituent at the 2-position, pharmaceutical compositions containing these compounds, methods of making the compounds, intermediates, and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.

    Abstract translation: 在2-位具有氨基取代基的1H-咪唑环体系(例如咪唑并吡啶,咪唑并喹啉,咪唑并萘啶,6,7,8,9-四氢咪唑并喹啉和咪唑并萘啶),含有这些化合物的药物组合物,制备所述化合物的方法,中间体 ,以及这些化合物作为免疫调节剂的用途,用于调节动物细胞因子生物合成和治疗包括病毒和肿瘤疾病在内的疾病的方法。

Patent Agency Ranking