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11.发明公开MULTIPLE GENE EXPRESSION INCLUDING SORF CONSTRUCTS AND METHODS WITH POLYPROTEINS, PRO-PROTEINS, AND PROTEOLYSIS 审中-公开表达的几个基因，OF SORF构建体及与多聚PROPROTEINEN和蛋白水解方法，包括
公开(公告)号：EP1910550A4
公开(公告)日：2009-11-04
申请号：EP06788320
申请日：2006-07-21
Applicant: ABBOTT LAB
Inventor： CARSON GERALD R , GION WENDY , SALFELD JOCHEN G , GU JIJIE , REGIER DEAN A , KUNES YUNE
IPC: C12N15/63 , C12P21/06 , C07H21/02 , C07H21/04 , C07K16/18 , C12N1/18 , C12N5/07 , C12N5/071 , C12N15/00 , C12P21/08
CPC classification number: C12N15/67 , C07K16/00 , C07K2319/50 , C07K2319/92 , C12N15/1055 , C12P21/02 , C12P21/06
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公开(公告)号：EP2056869A4
公开(公告)日：2009-10-21
申请号：EP07811045
申请日：2007-08-03
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
CPC classification number: C07K16/468 , A61K39/3955 , A61K45/06 , A61K47/42 , A61K47/48384 , A61K47/6803 , A61K51/1093 , A61K2039/505 , C07K16/22 , C07K16/24 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/2809 , C07K16/2887 , C07K16/2896 , C07K16/40 , C07K16/46 , C07K16/467 , C07K2317/24 , C07K2317/31 , C07K2317/51 , C07K2317/522 , C07K2317/56 , C07K2317/64 , C07K2317/76
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
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公开(公告)号：EP2493924A4
公开(公告)日：2013-05-29
申请号：EP10830460
申请日：2010-10-28
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , SALFELD JOCHEN G , MCPHERSON MICHAEL J , HARRIS MARIA C , LIU JUNJIAN , ISAKSON PETER C , GU JIJIE
IPC: C07K16/46 , A61K39/395 , C07K16/22 , C07K16/28
CPC classification number: C07K16/241 , C07K16/22 , C07K16/2803 , C07K16/2875 , C07K16/44 , C07K16/468 , C07K2317/31 , C07K2317/73
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14.发明公开
公开(公告)号：EP1928506A4
公开(公告)日：2009-10-21
申请号：EP06813554
申请日：2006-08-18
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
CPC classification number: C07K16/241 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/244 , C07K16/28 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/64 , C07K2317/94
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及其用于预防和/或治疗急性和慢性炎症和其它疾病的用途。
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公开(公告)号：SG2014010029A
公开(公告)日：2014-08-28
申请号：SG2014010029
申请日：2006-08-18
Applicant: ABBOTT LAB , ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
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Patent Agency Ranking
公开(公告)号：CA2618482C
公开(公告)日：2014-10-07
申请号：CA2618482
申请日：2006-08-18
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
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公开(公告)号：NZ597168A
公开(公告)日：2013-07-26
申请号：NZ59716806
申请日：2006-08-18
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
IPC: A61K38/00 , A61K31/192 , A61K31/343 , A61K31/365 , A61K31/4152 , A61K31/445 , A61K31/496 , A61K31/551 , A61K31/60 , A61K39/395 , A61K49/00 , A61K49/14 , A61K49/16
Abstract: 597168 DUAL VARIABLE DOMAIN IMMUNOGLOBIN AND USES THEREOF Provided is a binding protein comprising first and second polypeptide chains, wherein said first polypeptide chain comprises VD1-(X1)n-VD2-C-(X2)n, wherein VD1 is a first immunoglobulin heavy chain variable domain, VD2 is a second immunoglobulin heavy chain variable domain, C is an immunoglobulin constant domain, X1 is a linker with the proviso that it is not an immunoglobulin constant domain, and X2 is an Fc region; and said second polypeptide chain comprises VD1-(X1)n-VD2-C-(X2)n, wherein VD1 is a first immunoglobulin light chain variable domain, VD2 is a second immunoglobulin light chain variable domain, C is an immunoglobulin constant domain, X1 is a linker with the proviso that it is not an immunoglobulin constant domain, and X2 is an Fc region; wherein n is 0 or 1; and wherein the first and second polypeptide chains form two functional antigen binding sites.
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公开(公告)号：AU2012205249A1
公开(公告)日：2012-08-09
申请号：AU2012205249
申请日：2012-07-19
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Abstract: DUAL VARIABLE DOMAIN IMMUNOGLOBIN AND USES THEREOF The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
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公开(公告)号：CA2778140A1
公开(公告)日：2011-05-19
申请号：CA2778140
申请日：2010-10-28
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , SALFELD JOCHEN G , MCPHERSON MICHAEL J , HARRIS MARIA C , LIU JUNJIAN , ISAKSON PETER C , GU JIJIE
IPC: A61K39/395 , A61K47/48 , A61K51/10
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：BRPI0615026A2
公开(公告)日：2009-06-16
申请号：BRPI0615026
申请日：2006-08-18
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
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