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    11.
    发明专利
    未知

    公开(公告)号：DE50007725D1

    公开(公告)日：2004-10-21

    申请号：DE50007725

    申请日：2000-03-18

    Applicant: BASF AG

    Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

    IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42

    Abstract: Amino-substituted hydroxybenzophenones (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. Amino-substituted hydroxybenzophenones of formula (I) are used as photostable UV filters in cosmetic and pharmaceutical compositions for protecting human skin or hair against solar radiation, optionally in combination with other UV absorbers. [Image] R1>, R2>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl or 3-10C cycloalkenyl, or NR1>R2> is a 5- or 6-membered ring; R3>, R4>1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl, nitrile, carboxylate, sulfonate or ammonium; X : H, COOR5> or CONR6>R7>; R5>-R7>H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, (YO)oZ or aryl; Y : (CH2)x or CH(Me)CH2; x : 2-4; Z : Et, n-Pr, n-Bu or i-Pr; m : 0-3; n : 0-4; o : 1-20. Independent claims are also included for: (1) use of (I) as UV stabilizers in cosmetic and pharmaceutical compositions; (2) cosmetic and pharmaceutical compositions for protecting human skin or hair against UV light of wavelength 280-400 nm, comprising compounds (I) in a carrier, optionally in combination with other UV absorbers.

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