公开(公告)号：JP2000044451A

公开(公告)日：2000-02-15

申请号：JP15677699

申请日：1999-06-03

Applicant: BASF AG

Inventor： SCHUMACHER PETER ,  SCHNEIDER NORBERT ,  WESTENFELDER HORST ,  HAREMZA SYLKE DR ,  HABECK THORSTEN ,  MEYER FRANK

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/23 ,  A61K8/25 ,  A61K8/29 ,  A61K8/31 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/73 ,  A61K8/86 ,  A61K8/89 ,  A61K8/97 ,  A61K8/98 ,  A61K31/255 ,  A61K31/34 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C09B67/20 ,  C09C3/08 ,  C09K3/00 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To protect human epidermis or human hair against sunrays by using a specific cholesteric liquid crystal composition as a filter in a UV-A and a UV-B regions of a cosmetic and a medicine. SOLUTION: A cholesteric liquid crystal composition is obtained by including (A) a polymerizable chiral liquid crystal monomer capable of providing a cholesteric liquid crystal phase having

公开(公告)号：JP2000319628A

公开(公告)日：2000-11-21

申请号：JP2000115373

申请日：2000-04-17

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  HAREMZA SYLKE ,  BACH THORSTEN ,  SPIEGEL ANJA

IPC: C07D295/14 ,  A61K8/00 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K31/136 ,  A61K31/196 ,  A61K31/24 ,  A61K31/40 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C225/00 ,  C07C225/22 ,  C07C229/52 ,  C07D295/10 ,  C07D295/112 ,  C09K3/00 ,  A61K7/42 ,  A61K7/44

Abstract: PROBLEM TO BE SOLVED: To obtain a light protectant having a high absorbance in the UV-A region, being light-stable, having a sharp bend structure, being soluble in an oil or water dependent on the substituent, and intended for cosmetics and medicines by using an amino-substituted hydroxybenzophenone. SOLUTION: The amino-substituted hydroxybenzophenone represented by the formula is used alone or in combination with other compounds having absorptions in the UV-A region and intended for cosmetics and medicinal preparations as a light-stable UV filter for use in cosmetics or medicinal preparations for protecting the human skin or hair from sunlight. In the formula, R1 and R2 are each H, a 1-20C alkyl, a 2-10C alkenyl, a 3-10C cycloalkyl, or the like; R3 and R4 are each a 1-20C alkyl, a 3-10C cycloatkyl, a 1-12C alkoxyl, a 1-20C alkoxycarbonyl, or the like; X is H, COOR5, or CONR6R7; R5 to R7 are each H, a 1-20C alkyl, or the like; m is 0-3; and n is 0-4.

公开(公告)号：JPH11269167A

公开(公告)日：1999-10-05

申请号：JP3751299

申请日：1999-02-16

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  KRAUSE ALFRED

IPC: C07D319/06 ,  A61K8/00 ,  A61K8/49 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/04 ,  C07D319/08 ,  C07D409/06 ,  A61K7/06 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To use a malonic ester compound having a slight characteristic color and soluble in oil and water, useful for a cosmetic for protecting human skin and hair from sunlight and an UV-filter having light stability in preparations of medicines. SOLUTION: A malonic ester derivative of formula I [R and R are each H or a 1-20C alkyl or the like; R is a group of formula II or formula III (R to R are each H, OH, a 1-20C alkyl or the like; X is O, S or NH; (n) is 0 or 1); R is H, a 1-20C alkyl or a group of formula IV; R is H, a 1-20C alkyl, OH or the like] is used alone or together with a compound having absorption in an UV range known by itself as a preparation for a cosmetic or a medicine in a preparation for a cosmetic or a medicine for protecting human skin or hair from sunlight, preferably as a UV stabilizer or a UV filter having light stability (preferably a UV-A filter having light stability). The compound of formula I in an amount of preferably 1-7 wt.% based on the total amount of a preparation is contained as a photoprotective agent.

公开(公告)号：JP2002155189A

公开(公告)日：2002-05-28

申请号：JP2001289838

申请日：2001-09-21

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  MATHAUER KLEMENS ,  WUENSCH THOMAS ,  WESTENFELDER HORST ,  ICHIHARA HIDEYUKI ,  IKEDA HISAHIRO ,  DAUSCH WILMA M

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/81 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q5/10 ,  A61Q17/04 ,  C08F2/22 ,  C08F2/24 ,  C08F2/44 ,  C08K5/00 ,  C08L57/00 ,  A61K7/00 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To provide a colorant-containing aqueous polymer dispersion containing no anionic emulsifying agent, its manufacturing method, and a cosmetic composition using the same. SOLUTION: The colorant-containing aqueous polymer dispersion comprises (a) (i) a polymer matrix to be prepared from an ethylenically unsaturated monomer M and (ii) colorant-containing polymer particles which are uniformly dispersed in the above polymer matrix and contain at least one organic colorant C to be selected from a dye, an UV absorber, and a fluorescent brightener and, simultaneously, have an average particle diameter d50 of

公开(公告)号：JPH11116455A

公开(公告)日：1999-04-27

申请号：JP22888398

申请日：1998-08-13

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  HAREMZA SYLKE ,  SCHEHLMANN VOLKER DR ,  WESTENFELDER HORST ,  WUENSCH THOMAS DR ,  DROEGEMUELLER MICHAEL DR ,  BOMM VOLKER

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K31/12 ,  A61K31/122 ,  A61K31/216 ,  A61K31/277 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C69/618 ,  C07C69/76 ,  C07C233/00 ,  C07C233/11 ,  C07C235/34 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To prepare a cosmetic or the like, having a high absorbance in the UV-A area, showing a high photoresistibility and high stability, capable of manifesting pleasant touch feeling by using a specific 4,4-diarylbutadiene with a well-known compound. SOLUTION: This compound is 4,4-diarylbutadiene of formula I [R and R are each H, a 1-20C alkyl, a 2-10C alkenyl, an aryl or the like; R is H, COOR (R is H, a 1-20C alkyl or the like), a 1-20C alkyl, CN or the like; R is COOR (R is same as R ), CN, a 1-20C alkyl or the like; (n) is 1-3], e.g. the compound of formula II. The compound of formula I is obtained by condensing a compound of formula III with a compound of formula IV. The compound of formula I itself is well-known, and is used together with a compound used as a sun-screening agent for preparations for cosmetics and pharmaceutical preparations. The compound of formula I is preferably used in the proportion of 0.1-10 wt.% based on the whole quantity of the preparation.

公开(公告)号：JP2002047283A

公开(公告)日：2002-02-12

申请号：JP2001201424

申请日：2001-07-02

Applicant: BASF AG

Inventor： HAREMZA SYLKE ,  PRECHTL FRANK ,  HABECK THORSTEN

IPC: A61K8/00 ,  A61K8/49 ,  A61K31/352 ,  A61P17/16 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  C07D311/22 ,  C07D311/30 ,  C07D405/04 ,  C07D405/06 ,  C07D407/06 ,  A61K7/00 ,  A61K7/48

Abstract: PROBLEM TO BE SOLVED: To obtain a new flavonoid improved in an UV absorption action and an antioxidative action. SOLUTION: This flavonoid is represented by general formula I [R is a group of formula Ia or a group of formula Ib (R1 is hydrogen, a 1-4C alkyl, hydroxyl, a 1-4C alkoxy, a phenyloxy or a benzyloxy; R2 is hydrogen or a 1-4C alkyl; R3 is hydrogen, a 1-4C alkyl, a 1-4C alkoxy or cyano; R4 is hydrogen, a 1-4C alkyl or phenyl; (n) is 0 or 1; and Het is pyridyl, furyl or methylpyrrolyl group, with the proviso that when R is Ia and (n) is 0, at most two of R1 to R3 are each hydrogen at the same time).

公开(公告)号：JP2000169354A

公开(公告)日：2000-06-20

申请号：JP34061699

申请日：1999-11-30

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  PRECHTL FRANK ,  WUENSCH THOMAS DR ,  WESTENFELDER HORST

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/40 ,  A61K8/49 ,  A61K31/275 ,  A61K31/277 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  A61Q19/00 ,  C07C255/37 ,  A61K7/42 ,  A61K7/00 ,  A61K7/48

Abstract: PROBLEM TO BE SOLVED: To obtain a light stabilizer which is, photostable, shows a bright band structure, and soluble in oil and water by use of a specific α-alkyl styrol derivative dimer, either individually or in combination with another compound, as a photostable UV filter for cosmetic preparations or the like for protecting human skin or the like from sun beams. SOLUTION: This α-alkyl styrol derivative dimer represented by formula I [R1 and R2 are each H, OH or the like; R3 and R4 are each COOR6, COR6 or the like; R5 is a 1-12C alkyl; R6 is H, a (substituted) alkyl or the like; A is O, S or the like; and B is a 1-12C alkylene, a 4-12C cycloalkylene or the like], e.g. a compound represented by formula II, is used as a photostable UV filter for cosmetic preparations or the like for protecting human skin or hair from sun beams, either individually or in combination with a known compound which absorbs light in the UV range for cosmetic or pharmaceutical preparations, e.g. 4-aminobenzoic acid.

公开(公告)号：JPH1067635A

公开(公告)日：1998-03-10

申请号：JP22346197

申请日：1997-08-20

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  AUMUELLER ALEXANDER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/40 ,  A61K8/49 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/40 ,  C07D307/52 ,  C07D317/54 ,  C07D333/24 ,  A61K7/42 ,  A61K7/00

Abstract: PROBLEM TO BE SOLVED: To obtain a cosmetic preparation for protecting human skins from solar light by using a partially specific new compound as a UV light filter singly or together with a known light-absorbing compound in a UV light region. SOLUTION: This α-acyl, β-allylacylnitrile of formula I (R to R are each H, a 18C aliphatic or alicyclic group, or two of R to R together form a five or six-membered ring; R , R are each an aromatic or heteroaromatic group having 5-12 atoms in the ring; R may be H) is used as a UV-A filter. A compound of formula II [R to R are each a low mol.wt. alkyl; R is 2-thienyl, 4-(3,5-di-t-butyl)-1-hydroxy, an alkoxyphenyl] among the compounds of formula I is new. The contact of the compound of formula I in a cosmetic preparation is approximately 10-90 pts.wt. based on the whole amount of the UV-B and UV-A absorbing substances. The UV-B filter substance is e.g. 4-aminobenzoic acid, etc.

公开(公告)号：WO0172935A3

公开(公告)日：2002-02-14

申请号：PCT/EP0103470

申请日：2001-03-27

Applicant: BASF AG ,  HEIDENFELDER THOMAS ,  WAGENBLAST GERHARD ,  DETERING JUERGEN ,  HABECK THORSTEN

Inventor： HEIDENFELDER THOMAS ,  WAGENBLAST GERHARD ,  DETERING JUERGEN ,  HABECK THORSTEN

IPC: C11D3/26 ,  A61K8/40 ,  A61Q17/04 ,  C09K3/00 ,  C11D3/42 ,  D06L3/12 ,  D06M13/07 ,  D06M13/127 ,  D06M13/152 ,  D06M13/224 ,  D06M13/352 ,  D06M13/358 ,  D06M13/372 ,  D06P1/642 ,  D06P1/651 ,  D06P5/04 ,  D06P5/08 ,  A61K7/42 ,  D06M13/402 ,  D06M15/59

CPC classification number: D06M13/2246 ,  A61K8/40 ,  A61Q17/04 ,  C11D3/42 ,  D06L4/614 ,  D06L4/65 ,  D06L4/657 ,  D06M13/07 ,  D06M13/127 ,  D06M13/152 ,  D06M13/224 ,  D06M13/352 ,  D06M13/358 ,  D06M13/372 ,  D06P1/6426 ,  D06P1/65112 ,  D06P1/65125 ,  D06P1/6515 ,  D06P5/04 ,  D06P5/08

Abstract: The invention relates to a mixture, comprising (A) 10 to 90 wt. % of at least one C6 to C18 alkyl ester, or C5 to C8 cycloalkyl ester of 2-cyano-3,3-diphenylacrylic acid and (B) 90 to 10 wt. % of at least one further compound, with at least one UV absorption maximum in the range 280 to 450 nm and structurally different from compound (A). Said mixture is suitable for the protection of human skin from damaging UV radiation and for the protection of coloured textile materials from colour fading.

Abstract translation: 本Orfindung bettuft的混合物：（A）10〜90重量％的至少一种C6-C18烷基酯或2-氰基-3,3-二苯基丙烯酸C5-C8环烷基酯和（B）90〜10％的 是重量具有至少一个UV吸收最大值的范围为280至450nm以及从化合物（a）结构上不同的至少一个另外的化合物的％。 此混合物适合作为纤维亲和力紫外线吸收剂，以防止有害的紫外线辐射对人体皮肤和保护染色纺织材料对抗衰落。

公开(公告)号：AU757965B2

公开(公告)日：2003-03-13

申请号：AU3680199

申请日：1999-06-25

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  WESTENFELDER HORST ,  WUNSCH THOMAS

IPC: A61K47/06 ,  A61K8/00 ,  A61K8/30 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61K31/00 ,  A61K31/075 ,  A61K31/16 ,  A61K31/165 ,  A61K31/19 ,  A61K31/215 ,  A61K31/275 ,  A61P17/00 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/04 ,  C07C59/40 ,  C07C69/612 ,  C07C69/618 ,  C07C69/73 ,  C07C69/734 ,  C07C69/738 ,  C07C233/40 ,  C07C309/12 ,  C07C309/58 ,  C07C309/59 ,  C09K3/00 ,  A61K7/06 ,  A61K7/42 ,  C07C233/22