公开(公告)号：JP2003183145A

公开(公告)日：2003-07-03

申请号：JP2002327175

申请日：2002-11-11

Applicant: BASF AG

Inventor： PARKER ROBERT ,  HEIDENFELDER THOMAS ,  WAGENBLAST GERHARD

IPC: A61K8/00 ,  A61K8/29 ,  A61K8/31 ,  A61K8/33 ,  A61K8/35 ,  A61K8/36 ,  A61K8/368 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/49 ,  A61K8/58 ,  A61K8/63 ,  A61K8/81 ,  A61K8/85 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/00 ,  A61Q17/04 ,  A61K7/40 ,  A61K7/025 ,  A61K7/06 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To provide a cosmetic or dermatological light protection agent preparation which may be easily prepared and provides an effective protection against UV or heat irradiation. SOLUTION: This cosmetic or dermatological preparation for skin or hair comprises at least one cholesteric liquid-crystalline component which reflects the infrared wavelength range of 750-2,500 nm, at least one component which protects against radiation in the ultraviolet ray range of 280-450 nm and a cosmetically or dermatologically acceptable carrier. The preparation is used for reducing the warming of skin or hair and for protection against sun beam. COPYRIGHT: (C)2003,JPO

公开(公告)号：JP2001261540A

公开(公告)日：2001-09-26

申请号：JP2001070070

申请日：2001-03-13

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  HABECK THORSTEN DR ,  WUENSCH THOMAS DR

IPC: A61K47/02 ,  A61K8/00 ,  A61K8/29 ,  A61K8/33 ,  A61K8/35 ,  A61K8/37 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K8/58 ,  A61K8/893 ,  A61K8/896 ,  A61K8/898 ,  A61K47/08 ,  A61K47/14 ,  A61K47/18 ,  A61K47/22 ,  A61K47/24 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q5/00 ,  A61Q17/04 ,  C08L83/06 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To provide a light protective agent having high absorbance in UV-A region, stable to light, exhibiting slight intrinsic color, i.e., a sharp band structure, getting soluble to water or oil through substituent manipulation, and intended for cosmetics and pharmaceutical preparations. SOLUTION: The subject light protective agent combination comprises (A) compound(s) with absorbance mainly in UV-A region and (B) compound(s) with absorbance both in UV-A and UV-B regions; wherein the component A essentially comprises A(a) an effective amount of a hydroxybenzophenone of the general formula I and, optionally in addition, A(b) an effective amount of a 4,4-diarylbutadiene of the general formula II, and the component B comprises an effective amount of at least one compound selected from the group consisting of compounds B(a), B(b), B(c), B(d), B(e), B(f), B(g) and B(h) of respective formulas III, IV, V, VI, VII, VIII, IX and Xa and/or Xb. The light protective agent combination can be used as a light-stable filter in cosmetic preparations and pharmaceutical preparations for protecting human skin or human hair from sunlight.

公开(公告)号：JP2003146865A

公开(公告)日：2003-05-21

申请号：JP2002260758

申请日：2002-09-06

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WUENSCH THOMAS ,  ANDRE VALERIE

IPC: A61K8/00 ,  A61K8/04 ,  A61K8/06 ,  A61K8/25 ,  A61K8/30 ,  A61K8/41 ,  A61K8/44 ,  A61K8/72 ,  A61K8/73 ,  A61K8/81 ,  A61K8/87 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61K7/48 ,  A61K7/00

Abstract: PROBLEM TO BE SOLVED: To provide a cosmetic or a dermatological preparation containing little or no emulsifier. SOLUTION: The cosmetic or dermatological preparation is an O/W-type fine dispersion containing (a) an oil, (b) water, (c) one or more kinds of stabilizers (methyl cellulose, xanthan, carrageenan, a copolymer of an acrylic ester and acrylic acid, polyurethane, etc.), (d) one or more kinds of emulsifiers of an amount of

公开(公告)号：JP2003095851A

公开(公告)日：2003-04-03

申请号：JP2002260738

申请日：2002-09-06

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WUENSCH THOMAS ,  ANDRE VALERIE

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/02 ,  A61K8/11 ,  A61K8/33 ,  A61K8/34 ,  A61K8/36 ,  A61K8/368 ,  A61K8/37 ,  A61K8/41 ,  A61K8/44 ,  A61K8/58 ,  A61K8/89 ,  A61K8/891 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  C08L83/04 ,  A61K7/00 ,  A61K7/027

Abstract: PROBLEM TO BE SOLVED: To provide a cosmetic preparation and a dermatological preparation in a stick form comprising an amino-substituted hydroxybenzophenone. SOLUTION: The cosmetic stick comprises (a) a fatty phase comprising at least one oil component and/or at least one wax component and (b) the amino-substituted hydroxybenzophenone represented by the following formula I.

公开(公告)号：JP2002308751A

公开(公告)日：2002-10-23

申请号：JP2002069215

申请日：2002-03-13

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  TIEFENSEE KRISTIN ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/02 ,  A61K8/06 ,  A61K8/33 ,  A61K8/37 ,  A61K8/41 ,  A61K8/49 ,  A61K8/58 ,  A61K8/89 ,  A61K8/891 ,  A61K31/12 ,  A61K31/216 ,  A61K31/225 ,  A61K31/24 ,  A61K31/4184 ,  A61K31/4192 ,  A61K31/53 ,  A61K31/695 ,  A61K31/80 ,  A61P17/00 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C08L83/08 ,  A61K7/42 ,  A61K7/00 ,  A61K7/025

Abstract: PROBLEM TO BE SOLVED: To provide a sunscreening agent for cosmetics and pharmaceuticals, having absorption of high absorptivity in UV-A area, being photostable, having slight characteristic color, namely having sharp band structure and being soluble in oil or water, depending on the substituent group. SOLUTION: This invention relates to use of a combination of sunscreening agents comprising suncreening agent of 2-(4-alkoxyanilino-methylene)malonic acid dialkyl ester and at least one kind of specific suncreening agent having absorption in UV-A area, UV-B area or these both areas as a photostable UV filter in cosmetic and pharmaceutical preparation for protecting human epidermis or human hair from ultraviolet light, particularly ultraviolet light having 320-400 nm area.

公开(公告)号：JP2002212043A

公开(公告)日：2002-07-31

申请号：JP2001384166

申请日：2001-12-18

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  TIEFENSEE KRISTIN ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/29 ,  A61K8/33 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/44 ,  A61K8/49 ,  A61K8/58 ,  A61K8/89 ,  A61K8/892 ,  A61K8/895 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C08L83/07 ,  A61K7/42 ,  A61K7/06

Abstract: PROBLEM TO BE SOLVED: To obtain a combined sun screen useful as a photostable UV filter in a cosmetic and a medicine, having an absorption in an UV-A region. SOLUTION: This use of the combined sun screen as a photostable UV filter in a cosmetic and a medicine for protecting the human skin or hair from sunbeam is characterized in that the combined sun screen may be used with another compound as an arbitrary component well-known by itself for a cosmetic and a medicine, having an absorbance in the UV region and comprises (A) a compound essentially having an absorbance in the UV-A region and (B) an other compound having an absorbance in the UV-A region or the UV-B region or both the regions in which the component (A) having an absorbance in the UV-A region is composed of an effective amount of a compound represented by formula I and the component (B) comprises an effective amount of one or more kinds of compounds selected from the group consisting of compounds (Ba) to (Bp).

公开(公告)号：JP2003113020A

公开(公告)日：2003-04-18

申请号：JP2002259699

申请日：2002-09-05

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WUENSCH THOMAS ,  ANDRE VALERIE

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/06 ,  A61K8/33 ,  A61K8/34 ,  A61K8/37 ,  A61K8/41 ,  A61K8/44 ,  A61K8/58 ,  A61K8/72 ,  A61K8/89 ,  A61K8/891 ,  A61K8/894 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61K7/00 ,  A61K7/40

Abstract: PROBLEM TO BE SOLVED: To provide a cosmetic preparation and a dermatological composition each in the form of a water/oil emulsion containing an amino-substituted hydroxybenzophenone. SOLUTION: The cosmetic composition or the dermatological composition in the form of a water/oil emulsion contains the amino-substituted hydroxybenzophenone of formula I.

公开(公告)号：JP2003095850A

公开(公告)日：2003-04-03

申请号：JP2002260069

申请日：2002-09-05

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  WUENSCH THOMAS ,  ANDRE VALERIE

IPC: A61K8/30 ,  A61K8/06 ,  A61K8/33 ,  A61K8/34 ,  A61K8/37 ,  A61K8/41 ,  A61K8/44 ,  A61K8/58 ,  A61K8/891 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  C08L83/04 ,  A61K7/00

Abstract: PROBLEM TO BE SOLVED: To provide a cosmetic preparation and a dermatological preparation in the form of an O/W emulsion comprising an amino-substituted hydroxybenzophenone. SOLUTION: This cosmetic or dermatological preparation in the form of the O/W emulsion comprises the amino-substituted hydroxybenzophenone represented by the following formula I.

公开(公告)号：JP2003012655A

公开(公告)日：2003-01-15

申请号：JP2002133897

申请日：2002-05-09

Applicant: Basf Ag ,  ビーエーエスエフ アクチェンゲゼルシャフト

Inventor： HEIDENFELDER THOMAS ,  TIEFENSEE KRISTIN ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/49 ,  A61K31/53 ,  A61P17/16 ,  A61Q17/04 ,  A61Q19/00 ,  C07D251/70 ,  A61K7/00 ,  A61K7/42 ,  A61K7/48

CPC classification number: A61Q17/04 ,  A61K8/4966 ,  C07D251/70

Abstract: PROBLEM TO BE SOLVED: To provide a new UV filter having a combination of properties including both high UV absorptivity and UV stability in the UV-A and/or UV-B region(s).
SOLUTION: A use of an enaminotriazine of the formula I [where, Y groups are each H or a (substituted) ≤18C aliphatic, alicyclic, araliphatic, or aromatic group; X groups are the same as or different from each other, at least one of them being an ethenyl group of the formula II; the X groups may be the same as the Y groups; the R groups in the formula II are each cyano, (esterified) carboxy, or the like; R' is H or a (substituted) ≤18C aliphatic, alicyclic, or aromatic group] as a UV filter in a cosmetic or pharmaceutical preparation for protecting human skin or hair from sunlight is provided.
COPYRIGHT: (C)2003,JPO

Abstract translation: 要解决的问题：提供一种具有UV-A和/或UV-B区域中的高紫外线吸收率和UV稳定性两者的组合的新的UV滤光器。 解决方案：使用式I的氨基三嗪[其中，Y基团各自为H或（取代的）= = 18C脂族，脂环族，芳族脂族或芳族基团; X基彼此相同或不同，其中至少一个为式II的乙烯基; X组可能与Y组相同; 式II中的R基团各自为氰基，（酯化）羧基等; 提供了用于保护人类皮肤或头发免受阳光照射的化妆品或药物制剂中的UV或者取代的（取代的）= 18C脂肪族，脂环族或芳族基团。

公开(公告)号：JP2001348318A

公开(公告)日：2001-12-18

申请号：JP2001074833

申请日：2001-03-15

Applicant: BASF AG

Inventor： HEIDENFELDER THOMAS ,  HABECK THORSTEN DR ,  WUENSCH THOMAS DR

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/49 ,  A61K8/89 ,  A61K8/893 ,  A61K8/896 ,  A61K8/898 ,  A61K31/121 ,  A61K31/216 ,  A61K31/4184 ,  A61K31/4192 ,  A61K31/53 ,  A61K31/695 ,  A61K31/77 ,  A61K33/24 ,  A61K33/30 ,  A61P17/16 ,  A61Q1/04 ,  A61Q17/04 ,  C08L83/07 ,  A61K7/42 ,  A61K7/025

Abstract: PROBLEM TO BE SOLVED: To provide a sunscreen for a cosmetic preparation or a medicine exhibiting an absorbance in UV-A region in high absorbance, light stable, having a clear inherent color, i.e., a sharp absorption band and soluble in oil or water depending on its substituting group. SOLUTION: This cosmetic or medical preparation comprises A) a compound substantially exhibiting absorbance in UV-A region, and B) a compound exhibiting absorbance in UV-A region, UV-B region and a region more than both as the UV filter. The compound A) is a derivative of 4,4'-diaryl butadiene of general formula (1), and a triazine derivative, a triazole derivative, a benzimidazole derivative, a benzotriazole derivative, a tetrahydroxybenzophenone derivative or the like are exhibited as the B) compound. [R1 and R2 are each H, a 1-20C alkyl group, a 3-10C cycloalkyl group or a 3-10C cycloalkenyl group].