公开(公告)号：AT271866T

公开(公告)日：2004-08-15

申请号：AT01963002

申请日：2001-09-11

Applicant: BASF AG

Inventor： HASSELWANDER OLIVER ,  KRAEMER KLAUS ,  BALDENIUS KAI-UWE ,  KLATT MARTIN JOCHEN ,  SCHWEIKERT LONI

IPC: A61K31/381 ,  A23L1/30 ,  A61K31/00 ,  A61K31/202 ,  A61K31/385 ,  A61P3/10 ,  A61P9/10 ,  A61P13/12 ,  A61P25/02 ,  A61P27/02 ,  A61K31/20

Abstract: The present invention relates to the use of lipoic acid, a physiologically acceptable derivative or salt thereof and one compound of the formula I H3C-(CH2)n1-(CH=CH)n3-(CH2)n2-COOH I in which n1, n2 have, independently of one another, the value of an integer from 3 to 9, n3 has the value of an integer from 2 to 6, and the number of carbon atoms is 18, 20 or 22, a physiologically acceptable derivative or salt thereof, for nutritional supplementation, in functional foods and for therapeutic purposes in the treatment of diabetic disorders. Compositions having a corresponding active ingredient combination, and compositions in the form of commercial packs with corresponding combination products or single-drug products for combined use are also described.

公开(公告)号：DK1301501T3

公开(公告)日：2004-07-19

申请号：DK01969391

申请日：2001-07-13

Applicant: BASF AG

Inventor： BALDENIUS KAI-UWE ,  SCHROEDER HARTWIG ,  KRAEMER KLAUS ,  SCHEIN KARIN ,  STUERMER RAINER

IPC: A23L33/105 ,  A61K31/34 ,  A61K31/343 ,  A61P3/00 ,  A61P3/06 ,  A61P3/10 ,  A61P7/02 ,  A61P9/00 ,  A61P9/10 ,  C07C46/06 ,  C07C50/28 ,  C07D307/04 ,  C07D307/94

Abstract: A description is given of the use of at least one compound of the formula I where R 1 , R 2 , R 3 and R 4 independently of one another are H or C 1 -C 6 -alkyl; and the use of a compound of the formula I for medical use.

公开(公告)号：ZA200209941B

公开(公告)日：2004-03-09

申请号：ZA200209941

申请日：2002-12-09

Applicant: BASF AG

Inventor： HASSELWANDER OLIVER ,  HAEHNLEIN WOLFGANG ,  KRAEMER KLAUS ,  SCHWEIKERT LONI

IPC: A23L1/30 ,  A23C9/158 ,  A23K1/16 ,  A23L1/305 ,  A23L2/52 ,  A23L33/00 ,  A23L33/15 ,  A61K31/4415 ,  A61K31/519 ,  A61K31/7076 ,  A61K31/714 ,  A61P9/00 ,  A61P25/00 ,  C07D475/04 ,  A23L

Abstract: Compositions are proposed which comprise folic acid in combination with 5-methyltetrahydrofolic acid, and also compositions which comprise folic acid, 5-methyltetrahydrofolic acid and/or 5-methyltetrahydrofolylpolyglutamate and also comprise a dietary component and/or a nutrient preparation, and their use is also proposed.

公开(公告)号：ZA200200334B

公开(公告)日：2003-06-25

申请号：ZA200200334

申请日：2002-01-15

Applicant: BASF AG

Inventor： RADEMACHER WILHELM ,  KRAEMER KLAUS ,  SCHWEDEN JUERGEN

IPC: A01G7/00 ,  A01N37/42 ,  A61K8/96 ,  A61K8/97 ,  A61K36/00 ,  A61P3/06 ,  A61P3/10 ,  A61P9/00 ,  A61P35/00 ,  A61P39/06 ,  A61P43/00 ,  A01N

Abstract: The invention relates to a method of increasing the flavonoid content of plants by treating the plants with the growth-regulating acylcyclohexadiones according to formula (I).

公开(公告)号：DE10109303A1

公开(公告)日：2002-11-28

申请号：DE10109303

申请日：2001-02-26

Applicant: BASF AG

Inventor： KRAEMER KLAUS ,  KLATT MARTIN JOCHEN

IPC: A61K33/00 ,  A61K31/381

Abstract: A composition (I) comprising at least one mineral salt and (R)- alpha -lipoic acid or (S)- alpha -lipoic acid is claimed. Independent claims are included for (i) a metal - alpha -lipoate, metal- alpha -dihydrolipoate or metal- alpha -lipoic acid complex of formula (1) excluding Mn(Lip )ClO4, Cu(Lip )ClO4, Cd(Lip )ClO4, Pb(Lip )ClO4, Hg(liprac)(OH)2, Hg(DHLrac -), Ni(DHLrac -), Fe2(DHLrac -)3, Zn(Liprac )2(H2O)2 and Cd(Liprac )2(H2O)2. (M)w(Lp)x(A)y(H2O)z (1) M = 1-3 valent, physiologically compatible metal cation; Lp = racemic alpha -lipoic acid or alpha -dihydrolipoic acid, (R)- or (S)- alpha -lipoic or (R)- or (S)- alpha -dihydrolipoic acid, racemic alpha -lipoate or dihydro- alpha -lipoate or (R)- or (S)- alpha -lipoate or (R)- or (S)-dihydro- alpha -lipoate; (A) = physiologically compatible mono- or divalent anion; w = 1 or 2; x = 1-4; y = 0-3; z = 0-6; Lip=monovalent negative racemic, (R)- or (S)- alpha -lipoate; Liprac = monovalent negative racemic alpha -lipoate; Liprac = racemic alpha -lipoic acid; DHLrac = divalent, negative, racemic alpha -dihydrolipoate (ii) compositions comprising a metal - alpha -lipoate, metal- alpha -dihydrolipoate or metal- alpha -lipoic acid complex of formula (1) (iii) the use of alpha -lipoic acid or alpha -dihydrolipoic acid for improving the bioavailability of mineral salts.

公开(公告)号：DE10034233A1

公开(公告)日：2002-01-24

申请号：DE10034233

申请日：2000-07-14

Applicant: BASF AG

Inventor： BALDENIUS KAI-UWE ,  SCHROEDER HARTWIG ,  KRAEMER KLAUS ,  SCHEIN KARIN ,  STUERMER RAINER

IPC: A23L33/105 ,  A61K31/34 ,  A61K31/343 ,  A61P3/00 ,  A61P3/06 ,  A61P3/10 ,  A61P7/02 ,  A61P9/00 ,  A61P9/10 ,  C07C46/06 ,  C07C50/28 ,  C07D307/04 ,  C07D307/94 ,  C07D311/72 ,  A23L1/29

Abstract: The invention relates to the use of at least one component of formula (I) wherein R , R , R and R independently represent H or C1-C6 alkyl. The invention also relates to the use of a compound of formula (I) for medical purposes.

公开(公告)号：DE19835850A1

公开(公告)日：2000-02-10

申请号：DE19835850

申请日：1998-08-07

Applicant: BASF AG

Inventor： KRAEMER KLAUS ,  BALDENIUS KAI-UWE ,  HOPPE PETER PAUL

IPC: A23K20/105 ,  A23K20/174 ,  A23K50/75 ,  A61K31/045 ,  A61K31/12 ,  A61K31/22 ,  A61K31/353 ,  A23K1/16 ,  A23K1/18

公开(公告)号：ES2225593T3

公开(公告)日：2005-03-16

申请号：ES01963002

申请日：2001-09-11

Applicant: BASF AG

Inventor： HASSELWANDER OLIVER ,  KRAEMER KLAUS ,  BALDENIUS KAI-UWE ,  KLATT MARTIN JOCHEN ,  SCHWEIKERT LONI

IPC: A61K31/381 ,  A23L1/30 ,  A61K31/00 ,  A61K31/202 ,  A61K31/385 ,  A61P3/10 ,  A61P9/10 ,  A61P13/12 ,  A61P25/02 ,  A61P27/02

Abstract: Empleo de al menos un ácido lipónico, de un derivado o una sal fisiológicamente aceptable del mismo, y de al menos un compuesto de la fórmula I H3C-(CH2)n1-(CH=CH)n3-(CH2)n2-COOH I en la que n1, n2 significan independientemente entre sí, valores con un número entero desde 3 hasta 9, n3 significa un valor con un número entero desde 2 hasta 6 y el número de los átomos de carbono es 18, 20 o 22, un derivado o sal fisiológicamente aceptable del mismo, para la obtención de agente para el tratamiento de trastornos diabéticos.

公开(公告)号：DK1317264T3

公开(公告)日：2004-11-29

申请号：DK01963002

申请日：2001-09-11

Applicant: BASF AG

Inventor： HASSELWANDER OLIVER ,  BALDENIUS KAI-UWE ,  KRAEMER KLAUS ,  KLATT MARTIN JOCHEN ,  SCHWEIKERT LONI

IPC: A61K31/381 ,  A23L1/30 ,  A61K31/00 ,  A61K31/202 ,  A61K31/385 ,  A61P3/10 ,  A61P9/10 ,  A61P13/12 ,  A61P25/02 ,  A61P27/02

Abstract: The present invention relates to the use of lipoic acid, a physiologically acceptable derivative or salt thereof and one compound of the formula I H3C-(CH2)n1-(CH=CH)n3-(CH2)n2-COOH I in which n1, n2 have, independently of one another, the value of an integer from 3 to 9, n3 has the value of an integer from 2 to 6, and the number of carbon atoms is 18, 20 or 22, a physiologically acceptable derivative or salt thereof, for nutritional supplementation, in functional foods and for therapeutic purposes in the treatment of diabetic disorders. Compositions having a corresponding active ingredient combination, and compositions in the form of commercial packs with corresponding combination products or single-drug products for combined use are also described.

公开(公告)号：DE10318045A1

公开(公告)日：2004-11-04

申请号：DE10318045

申请日：2003-04-17

Applicant: BASF AG

Inventor： KLATT MARTIN JOCHEN ,  HAUNERT FRANK ,  KRAEMER KLAUS

IPC: A23K1/16 ,  A23L1/30 ,  A61K8/36 ,  A61K8/49 ,  A61Q19/00 ,  C07D213/38 ,  C07D339/04 ,  C07D213/02 ,  C07D213/52 ,  A61K31/4425 ,  A61K7/00

Abstract: The invention relates to ammonium salts of alpha-liponic acid of general formula (I): (Lp) (A), formed from alpha-liponic acid (Lp) and amino compounds (A)=of general formula (II) or general formula (III). The invention also relates to a method for producing said salts, and to the use of said salts as constituents in pharmaceutical, dermatological and cosmetic agents, foodstuffs, animal feed supplements or food supplements. The invention also relates to pharmaceutical, dermatological and cosmetic agents, foodstuffs, animal feed supplements or food supplements in which the inventive salts are used.