公开(公告)号：DK1296939T3

公开(公告)日：2006-01-30

申请号：DK01947442

申请日：2001-07-04

Applicant: BASF AG

Inventor： KRAMER ANDREAS ,  HENNINGSEN MICHAEL ,  SIEGEL WOLFGANG ,  SCHROEDER JOCHEN ,  KIEFER MATTHIAS

IPC: C07C249/08 ,  C07B61/00 ,  C07C49/12 ,  C07C249/06 ,  C07C251/40 ,  C07C251/58 ,  C07C251/60

Abstract: The present invention relates to a process for preparing trioxime derivatives of the formula I in which the substituents R 1 and R 2 are identical or different and each is cyano, alkyl, haloalkyl or cycloalkyl, and R 3 and R 4 are identical or different and each is alkyl, haloalkyl, cycloalkyl, alkylcarbonyl or arylalkyl, by the following reaction steps in water without isolation of the intermediates: A) nitrosation of 1,3-diketones of the formula II to give monooximes of the formula III, B) oximation of III with hydroxylamine derivatives of the formula IV H 2 N-OR 3' IV in which R 3' is hydrogen or a group R 3 to give bisoximes of the formula V, C) alkylation of V with alkylating agents or acylation of V with acylating agents to give compounds of the formula VI and D) subsequent oximation of VI with hydroxylamine to give compounds of the formula I.

公开(公告)号：DE10062729A1

公开(公告)日：2002-06-20

申请号：DE10062729

申请日：2000-12-15

Applicant: BASF AG

Inventor： FUNKE FRANK ,  LIANG SHELUE ,  KRAMER ANDREAS ,  STUERMER RAINER ,  HOEHN ARTHUR

IPC: C07B55/00 ,  C07B61/00 ,  C07C209/68 ,  C07C209/88 ,  C07C211/03 ,  C07C213/00 ,  C07C213/02 ,  C07C209/00 ,  C07C217/08 ,  B01J23/80

Abstract: Racemization of optically active amines (I) comprises reaction at elevated temperature in the presence of hydrogen and a supported copper and zinc oxide catalyst. Racemization of optically active amines of formula (I) comprises reaction at elevated temperature in the presence of hydrogen and a supported copper and zinc oxide catalyst. R , R = alkyl, cycloalkyl, aralkyl, aryl, heteroaryl or heterocyclyl; all optionally substituted by alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino or dialkylamino, provided that R and R are different; and R = H or a group as defined for R and R .

公开(公告)号：TR200102337T2

公开(公告)日：2001-12-21

申请号：TR200102337

申请日：1999-05-10

Applicant: BASF AG

Inventor： RIECHERS HARTMUT ,  SIMON JOACHIM ,  HOENN ARTHUR ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/755 ,  C07B55/00 ,  C07B57/00 ,  C07B61/00 ,  C07C209/68 ,  C07C209/88 ,  C07C211/03 ,  C07C213/02 ,  C07C213/08 ,  C07C217/08 ,  C07C9/68

Abstract: A process for the preparation of racemic amines of the formula I where R1 and R2 are different and R1, R2, R3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III and the amine of the formula R3NH2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.

公开(公告)号：NO20013912D0

公开(公告)日：2001-08-10

申请号：NO20013912

申请日：2001-08-10

Applicant: BASF AG

Inventor： RIECHERS HARTMUT ,  SIMON JOACHIM ,  HOEHN ARTHUR ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/755 ,  C07B55/00 ,  C07B57/00 ,  C07B61/00 ,  C07C209/68 ,  C07C209/88 ,  C07C211/03 ,  C07C213/02 ,  C07C213/08 ,  C07C217/08

Abstract: A process for the preparation of racemic amines of the formula I where R1 and R2 are different and R1, R2, R3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III and the amine of the formula R3NH2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.

公开(公告)号：NO20013912A

公开(公告)日：2001-08-10

申请号：NO20013912

申请日：2001-08-10

Applicant: BASF AG

Inventor： RIECHERS HARTMUT ,  SIMON JOACHIM ,  HOEHN ARTHUR ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/755 ,  C07B55/00 ,  C07B57/00 ,  C07B61/00 ,  C07C209/68 ,  C07C211/03 ,  C07C213/02 ,  C07C213/08 ,  C07C217/08 ,  C07C209/88

CPC classification number: C07C213/08 ,  C07C209/68 ,  C07C211/03 ,  C07C217/08

公开(公告)号：NO324896B1

公开(公告)日：2007-12-27

申请号：NO20013912

申请日：2001-08-10

Applicant: BASF AG

Inventor： HOHN ARTHUR ,  RIECHERS HARTMUT ,  SIMON JOACHIM ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/755 ,  C07C209/68 ,  C07B55/00 ,  C07B57/00 ,  C07B61/00 ,  C07C209/88 ,  C07C211/03 ,  C07C213/02 ,  C07C213/08 ,  C07C217/08

Abstract: A process for the preparation of racemic amines of the formula I where R1 and R2 are different and R1, R2, R3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III and the amine of the formula R3NH2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.

公开(公告)号：AT363461T

公开(公告)日：2007-06-15

申请号：AT04763087

申请日：2004-07-03

Applicant: BASF AG

Inventor： VICARI MAXIMILIAN ,  RUDLOFF MARTIN ,  KRAMER ANDREAS ,  DREWS RONALD

IPC: C07C29/42 ,  C07C33/042

Abstract: In the production of propargyl alcohol (I) by conversion of an aqueous formaldehyde solution containing acetylene in presence of a catalyst containing copper acetylide at 1-15 (preferably 3-7) bars and 70-120[deg]C without formation of a coherent gas phase, the aqueous formaldehyde solution contains an organic solvent for acetylene and the catalyst is arranged in a fluidized bed.

公开(公告)号：AU769005B2

公开(公告)日：2004-01-15

申请号：AU4140899

申请日：1999-05-10

Applicant: BASF AG

Inventor： RIECHERS HARTMUT ,  SIMON JOACHIM ,  HOEHN ARTHUR ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/755 ,  C07B55/00 ,  C07B57/00 ,  C07B61/00 ,  C07C209/68 ,  C07C209/88 ,  C07C211/03 ,  C07C213/02 ,  C07C213/08 ,  C07C217/08

Abstract: A process for the preparation of racemic amines of the formula I where R1 and R2 are different and R1, R2, R3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III and the amine of the formula R3NH2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.

公开(公告)号：DE59907224D1

公开(公告)日：2003-11-06

申请号：DE59907224

申请日：1999-04-28

Applicant: BASF AG

Inventor： RIECHERS HARTMUT ,  SIMON JOACHIM ,  HOEHN ARTHUR ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/72 ,  B01J23/755 ,  B01J37/18 ,  C07B55/00 ,  C07B61/00 ,  C07C209/00 ,  C07C209/68 ,  C07C211/00 ,  C07C211/07 ,  C07C213/08 ,  C07C217/08

Abstract: Optically active amines are racemized by reaction of the optically active amine in the gas phase at elevated temperature in the presence of hydrogen and a hydrogenation or dehydrogenation catalyst.

公开(公告)号：DE19905838A1

公开(公告)日：2000-08-17

申请号：DE19905838

申请日：1999-02-12

Applicant: BASF AG

Inventor： RIECHERS HARTMUT ,  SIMON JOACHIM ,  HOEHN ARTHUR ,  KRAMER ANDREAS ,  FUNKE FRANK ,  SIEGEL WOLFGANG ,  NUEBLING CHRISTOPH

IPC: B01J23/88 ,  B01J23/755 ,  C07B55/00 ,  C07B57/00 ,  C07B61/00 ,  C07C209/00 ,  C07C209/68 ,  C07C209/86 ,  C07C209/88 ,  C07C211/03 ,  C07C213/08 ,  C07C217/08

Abstract: The invention relates to a method for the racemization of optically active amines by reacting the optically active amine in the presence of hydrogen and of a hydrogenation or dehydrogenation catalyst at an elevated temperature. According to the invention the reaction is carried out in the liquid phase and the catalyst contains the catalytically active components copper, silver, iron, cobalt, nickel, ruthenium, rhodium, palladium, osmium, iridium and/or platinum as well as a carrier material chosen from the group of aluminium oxide, zirconium dioxide, titanium dioxide, carbon and/or oxygen-containing silicium compounds.