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    11.
    发明专利
    未知

    公开(公告)号：EE200200443A

    公开(公告)日：2003-12-15

    申请号：EEP200200443

    申请日：2001-02-08

    Applicant: BASF AG

    Inventor： HEINZ ERNST ,  ZANK THORSTEN ,  ZAEHRINGER ULRICH ,  LERCHL JENS ,  RENZ ANDREAS

    IPC: A01H5/00 ,  A01K67/027 ,  A23K1/16 ,  A23L1/30 ,  A61K8/30 ,  A61K8/36 ,  A61K8/92 ,  A61K31/201 ,  A61K31/202 ,  A61P3/02 ,  A61P3/06 ,  A61P9/10 ,  A61P29/00 ,  C07K16/40 ,  C11C3/00 ,  C12N9/00 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12N15/82 ,  C12P7/64 ,  C12Q1/02 ,  A61K38/45 ,  C11B1/00 ,  C11C1/00 ,  C12Q1/48 ,  G01N33/573

    Abstract: The invention relates to novel elongase genes with the sequences stated in sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or their homologs, derivatives or analogs, to a gene construct comprising this gene or its homologs, derivatives and analogs, and to its use. The invention also relates to vectors or transgenic organisms comprising an elongase gene with the sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or its homologs, derivatives and analogs. The invention furthermore relates to the use of the elongase gene sequences alone or in combination with further elongases and/or further fatty acid biosynthesis genes. The present invention relates to a novel elongase gene with the sequence SEQ ID NO:1 or its homologs, derivatives and analogs. Furthermore, the invention relates to a process for the preparation of polyunsaturated fatty acids and to a process for introducing DNA into organisms which produce large amounts of oils and, in particular, oils with a high content of unsaturated fatty acids. Moreover, the invention relates to an oil and/or a fatty acid preparation with a higher content of polyunsaturated fatty acids with at least two double bonds and/or a triacylglycerol preparation with a higher content of polyunsaturated fatty acids with at least two double bonds.

    New elongase gene extends 16, 18 and 20 carbon fatty acids, useful to manipulate plants to produce polyunsaturated fatty acids for the foodstuffs, cosmetics and pharmaceutical industries
    14.
    发明专利
    New elongase gene extends 16, 18 and 20 carbon fatty acids, useful to manipulate plants to produce polyunsaturated fatty acids for the foodstuffs, cosmetics and pharmaceutical industries 未知

    公开(公告)号：DE10063387A1

    公开(公告)日：2002-09-12

    申请号：DE10063387

    申请日：2000-12-19

    Applicant: BASF AG

    Inventor： HEINZ ERNST ,  ZANK THORSTEN ,  RENZ ANDREAS ,  LERCHL JENS

    IPC: C12N9/10 ,  C12N15/29 ,  C12N15/82 ,  C12P7/64 ,  A01H5/00 ,  C07H21/04 ,  C07K14/415 ,  C07K16/00 ,  C12N1/00 ,  C12N9/00 ,  C12N15/52 ,  C12Q1/00

    Abstract: An isolated nucleic acid from a plant or algae which encodes a polypeptide which extends a C16, C18 or C20 fatty acid having at least two double bonds by at least two carbon atoms, is new. Independent claims are also included for the following: (1) an isolated nucleic acid encoding a polypeptide which extends a C16, C18 or C20 fatty acid having at least two double bonds by at least two carbon atoms, and having the 1192, 687, 955 or 708 base pair (bp) sequence fully defined in the specification, a genetic code degenerate or derivative of one of those sequences, or encoding the 290, 195, 297 or 214 amino acid sequence fully defined in the specification, or a sequence with at least 50% homology to one of those sequences where the enzymatic activity is not substantially reduced; (2) a gene construct comprising one of the above nucleic acids linked to one or more regulatory sequences; (3) amino acid sequences encoded by the above nucleic acids or construct; (4) a vector comprising the above nucleic acids or construct; (5) an organism comprising the above nucleic acids, construct or vector; (6) an antibody which specifically binds to the product of the above nucleic acids; (7) an antisense nucleic acid molecule complementary to one of the above nucleic acids; (8) producing polyunsaturated fatty acids (PUFAs), comprising breeding organisms containing the above nucleic acids, construct or vector, encoding a polypeptide which extends a C16, C18 or C20 fatty acid having at least two double bonds by at least two carbon atoms, under PUFA forming conditions; (9) an oil, lipid, fatty acid or its fraction, produced by the above method; (10) an oil, lipid or fatty acid composition containing PUFAs from transgenic plants, preferably where the transgenic plant comprises the above nucleic acids, construct or vector; (11) identifying an elongase (ant)agonist comprising contacting cells expressing the polypeptide of the invention with a candidate compound, testing PSE activity and comparing activity with a control standard.

    15.
    发明专利
    未知

    公开(公告)号：NO20023757D0

    公开(公告)日：2002-08-08

    申请号：NO20023757

    申请日：2002-08-08

    Applicant: BASF AG

    Inventor： HEINZ ERNST ,  ZANK THORSTEN ,  ZAEHRINGER ULRICH ,  LERCHL JENS ,  RENZ ANDREAS

    IPC: A01H5/00 ,  A01K67/027 ,  A23K1/16 ,  A23L1/30 ,  A61K8/30 ,  A61K8/36 ,  A61K8/92 ,  A61K31/201 ,  A61K31/202 ,  A61P3/02 ,  A61P3/06 ,  A61P9/10 ,  A61P29/00 ,  C07K16/40 ,  C11C3/00 ,  C12N9/00 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12N15/82 ,  C12P7/64 ,  C12Q1/02 ,  C12N

    Abstract: The invention relates to novel elongase genes with the sequences stated in sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or their homologs, derivatives or analogs, to a gene construct comprising this gene or its homologs, derivatives and analogs, and to its use. The invention also relates to vectors or transgenic organisms comprising an elongase gene with the sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or its homologs, derivatives and analogs. The invention furthermore relates to the use of the elongase gene sequences alone or in combination with further elongases and/or further fatty acid biosynthesis genes. The present invention relates to a novel elongase gene with the sequence SEQ ID NO:1 or its homologs, derivatives and analogs. Furthermore, the invention relates to a process for the preparation of polyunsaturated fatty acids and to a process for introducing DNA into organisms which produce large amounts of oils and, in particular, oils with a high content of unsaturated fatty acids. Moreover, the invention relates to an oil and/or a fatty acid preparation with a higher content of polyunsaturated fatty acids with at least two double bonds and/or a triacylglycerol preparation with a higher content of polyunsaturated fatty acids with at least two double bonds.

    20.
    发明专利
    未知

    公开(公告)号：BR0108198A

    公开(公告)日：2003-03-25

    申请号：BR0108198

    申请日：2001-02-08

    Applicant: BASF AG

    Inventor： HEINZ ERNST ,  ZANK THORSTEN ,  ZOHRINGER ULRICH ,  LERCHL JENS ,  RENZ ANDREAS

    IPC: A01H5/00 ,  A01K67/027 ,  A23K1/16 ,  A23L1/30 ,  A61K8/30 ,  A61K8/36 ,  A61K8/92 ,  A61K31/201 ,  A61K31/202 ,  A61P3/02 ,  A61P3/06 ,  A61P9/10 ,  A61P29/00 ,  C07K16/40 ,  C11C3/00 ,  C12N9/00 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12N15/82 ,  C12P7/64 ,  C12Q1/02 ,  C11B1/00 ,  C11C1/00 ,  G01N33/573 ,  C12Q1/48 ,  A61K38/45

    Abstract: The invention relates to novel elongase genes with the sequences stated in sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or their homologs, derivatives or analogs, to a gene construct comprising this gene or its homologs, derivatives and analogs, and to its use. The invention also relates to vectors or transgenic organisms comprising an elongase gene with the sequence SEQ ID NO:1, SEQ ID NO: 3, SEQ ID NO: 5 and SEQ ID NO: 7 or its homologs, derivatives and analogs. The invention furthermore relates to the use of the elongase gene sequences alone or in combination with further elongases and/or further fatty acid biosynthesis genes. The present invention relates to a novel elongase gene with the sequence SEQ ID NO:1 or its homologs, derivatives and analogs. Furthermore, the invention relates to a process for the preparation of polyunsaturated fatty acids and to a process for introducing DNA into organisms which produce large amounts of oils and, in particular, oils with a high content of unsaturated fatty acids. Moreover, the invention relates to an oil and/or a fatty acid preparation with a higher content of polyunsaturated fatty acids with at least two double bonds and/or a triacylglycerol preparation with a higher content of polyunsaturated fatty acids with at least two double bonds.

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