公开(公告)号：DE69110658D1

公开(公告)日：1995-07-27

申请号：DE69110658

申请日：1991-10-30

Applicant: BAXTER DIAGNOSTICS INC

Inventor： MORRIS ROGER ,  BASCOMB SHOSHANA ,  OLSON CAROLYN

IPC: C12Q1/26 ,  G01N21/17 ,  G01N21/53 ,  G01N21/78

Abstract: A process to determine the concentration of any substance in a colorimetric, turbidimetric or nephelometric reaction using a fluorometric detector to measure fluorescence intensity. In particular, a change in color can be monitored by observing the measurement of fluorescence intensity of a fluorophore in an inert matrix. The absorption spectrum of the chromophore may overlap the excitation and/or emission spectrum of the fluorophore, thereby allowing the change in fluorescence to be related to the intensity of color in the reaction and thus related to the quantity of the substance of interest.

公开(公告)号：AU652423B2

公开(公告)日：1994-08-25

申请号：AU1263892

申请日：1991-12-23

Applicant: BAXTER DIAGNOSTICS INC

Inventor： MORRIS ROGER JAMES ,  BASCOMB SHOSHANA ,  BOBOLIS JAMIE ,  SHERMAN DAVID ,  OLSEN CAROLYN SHELCHUK

IPC: C12M1/34 ,  C12Q1/06 ,  G01N20060101 ,  G01N21/27 ,  G01N21/64 ,  G01N21/78 ,  G01N21/80 ,  G01N33/49 ,  C12Q1/08 ,  G01N33/52

公开(公告)号：NO923436L

公开(公告)日：1992-09-03

申请号：NO923436

申请日：1992-09-03

Applicant: BAXTER DIAGNOSTICS INC

Inventor： MORRIS ROGER JAMES ,  BASCOMB SHOSHANA ,  BOBOLIS JAMIE ,  SHERMAN DAVID ,  OLSON CAROLYN SHELCHUK

IPC: C12M1/34 ,  C12Q1/06 ,  G01N20060101 ,  G01N21/27 ,  G01N21/64 ,  G01N21/78 ,  G01N21/80 ,  G01N33/49 ,  G01N

公开(公告)号：CA2075824A1

公开(公告)日：1992-06-29

申请号：CA2075824

申请日：1991-12-23

Applicant: BAXTER DIAGNOSTICS INC

Inventor： BADAL ROBERT ,  KELLEY ROGER ,  SAND THEODORE T ,  BASCOMB SHOSHANA

IPC: C12Q1/04 ,  C12Q1/18 ,  C12Q1/20

公开(公告)号：EP0516814A4

公开(公告)日：1994-06-01

申请号：EP92902996

申请日：1991-12-23

Applicant: BAXTER DIAGNOSTICS INC

Inventor： BADAL ROBERT ,  KELLEY ROGER ,  SAND THEODORE T ,  BASCOMB SHOSHANA

IPC: C12Q1/04 ,  C12Q1/18

CPC classification number: C12Q1/04 ,  C12Q1/18 ,  C12Q2337/22 ,  Y10S435/968 ,  Y10S436/80

Abstract: This invention relates to a method to determine susceptibility to antimicrobial agents of a majority of clinically significant Gram positive organisms. This invention also relates to a mixture of fluorogenic substrates used to detect the growth of Gram positive Bacteria.