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公开(公告)号：CA1316822C
公开(公告)日：1993-04-27
申请号：CA579483
申请日：1988-10-06
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W
Abstract: A METHOD FOR WETTING A PLASMAPHERESIS FILTER WITH ANTICOAGULANT A method of wetting a plasmapheresis filter with anticoagulant in a plasmapheresis system having a venepuncture needle, a plasma separation device connected in series by a fluid conduit, including operating the system such that an initial limited volume charge of anticoagulant is introduced into the conduit (for wetting the filter of the separation device) in advance of whole blood flowing from the donor towards to the separation device (and pushing the anticoagulant charge ahead of the whole blood into the separation device).
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公开(公告)号：CA2064694C
公开(公告)日：2001-12-25
申请号：CA2064694
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： HWANG YEAN YOW , RITCHEY BRIAN , SCHOENDORFER DONALD W
Abstract: Method and apparatus are provided for machine separation of blood into blood components, wherein a preselected fluid such as anticoagulant is added to at least two different locations (16, 112) through the fluid flow path of the sec (10), in order to promote the different functional characteristics in different blood components. The method results in reduced incidence of citrate reaction in the blood donor and increased platelet yield in platelet rich plasma (60) collected during the procedure.
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公开(公告)号：DE69132172D1
公开(公告)日：2000-06-08
申请号：DE69132172
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W
Abstract: In the method, either no anticoagulant solution, or an aliquot of anticoagulant solution is added to whole blood upstream of a separator. Anticoagulant solution is added to a separated component downstream of the separator.
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公开(公告)号：DE69129419T2
公开(公告)日：1999-01-07
申请号：DE69129419
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： HWANG YEAN YOW , RITCHEY BRIAN , SCHOENDORFER DONALD W
Abstract: Whole blood is separated into components in a separator (46) to produce platelet-rich plasma in a first operation in which a low amount of anticoagulant is added to the whole blood sufficient to prevent coagulation. Further anticoagulant is passed through the separator (46) after the whole blood flow has been stopped, so as to add further anticoagulant to the platelet-rich plasma to promote storage. This permits a higher platelet yield to be obtained in the separator.
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公开(公告)号：DE69129419D1
公开(公告)日：1998-06-18
申请号：DE69129419
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： HWANG YEAN YOW , RITCHEY BRIAN , SCHOENDORFER DONALD W
Abstract: Whole blood is separated into components in a separator (46) to produce platelet-rich plasma in a first operation in which a low amount of anticoagulant is added to the whole blood sufficient to prevent coagulation. Further anticoagulant is passed through the separator (46) after the whole blood flow has been stopped, so as to add further anticoagulant to the platelet-rich plasma to promote storage. This permits a higher platelet yield to be obtained in the separator.
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Patent Agency Ranking
公开(公告)号：AU1295388A
公开(公告)日：1988-08-24
申请号：AU1295388
申请日：1988-01-29
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W , WILLIAMSON WARREN P
Abstract: A limb stimulator is engaged with a lower portion of a patient's limb for facilitating sustained venous blood flow therefrom toward a phlebotomy needle when the stimulator is activated. The stimulator may be an inflatable squeeze bulb adapted to engage a human hand and to be squeezed thereby when inflated. The stimulator may also, or alternatively, include a pressurizable member substantially surrounding a lower portion of the limb and adapted to apply external pressure thereto when periodically pressurized so as to periodically (e.g., in approximate synchronism with natural pulsitile blood movements in the limb) express venous blood upwardly through the limb to the needle. Inflation of the hand-held squeeze bulb serves as a tactile stimulus to the patient to assist in venous blood movements towards the needle by muscle and tendon flexure in the lower part of the limb and may also be periodically activated (e.g., in approximate synchronism with natural pulsatile blood movements in the limb).
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17.发明专利
公开(公告)号：CA2064712C
公开(公告)日：1999-04-06
申请号：CA2064712
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W
Abstract: Method and apparatus for machine separation of blood and blood components that u tilizes improved administration of anticoagulant to the red cell suspension output. Anticoagulant (20) is added to incoming whole blood (13) in an amount sufficient to prevent clotting of the whole blood in the flow path upstream of the blood co mponent separator (46), but in an amount insufficient to prevent clotting of the red cell suspension created by the separator. Anticoa gulant (20) is added to the red cell suspension downstream (50) of the separator (46) in order to prevent clotting. By adding an additional aliquot of anticoagulant to the red cell suspension, the amount of anticoagulant added to whole blood before separation c an be reduced or eliminated, resulting in an increase in platelet yield during the blood component separation step.
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公开(公告)号：DE3854927T2
公开(公告)日：1996-09-05
申请号：DE3854927
申请日：1988-11-22
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W , PRINCE PAUL R
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公开(公告)号：AU8051591A
公开(公告)日：1992-01-07
申请号：AU8051591
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： BENJAMIN GRANT S , RITCHEY BRIAN , SCHOENDORFER DONALD W
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公开(公告)号：CA2064757A1
公开(公告)日：1991-12-15
申请号：CA2064757
申请日：1991-06-12
Applicant: BAXTER INT
Inventor： BENJAMIN GRANT S , RITCHEY BRIAN , SCHOENDORFER DONALD W
Abstract: 2064757 9119522 PCTABS00008 A needle assembly (60) is provided for withdrawing and returning blood and blood components to a patient or other donor, especially in a machine-assisted blood component separating operation, whereby the incidence of clotting and the size of clots formed in the needle is greatly minimized. The needle assembly is especially useful in situations where only low levels of anticoagulant are added to the extracorporeal blood, which, but for the improved needle assembly, would exacerbate the problem of clot formation at the needle. The assembly (60) includes attached tubing (66) having an internal diameter adjacent the blunt end (72) of the needle (68) that is equal to, or preferably less than, the internal diameter of the needle.
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