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公开(公告)号：JP2001259021A
公开(公告)日：2001-09-25
申请号：JP2001049968
申请日：2001-02-26
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , BROWN RICHARD I , WILLIAMSON WARREN P
Abstract: PROBLEM TO BE SOLVED: To furthermore improve an online system used for blood component collection to collect specific cell components, such as blood platelets, from the whole blood of a donor by using an extracorporeal circulation circuit and to return the remaining components to the donor. SOLUTION: In the system, separates the whole blood is separated into red blood cells and a blood platelet-rich plasma in a first step and the blood platelet rich plasma is separated into a blood platelet concentrate and a blood platelet poor plasma in a second step. The blood platelet concentrate is made to remain in a second-step separator and part of the blood platelet poor plasma is held in the system. The balance is returned together with the red blood cells to the donor. The held blood platelet poor plasma is used for resuspension of the blood platelet concentrate.
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公开(公告)号：JP2001269400A
公开(公告)日：2001-10-02
申请号：JP2001049882
申请日：2001-02-26
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , BROWN RICHARD I , WILLIAMSON WARREN P
Abstract: PROBLEM TO BE SOLVED: To provide a system for obtaining a platelet-rich concentrate with a reduced number of leukocytes in the on-line separation of blood by extracorporeal circulation. SOLUTION: A separation device for separating complete blood counts into erythrocytes and a platelet suspension, a filtering device for reducing the number of leukocytes in the platelet suspension, and another separation device for separating the platelet suspension into the platelet-rich concentrate with a reduced number of leukocytes are arranged in series within a flow passage connectable to the circulatory system of a donor to provide the system controlling the separation process by means of a control device which maintains communication between the flow passage and the donor's circulatory system.
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公开(公告)号：EP0685037A4
公开(公告)日：1996-02-28
申请号：EP94913914
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： CHAPMAN ARTHUR S , WILLIAMSON WARREN P
CPC classification number: F04B43/1276 , A61M1/30 , A61M1/303 , A61M1/3693 , A61M1/3696 , A61M2205/12 , F02B2075/025
Abstract: A peristaltic pump includes a pump race for receiving a flexible tubing. A rotatable pump rotor (292) carries at least one roller (300) for contacting the tubing (134/136). A roller locating mechanism (306) moves the pump roller between a retracted position for free contact with the tubing and an extended position making operative contact with the tubing. A controller (246) operates the pump (i) in a pumping mode, during which the rotor (292) is rotated with the roller (300) located in its extended position, and (ii) in a valving mode, during which rotation of the rotor is terminated and the roller is selectively moved between its extended position to block fluid flow through the tubing and its retracted position to permit fluid flow through the tubing. The pump thus provides a peristaltic pump pumping function, as well as serving as a valve element.
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公开(公告)号：EP0683694A4
公开(公告)日：1998-08-12
申请号：EP94920649
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , WILLIAMSON WARREN P , DIPERNA PAUL
CPC classification number: B04B5/0442 , B04B2005/045 , F02B2075/025
Abstract: A centrifuge (10) comprising a yoke element (348) that rotates about a rotational axis (344) and a processing chamber (230) having an axis. The processing chamber includes a bowl element (374), a spool element (376), and a mechanism (360) for joining spool and bowl elements for relative movement between a mutually cooperating position for centrifugal processing and a mutually separated position for loading. A hinge (370) attaches the processing chamber (230) to the yoke element (348) for pivotal movement between an operating position and an access position. In the operating position, the spool (376) and bowl elements (374) are in their mutually cooperating position and oriented for rotation with the yoke element about the rotational axis. In the access position, the processing chamber axis lies outside the axis of rotation and the spool (376) and the bowl elements (374) are oriented for movement from their mutually cooperating position into their mutually separated position.
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5.发明公开BLOOD PROCESSING SYSTEMS USING A PERISTALTIC PUMP MODULE WITH VALVE AND SENSING STATION FOR OPERATING A PERISTALTIC PUMP TUBE CASSETTE 失效阀门和灌装工位血液处理系统的蠕动泵模块用于驱动水泵管道盒蠕动
公开(公告)号：EP0686237A4
公开(公告)日：1996-02-28
申请号：EP94921160
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： DENNEHEY T MICHAEL , BROWN RICHARD I , WILLIAMSON WARREN P
CPC classification number: A61M1/3693 , A61M1/30 , A61M1/303 , A61M1/3696 , F02B2075/025 , F04B43/1253 , F04B43/1292 , F04B2205/05
Abstract: A blood processing assembly (14) includes a separation element (12) for separating blood from a source into a first component and a second component. The assembly also includes a fluid path (18) that conveys blood between the source and the separation element. The fluid path includes one or more in-line cassettes (22A/B/C) that serve in association with peristaltic pumps to centralize pumping and valving functions of the system. The cassettes also serve to segregate the flow paths of the blood components from each other.
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Patent Agency Ranking
公开(公告)号：EP0300026A4
公开(公告)日：1990-05-14
申请号：EP88901721
申请日：1988-01-29
Applicant: BAXTER INT
Inventor： WILLIAMSON WARREN P , SCHOENDORFER DONALD W
CPC classification number: A61H9/0078 , A61H2201/165 , A61H2230/06 , A61M1/02 , A61M2230/04 , A61M2230/005
Abstract: A limb stimulator is engaged with a lower portion of a patient's limb for facilitating sustained venous blood flow therefrom toward a phlebotomy needle (14). The stimulator may be an inflatable squeeze bulb (100) adapted to engage a human hand and to be squeezed thereby when inflated. The stimulator may also, or alternatively, include a pressurizable member (200) substantially surrounding a lower portion of the limb and adapted to apply external pressure thereto when periodically pressurized so as to periodically (e.g., in approximate synchronism with natural pulsatile blood movements in the limb) express venous blood upwardly through the limb to the needle (14). Inflation of the hand-held squeeze bulb (100) serves as a tactile stimulus to the patient to assist in venous blood movements towards the needle by muscle and tendon flexure in the lower part of the limb and may also be periodically activated.
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公开(公告)号：DE69431494T2
公开(公告)日：2003-06-26
申请号：DE69431494
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： DENNEHEY MICHAEL T , BROWN RICHARD I , WILLIAMSON WARREN P
Abstract: A blood processing assembly is described. The assembly comprises a separation element (16) for separating blood from a source and a fluid path (18) for conveying blood from the source to the separation element (16). The fluid path (18) includes an in-line cassette (22) having a housing (110) defining an interior, first (T4) and second (T5) pump ports on the housing (110), a first flexible tubing loop (134) extending between the first and second pump ports externally of the housing for engagement with an external peristaltic pumping element (292), a liquid port (T1 to T3,T8 to T10) on the housing attachable to a length of tubing (154) that extends externally of the housing and forms a part of the associated fluid path (18), liquid passages (F1 to F19) formed within the housing and communicating with the liquid port, the first pump port and the second pump port, and valve means (V1 to V10) formed within the housing for controlling liquid flow through the liquid passages and through the associated fluid path. The cassette also comprises a pressure sensing chamber (S1 to S4) which is formed within the housing and communicates with at least one liquid passage (F1 to F19). The sensing chamber (S1 to S4) includes means for transmitting liquid pressure present within the liquid passage to an external sensing element (PS1 to PS4).
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公开(公告)号：AU3334893A
公开(公告)日：1993-07-28
申请号：AU3334893
申请日：1992-12-23
Applicant: BAXTER INT
Inventor： WILLIAMSON WARREN P
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公开(公告)号：DE69431494D1
公开(公告)日：2002-11-07
申请号：DE69431494
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： DENNEHEY MICHAEL T , BROWN RICHARD I , WILLIAMSON WARREN P
Abstract: A blood processing assembly is described. The assembly comprises a separation element (16) for separating blood from a source and a fluid path (18) for conveying blood from the source to the separation element (16). The fluid path (18) includes an in-line cassette (22) having a housing (110) defining an interior, first (T4) and second (T5) pump ports on the housing (110), a first flexible tubing loop (134) extending between the first and second pump ports externally of the housing for engagement with an external peristaltic pumping element (292), a liquid port (T1 to T3,T8 to T10) on the housing attachable to a length of tubing (154) that extends externally of the housing and forms a part of the associated fluid path (18), liquid passages (F1 to F19) formed within the housing and communicating with the liquid port, the first pump port and the second pump port, and valve means (V1 to V10) formed within the housing for controlling liquid flow through the liquid passages and through the associated fluid path. The cassette also comprises a pressure sensing chamber (S1 to S4) which is formed within the housing and communicates with at least one liquid passage (F1 to F19). The sensing chamber (S1 to S4) includes means for transmitting liquid pressure present within the liquid passage to an external sensing element (PS1 to PS4).
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公开(公告)号：CA2156391A1
公开(公告)日：1995-06-29
申请号：CA2156391
申请日：1994-03-17
Applicant: BAXTER INT
Inventor： BROWN RICHARD I , WILLIAMSON WARREN P , DIPERNA PAUL
Abstract: A centrifuge (10) comprising a yoke element (348) that rotates about a rotational axis (344) and a processing chamber (230) having an axis. The processing chamber includes a bowl element (374), a spool element (376), and a mechanism (360) for joining spool and bowl elements for relative movement between a mutually cooperating position for centrifugal processing and a mutually separated position for loading. A hinge (370) attaches the processing chamber (230) to the yoke element (348) for pivotal movement between an operating position and an access position. In the operating position, the spool (376) and bowl elements (374) are in their mutually cooperating position and oriented for rotation with the yoke element about the rotational axis. In the access position, the processing chamber axis lies outside the axis of rotation and the spool (376) and the bowl elements (374) are oriented for movement from their mutually cooperating position into their mutually separated position.
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