Abstract:
Membranes are made from polymers and heat treated so that they have at least two zones with pores of different sizes. Pores with a smaller size have a lower molecular weight cut off than pores with a larger size. Zones with pores of different sizes may also be made by coating portions of membranes with polymer coatings. Membranes with pores of different sizes may be used in dialyzers for hemofiltration, hemodiafiltration, and other hemodialysis procedures. The membranes may also be used in other separation processes.
Abstract:
A medical device, such as a vascular access device, is disclosed for prov iding access to a medical fluid flow path for the introduction or withdrawal of medical fluids to and from the flow path. The access device includes an indicator for providing a visual indication when the access device has been exposed to an antiseptic agent.
Abstract:
Sistema de infusión (2) que comprende: una vía de paso (4, 8, 201, 203) para permitir el flujo de un fluido; caracterizado por un dispositivo para indicar el cebado del sistema de infusión que reviste la vía de paso, incluyendo dicho dispositivo: una membrana (24, 30, 130, 230) que presenta una primera característica visual cuando está seca y una segunda característica visual cuando está mojada, estando dispuesta la membrana para ser expuesta al líquido que fluye a lo largo de la vía de paso; y una superficie (22, 28, 128, 228) cubierta por la membrana, incluyendo esta superficie indicios que se hacen visibles a través de la membrana cuando ésta se moja con dicho líquido.
Abstract:
A device for indicating priming of an infusion line includes: a microporous membrane that blocks transmission of light therethrough when dry and that allows transmission of light therethrough when wet; a source of a light signal covered by the microporous membrane, light from the source of the light signal being transmitted through the microporous membrane upon the microporous membrane becoming wet; and a sensor 354 that senses light from the source of the light signal, the sensor 354 being separated from the source of the light signal by at least the microporous membrane, and in electrical communication with a controller 350 in communication with an alarm 352 which is activated by the controller 350 upon detection by the sensor of light from the source of the light signal. -r > 'N> 'z. n \ > C' V ,~,, N~ t~ * "N"> \N N
Abstract:
A priming indicator for a fluid infusion system includes a luer cap (20) or other component of the infusion system having an indicator surface (22) covered by a membrane (24). The membrane exhibits a first visual characteristic, such as being opaque, when dry and exhibits a second characteristic, such as becoming less opaque, when wet. Once the membrane becomes wet, indicia on the surface, which may be provided on a rod at least partially covered by the membrane, becomes visible, thereby indicating an intravenous tube to which the luer cap is secured has been primed or is nearly primed. The indicator may alternately be employed at an upstream end of an infusion set, such as at the port of a medical bag providing a supply of fluid, to indicate a low level of fluid in the medical bag.
Abstract:
A priming indicator for a fluid infusion system includes a luer cap or other component of the infusion system having an indicator surface covered by a membrane. The membrane exhibits a first visual characteristic, such as being opaque, when dry and exhibits a second characteristic, such as becoming less opaque, when wet. Once the membrane becomes wet, indicia on the surface, which may be provided on a rod at least partially covered by the membrane, becomes visible, thereby indicating an intravenous tube to which the luer cap is secured has been primed or is nearly primed. The indicator may alternately be employed at an upstream end of an infusion set, such as at the port of a medical bag providing a supply of fluid, to indicate a low level of fluid in the medical bag.
Abstract:
Membranes and methods for making membranes are disclosed. The membranes (10) include a polymeric matrix (16) and a particulate material immobilized within the matrix. The membrane may further include a skin layer (19) having randomly spaced surface pores (21). The membranes may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.
Abstract:
The present invention relates to a process for preparing submicron sized nanoparticles of a poorly water soluble compound by sonicating to evaporate a portion of the organic phase or by lyophilizing a dispersion or microdispersion of a multiphase system having an organic phase and an aqueous phase, the organic phase havingthe poorly water soluble organic compound therein. The method is preferably used to prepare nanoparticles of a poorly water soluble, pharmaceutically active compound suitable for in vivo delivery, particularly by parenteral routes.