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公开(公告)号：AU519925B2
公开(公告)日：1982-01-07
申请号：AU4113978
申请日：1978-10-27
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , SMITH H
IPC: A61K31/41 , A61P37/08 , C07D20060101 , C07D249/16 , C07D249/22 , C07D249/24 , C07C87/64 , C07C103/34
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公开(公告)号：AU6967381A
公开(公告)日：1981-10-29
申请号：AU6967381
申请日：1981-04-21
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , TEDDER J M , SMITH H
IPC: C07D249/22 , A61K31/495
Abstract: Compounds of formula (I):wherein R is hydrogen, halogen, C 1-4 alkyl or C 1-4 alkoxy; R 1 is hydrogen or C 1-6 alkyl; and n is 1 to 6 and pharmaceutically acceptable salts thereof; pharmaceutical compositions containing them; a process for their preparation; and their use in treating allergy.
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公开(公告)号：SE7711779A
公开(公告)日：1977-10-19
申请号：SE7711779
申请日：1977-10-19
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , CANTELLO B C C , SMITH H
IPC: C07D217/26 , C07D311/76 , C07D335/06
CPC classification number: C07D335/06 , C07D217/26 , C07D311/76 , Y10S514/826
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公开(公告)号：NO135632B
公开(公告)日：1977-01-24
申请号：NO465572
申请日：1972-12-15
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , SMITH H
IPC: A61K31/04 , A61K31/12 , C07C45/48 , C07C49/67 , C07C49/675 , C07C49/697 , C07C49/84 , C07C62/38 , C07C79/36
Abstract: 2-Nitroindane-1,3-dione derivatives are useful in the prophylaxis and treatment of asthma, hay fever and also in the treatment of rhinitis.
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公开(公告)号：SE7505865L
公开(公告)日：1975-12-01
申请号：SE7505865
申请日：1975-05-22
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , CANTELLO B C C , SMITH H
IPC: A61K31/06 , A61K31/12 , C07C45/45 , C07C45/46 , C07C46/00 , C07C46/02 , C07C49/67 , C07C49/675 , C07C49/697 , C07C49/755 , C07C50/26 , C07C50/32 , C07C50/34 , C07C67/00 , C07C201/00 , C07C205/46 , C07C205/48 , C07C79/36
Abstract: Substituted naphthoquinones of the formula (I) and pharmaceutically acceptable salts thereof wherein R1, R2, R3 and R4 represent alkyl, aryl, alkoxy, hydroxy, hydrogen or halogen or any two of the groups R1, R2, R3 and R4 taken together complete a carbocyclic ring, have useful anti-allergy activity in mammals.
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Patent Agency Ranking
公开(公告)号：DK193675A
公开(公告)日：1975-11-05
申请号：DK193675
申请日：1975-05-02
Applicant: BEECHAM GROUP LTD
Inventor： DOYLE F P , CANTELLO B C C , BUCKLE D R , SMITH H
IPC: C07D311/56 , A61K31/35 , A61K31/37 , C07C45/46 , C07C46/00 , C07C46/02 , C07C49/67 , C07C50/24 , C07C50/32 , C07C51/15 , C07C65/05 , C07C67/00 , C07C253/00 , C07C255/47 , C07C255/56 , C07D311/42 , C07D311/46 , C07D311/92 , C07D
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公开(公告)号：DK530074A
公开(公告)日：1975-06-09
申请号：DK530074
申请日：1974-10-10
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , CANTELLO B C C , SMITH H
IPC: C07D405/04 , C07D491/052 , C07D
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公开(公告)号：DK551481A
公开(公告)日：1982-06-14
申请号：DK551481
申请日：1981-12-11
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , SMITH H
IPC: C07C43/23 , C07D249/04 , C07D491/04 , C07D491/052 , C07D
Abstract: A compound of the formula (I): (I) wherein R1 is hydrogen or C1-6 alkyl; R2, R3 and R4 are the same or different and are chosen from hydrogen, hydroxyl, halogen, C1-4 alkyl, C1-4 alkoxy and C1-4 alkanoyl; G is H or OH; and m and n are independently 1 to 3; with the proviso that when G is OH, one of m or n is 1; is useful in the prophylaxis and treatment of diseases whose symptoms are controlled by the mediators of the allergic response, for example asthma, hay fever, rhinitis and allergic eczema.
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公开(公告)号：AU519315B2
公开(公告)日：1981-11-26
申请号：AU4113578
申请日：1978-10-27
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , SMITH H
IPC: A61K31/435 , A61P37/08 , C07D209/04 , C07D249/06 , C07D471/04 , C07D249/04 , A61K31/47
Abstract: The invention provides novel compounds of formula (I). (I) and pharmaceutically acceptable salts thereof wherein R1, R2, R3 and R4 which may be the same or different, represent hydrogen, halogen, lower alkyl, and lower alkoxy, or any adjacent two of R1 to R4 taken together represent an alkylene group containing from 3 to 5 carbon atoms or a 1,4-buta-1,3-dienylene group. The compounds are useful as anti-allergic agents.
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公开(公告)号：DK497478A
公开(公告)日：1979-05-11
申请号：DK497478
申请日：1978-11-08
Applicant: BEECHAM GROUP LTD
Inventor： BUCKLE D R , SMITH H
IPC: A61K31/41 , A61P37/08 , C07D249/16 , C07D249/22 , C07D249/24 , C07D
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