-
公开(公告)号:DK21281A
公开(公告)日:1981-07-20
申请号:DK21281
申请日:1981-01-16
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , SMITH H
IPC: C07C43/23 , C07D249/04 , C07D295/088 , C07D491/052 , C07D
Abstract: Compounds of the formula (I), or pharmaceutically acceptable salts thereof (I) wherein X is phenyl, optionally substituted by one halogen, C1-4 alkyl or C1-4 alkoxy; or pyridyl; R1 is hydrogen or C1-6 alkyl; and n is 1 to 6, pharmaceutical compositions containing them and a process for their preparation. These compounds are useful in the prophylaxis or treatment of diseases due to a histamine-mediated allergic response.
-
公开(公告)号:DK427476A
公开(公告)日:1977-03-24
申请号:DK427476
申请日:1976-09-22
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , SMITH H
IPC: C07C43/178 , C07C45/71 , C07C49/84 , C07D309/12 , C07D311/18 , C07D311/54 , C07D311/56 , C07D
-
公开(公告)号:DK235075A
公开(公告)日:1975-11-29
申请号:DK235075
申请日:1975-05-27
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , CANTELLO B C C , SMITH H
IPC: A61K31/06 , A61K31/12 , C07C45/45 , C07C45/46 , C07C46/00 , C07C46/02 , C07C49/67 , C07C49/675 , C07C49/697 , C07C49/755 , C07C50/26 , C07C50/32 , C07C50/34 , C07C67/00 , C07C201/00 , C07C205/46 , C07C205/48 , C07C
Abstract: Substituted naphthoquinones of the formula (I) and pharmaceutically acceptable salts thereof wherein R1, R2, R3 and R4 represent alkyl, aryl, alkoxy, hydroxy, hydrogen or halogen or any two of the groups R1, R2, R3 and R4 taken together complete a carbocyclic ring, have useful anti-allergy activity in mammals.
-
公开(公告)号:DK183475A
公开(公告)日:1975-11-04
申请号:DK183475
申请日:1975-04-28
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , TEDDER J M
IPC: C07C205/45 , C07C67/00 , C07C201/00 , C07D307/88 , C07D307/93 , C07C
-
公开(公告)号:DK530274A
公开(公告)日:1975-06-09
申请号:DK530274
申请日:1974-10-10
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , CANTELLO B C C , SMITH H
IPC: C07D215/22 , C07D215/26 , C07D215/38 , C07D215/40 , C07D221/04 , C07D401/04 , C07D
-
公开(公告)号:NO743655A
公开(公告)日:1975-05-05
申请号:NO743655
申请日:1974-10-10
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , CANTELLO B C C , SMITH H
IPC: C07D217/26 , C07D311/76 , C07D335/06 , C07D
CPC classification number: C07D335/06 , C07D217/26 , C07D311/76 , Y10S514/826
-
公开(公告)号:SE7412714A
公开(公告)日:1975-04-14
申请号:SE7412714
申请日:1974-10-09
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , CANTELLO B C C , SMITH H
IPC: C07D217/26 , C07D311/76 , C07D335/06 , A61K9/00
CPC classification number: C07D335/06 , C07D217/26 , C07D311/76 , Y10S514/826
-
公开(公告)号:SE7406631A
公开(公告)日:1974-11-20
申请号:SE7406631
申请日:1974-05-17
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , CANTELLO B C C SMITH H
IPC: C07D215/18 , A61K31/4704 , C07D215/22 , C07D215/26 , C07D221/10
CPC classification number: C07D215/22 , C07D215/26 , C07D221/10
-
公开(公告)号:NZ196823A
公开(公告)日:1984-10-19
申请号:NZ19682381
申请日:1981-04-15
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , SMITH H , TEDDER J M
IPC: C07D249/22 , C07D403/00 , A61K31/495
Abstract: Compounds of formula (I):wherein R is hydrogen, halogen, C 1-4 alkyl or C 1-4 alkoxy; R 1 is hydrogen or C 1-6 alkyl; and n is 1 to 6 and pharmaceutically acceptable salts thereof; pharmaceutical compositions containing them; a process for their preparation; and their use in treating allergy.
-
公开(公告)号:NZ188628A
公开(公告)日:1984-08-24
申请号:NZ18862878
申请日:1978-10-11
Applicant: BEECHAM GROUP LTD
Inventor: BUCKLE D R , SMITH H
IPC: A61K31/41 , A61P37/08 , C07D249/16 , C07D249/22 , C07D249/24 , C07D249
-
-
-
-
-
-
-
-
-