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公开(公告)号：DE69635612T2
公开(公告)日：2006-10-19
申请号：DE69635612
申请日：1996-04-30
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
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公开(公告)号：DE69635612D1
公开(公告)日：2006-01-26
申请号：DE69635612
申请日：1996-04-30
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
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公开(公告)号：AU2002230058B2
公开(公告)日：2005-11-17
申请号：AU2002230058
申请日：2002-01-29
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
IPC: C12N15/09 , A61K31/439 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/675 , A61K48/00 , A61P1/04 , A61P1/18 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P17/12 , A61P19/02 , A61P27/02 , A61P29/00 , A61P31/10 , A61P31/12 , A61P31/16 , A61P31/18 , A61P31/22 , A61P35/00 , A61P37/04 , C07D239/52 , C07D498/18 , C07H21/04 , C12Q1/68 , C12Q1/6832 , C12Q1/6839 , A61K031/535
Abstract: A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality of chiral carbon atoms, the ligands including one or more pair(s) of adjacent ligands each containing a moiety selected from the group consisting of a naturally occurring nucleobase and a nucleobase binding group, wherein moieties of the one or more pair(s) are directly linked to one another via a linker chain; building blocks for synthesizing the compound; and uses of the compound, particularly in antisense therapy.
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公开(公告)号：CA2217780A1
公开(公告)日：1998-04-30
申请号：CA2217780
申请日：1997-10-29
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
IPC: C12N15/09 , A61K31/765 , A61K48/00 , A61P31/04 , A61P31/12 , A61P35/00 , C07H21/00 , C07K1/00 , C07K19/00 , C08G65/32 , C12Q1/68 , C07C43/11 , C07C217/08 , C07D239/46 , C07D473/00 , C07F7/10 , C07F9/6512 , C07F9/6561 , C08G65/00
Abstract: A compound comprising a polyether backbone bearing a plurality of ligands that are individually bound to chiral carbon atoms located within said backbone, at least one of said ligands including a moiety selected from the group consisting of a naturally occurring nucleobase, a nucleobase binding group and a DNA intercalator; a process of synthesizing the compound, monomers to be used in thi s process and their synthesis process and processes for using the compound in biochemistry and medicine.
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公开(公告)号：DE60236144D1
公开(公告)日：2010-06-10
申请号：DE60236144
申请日：2002-01-29
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
IPC: A61K31/535 , C12N15/09 , A61K31/045 , A61K31/22 , A61K31/439 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/675 , A61K48/00 , A61P1/04 , A61P1/18 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P17/12 , A61P19/02 , A61P27/02 , A61P29/00 , A61P31/10 , A61P31/12 , A61P31/16 , A61P31/18 , A61P31/22 , A61P35/00 , A61P37/04 , C07C31/18 , C07C31/24 , C07C67/02 , C07C69/74 , C07D239/02 , C07D239/52 , C07D265/34 , C07D267/22 , C07D403/00 , C07D498/18 , C07H21/04 , C12Q1/68 , C12Q1/6832 , C12Q1/6839
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Patent Agency Ranking
公开(公告)号：AU769619B2
公开(公告)日：2004-01-29
申请号：AU6012600
申请日：2000-07-21
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
IPC: C12N15/09 , A61K31/795 , A61K48/00 , A61P31/12 , A61P35/00 , A61P43/00 , C07H19/10 , C07H19/20 , C07H21/00 , C12N5/10 , C12Q1/68 , A01N43/04 , A01N61/00 , C07H19/00 , C07H21/02 , C07H21/04
Abstract: A compound comprising a poly(ether-thioether), poly(ether-sulfoxide) or poly(ether-sulfone) backbone bearing a plurality of ligands that are individually bound to chiral carbon atoms located within the backbone, at least one of the ligands including a moiety such as a naturally occurring nucleobase, a nucleobase binding group or a DNA interchelator; a process of synthesizing the compound, monomers to be used in this process and their synthesis process and processes for using the compound in biochemistry and medicine.
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公开(公告)号：DE69718600T2
公开(公告)日：2003-11-20
申请号：DE69718600
申请日：1997-10-30
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
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公开(公告)号：DE69718600D1
公开(公告)日：2003-02-27
申请号：DE69718600
申请日：1997-10-30
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
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公开(公告)号：CA2436665A1
公开(公告)日：2002-08-08
申请号：CA2436665
申请日：2002-01-29
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
IPC: C12N15/09 , A61K31/439 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/675 , A61K48/00 , A61P1/04 , A61P1/18 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/06 , A61P17/12 , A61P19/02 , A61P27/02 , A61P29/00 , A61P31/10 , A61P31/12 , A61P31/16 , A61P31/18 , A61P31/22 , A61P35/00 , A61P37/04 , C07D239/52 , C07D498/18 , C07H21/04 , C12Q1/68 , C12Q1/6832 , C12Q1/6839 , A61K31/045 , A61K31/164 , A61K31/22 , A61K31/505 , A61K31/535 , C07C31/18 , C07C31/24 , C07C67/02 , C07C69/74 , C07D239/02 , C07D265/34 , C07D267/22 , C07D403/00
Abstract: A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality of chiral carbon atoms, the ligands including one or more pair(s) of adjacent ligands each containing a moiety selected from the group consisting of a naturally occurring nucleobas e and a nucleobase binding group, wherein moieties of the one or more pair(s) are directly linked to one another via a linker chain; building blocks for synthesizing the compound; and uses of the compound, particularly in antisen se therapy.
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公开(公告)号：AU5918396A
公开(公告)日：1996-11-21
申请号：AU5918396
申请日：1996-04-30
Applicant: BIO RAD LABORATORIES
Inventor： SEGEV DAVID
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