公开(公告)号：US20170144147A1

公开(公告)日：2017-05-25

申请号：US15425846

申请日：2017-02-06

Applicant: BacterioScan LTD.

Inventor： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

IPC: B01L3/00 ,  G01N21/51

CPC classification number: B01L3/50255 ,  B01L3/50853 ,  B01L2200/0684 ,  B01L2300/022 ,  B01L2300/043 ,  B01L2300/044 ,  B01L2300/045 ,  B01L2300/0654 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2400/0683 ,  G01N21/51 ,  G01N2021/513

Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.

公开(公告)号：US20160216204A1

公开(公告)日：2016-07-28

申请号：US15005321

申请日：2016-01-25

Applicant: BacterioScan LTD

Inventor： Dana A. Marshall ,  Dan Vadim Regelman

IPC: G01N21/51 ,  G01N21/03 ,  C12Q1/06

CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N2021/513 ,  G01N2201/0231 ,  G01N2201/0415

Abstract: An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.

Abstract translation: 仪器确定多个流体样品中细菌的浓度，并且包括壳体，可旋转平台，多个流体容器，光源，传感器和马达。 可旋转平台位于外壳内。 流体容器位于可旋转平台上。 每个流体容器保持多个流体样本中的相应的一个，并且具有输入窗口和输出窗口。 光源提供输入光束，用于传输到流体容器的输入窗口并通过相应的流体样品。 输入光束产生与细菌浓度相关联的前向散射信号。 马达旋转可旋转平台，使得输入光束顺序地通过每个流体样品。 壳体内的传感器检测从与接收输入光束的流体样品相关联的输出窗口离开的前向散射信号。

公开(公告)号：US20160160260A1

公开(公告)日：2016-06-09

申请号：US14959054

申请日：2015-12-04

Applicant: BacterioScan LTD

Inventor： Dana A. Marshall ,  Theodore S. McMinn ,  Dan Vadim Regelman

IPC: C12Q1/06 ,  G01N21/51 ,  G01N33/487

CPC classification number: C12Q1/06 ,  B01L3/50255 ,  B01L2200/0684 ,  B01L2300/022 ,  B01L2300/043 ,  B01L2300/044 ,  B01L2300/045 ,  B01L2300/0672 ,  B01L2300/0681 ,  B01L2400/0683 ,  G01N21/253 ,  G01N21/51 ,  G01N33/487 ,  G01N2021/4707 ,  G01N2201/04

Abstract: An optical measurement instrument is an integrated instrument that includes an optical cavity with a light source, a sample cuvette, and an optical sensor. The light source and sensor are on a bench that is on a translational or rotational mechanical platform such that optical beam can be moved to multiple sample containers. The instrument can be used for taking measurements of organism concentration in multiple samples as a production tool for microbiology. Preferably, the instrument holds multiple, individually-loaded, independent fluid samples and determines bacteria concentration via a forward-scattering signal. The instrument can incorporate onboard incubation to promote bacterial growth in the samples during the test. In another aspect, the instrument can be a part of a network for medical diagnostic testing data where data is stored in a manner that is inherently untainted by patient identifiable information.

Abstract translation: 光学测量仪器是一种集成的仪器，其包括具有光源的光学腔，样品比色皿和光学传感器。 光源和传感器位于平移或旋转机械平台上的工作台上，使得光束可以移动到多个样品容器。 该仪器可用于测量多个样品中的生物体浓度，作为微生物学的生产工具。 优选地，仪器保持多个单独加载的独立流体样品，并通过前向散射信号确定细菌浓度。 该仪器可以包含板内孵化，以在测试过程中促进样品中的细菌生长。 在另一方面，该仪器可以是用于医疗诊断测试数据的网络的一部分，其中以由患者可识别信息固有地保持的方式存储数据。