-
Patent Agency Ranking11.发明公开
公开(公告)号：EP2381116A1
公开(公告)日：2011-10-26
申请号：EP11161890.6
申请日：2001-11-16
Applicant: California Institute of Technology
Inventor： Quake, Stephen R. , Unger, Marc Alexander , Chou, Hou-Pu , Thorsen, Tod A.
CPC classification number: G01N33/00 , B01D57/02 , B01D61/18 , B01D61/28 , B01D63/081 , B01D63/088 , B01D2313/08 , B01D2313/90 , B01F5/0646 , B01F5/0647 , B01F7/00 , B01F11/0071 , B01F13/0059 , B01F13/1013 , B01F13/1022 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L3/502761 , B01L2200/0631 , B01L2200/10 , B01L2300/0627 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2300/123 , B01L2300/1822 , B01L2300/1827 , B01L2400/0415 , B01L2400/0481 , B01L2400/0487 , B01L2400/0633 , B01L2400/0655 , B01L2400/082 , C12M23/16 , C12M41/46 , F04B43/043 , F16K99/0001 , F16K99/0009 , F16K99/0015 , F16K99/0046 , F16K99/0048 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , G01N15/06 , G01N27/44743 , G01N27/44791 , G01N33/5005 , G01N33/5008 , G01N33/56966 , Y10T436/11 , Y10T436/117497 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
Abstract: The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.
Abstract translation: 本发明提供了使用相同的微流体装置和方法。 特别地，本发明的微流体装置是在进行各种分析和高通量筛选是有用的。 本发明的微流体装置包括弹性部件和包括主流动通道; 分支流动通道的多元性; 控制信道与多个; 和阀门多数。 优选地，每个所述阀包括控制通道中的一个，并在弹性链段所做的是可偏转或从在其响应所述阀操作以施加到控制信道致动力的主要或分支流动通道可缩回的。
-
公开(公告)号：EP2309130A2
公开(公告)日：2011-04-13
申请号：EP10180441.7
申请日：2000-06-27
Applicant: California Institute of Technology
Inventor： Unger, Marc A. , Scherer, Axel , Quake, Stephen R. , Chou, Hou-Pu , Thorsen, Todd A.
CPC classification number: B29C51/00 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L2300/0861 , B01L2300/0887 , B01L2300/123 , B01L2400/046 , B01L2400/0481 , B01L2400/0655 , B33Y80/00 , B81B5/00 , B81B2201/036 , B81B2201/054 , B81C1/00119 , B81C2201/019 , B81C2201/034 , C12Q1/6874 , F04B43/043 , F15C1/06 , F15C5/00 , F16K11/20 , F16K13/00 , F16K31/126 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0048 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0076 , F16K2099/0078 , F16K2099/008 , F16K2099/0094 , Y10T137/0491 , Y10T137/0497 , Y10T137/2224 , Y10T137/87249 , Y10T156/10 , Y10T428/24479 , Y10T428/24744 , C12Q2535/125
Abstract: A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer, bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.
Abstract translation: 一种制造弹性体结构的方法，包括：在第一微加工模具的顶部上形成第一弹性体层，所述第一微加工模具具有形成沿所述第一弹性体层的底表面延伸的第一凹槽的第一凸起突起; 在第二微加工模具的顶部上形成第二弹性体层，所述第二微加工模具具有第二凸起突起，所述第二凸起突起形成沿着所述第二弹性体层的底表面延伸的第二凹槽，将所述第二弹性体层的底表面接合到顶部 第一弹性体层的表面，使得控制通道在第一和第二弹性体层之间的第二凹部中形成; 以及将所述第一弹性体层定位在平面基底的顶部上，使得在所述第一弹性体层和所述平面基底之间的所述第一凹部中形成流动通道。
-
公开(公告)号：EP1195523B1
公开(公告)日：2005-03-02
申请号：EP01128819.8
申请日：2000-06-27
Applicant: California Institute of Technology
Inventor： Unger, Marc A. , Scherer, Axel , Quake, Stephen R. , Chou, Hou-Pu , Thorsen, Todd A.
CPC classification number: F04B43/043 , F15C5/00
-
公开(公告)号：EP1195523A3
公开(公告)日：2003-01-08
申请号：EP01128819.8
申请日：2000-06-27
Applicant: California Institute of Technology
Inventor： Unger, Marc A. , Scherer, Axel , Quake, Stephen R. , Chou, Hou-Pu , Thorsen, Todd A.
CPC classification number: F04B43/043 , F15C5/00
Abstract: A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.
-
15.发明授权MICROFABRICATED ELASTOMERIC VALVE AND PUMP SYSTEMS 有权ELASTOMERISCHE MIKROPUMPEN-在MIKROVENTILSYSTEME
公开(公告)号：EP1065378B1
公开(公告)日：2002-04-03
申请号：EP00305389.9
申请日：2000-06-27
Applicant: California Institute of Technology
Inventor： Unger, Marc A. , Chou, Hou-Pu , Thorsen, Todd A. , Scherer, Axel , Quake, Stephen R.
CPC classification number: B29C51/00 , B01L3/502707 , B01L3/50273 , B01L3/502738 , B01L2300/0861 , B01L2300/0887 , B01L2300/123 , B01L2400/046 , B01L2400/0481 , B01L2400/0655 , B33Y80/00 , B81B5/00 , B81B2201/036 , B81B2201/054 , B81C1/00119 , B81C2201/019 , B81C2201/034 , C12Q1/6874 , F04B43/043 , F15C1/06 , F15C5/00 , F16K11/20 , F16K13/00 , F16K31/126 , F16K99/0001 , F16K99/0015 , F16K99/0046 , F16K99/0048 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/0076 , F16K2099/0078 , F16K2099/008 , F16K2099/0094 , Y10T137/0491 , Y10T137/0497 , Y10T137/2224 , Y10T137/87249 , Y10T156/10 , Y10T428/24479 , Y10T428/24744 , C12Q2535/125
-
-
-
-
Search Results
15
records
(took 0.038 seconds)
