公开(公告)号：EP3196300A1

公开(公告)日：2017-07-26

申请号：EP15837358.9

申请日：2015-09-04

Applicant: Cj Cheiljedang Corporation

Inventor： HUH, Lan ,  LEE, Kwang Ho ,  KIM, Hyung Joon ,  MOON, Jun Ok ,  RYU, Song-Gi

IPC: C12N9/12 ,  C12N15/54 ,  C12R1/15 ,  C12P13/08

CPC classification number: C07K14/34 ,  C12N9/12 ,  C12P13/08 ,  C12R1/15 ,  C12Y207/07006

Abstract: The present disclosure relates to a novel modified RNA polymerase sigma factor A (SigA) polypeptide; a polynucleotide encoding the same; a microorganism containing the polypeptide; and a method for producing L-lysine using the microorganism.

Abstract translation: 本公开涉及新的修饰的RNA聚合酶西格玛因子A（SigA）多肽; 编码它的多核苷酸; 含有该多肽的微生物; 以及使用该微生物生产L-赖氨酸的方法。

公开(公告)号：EP3147351A1

公开(公告)日：2017-03-29

申请号：EP15795904.0

申请日：2015-04-14

Applicant: CJ Cheiljedang Corporation

Inventor： JANG, Juno ,  PARK, Hye Min ,  LEE, Kwang Ho ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12N1/20 ,  C12P13/08

CPC classification number: C12N1/20 ,  C07K14/245 ,  C12P13/04 ,  C12P13/08 ,  C12P13/227

Abstract: The present application relates to a recombinant microorganism having an improved intracellular energy level and a method for producing L-amino acid using the microorganism.

Abstract translation: 本申请涉及具有提高的细胞内能量水平的重组微生物和使用该微生物生产L-氨基酸的方法。

公开(公告)号：EP3336191B1

公开(公告)日：2019-08-21

申请号：EP16792968.6

申请日：2016-05-10

Applicant: CJ Cheiljedang Corporation

Inventor： PARK, Hye Min ,  LEE, Baek Seok ,  LEE, Seok Myung ,  KIM, Kyungrim ,  LEE, Kwang Ho ,  CHEONG, Ki Yong ,  LEE, Keun Cheol ,  HONG, Hyeongpyo

IPC: C12N15/70 ,  C12P13/22

公开(公告)号：EP3404101A3

公开(公告)日：2018-12-26

申请号：EP18182250.3

申请日：2012-12-21

Applicant: Cj Cheiljedang Corporation

Inventor： LEE, Kwang Ho ,  LIM, Sang Jo ,  MOON, Jun Ok ,  JANG, Jae Woo ,  PARK, Su Jin ,  PARK, Sang Hee

IPC: C12N15/52 ,  C12N15/63 ,  C12N15/74 ,  C12P13/08

CPC classification number: C12P13/08 ,  C12N9/1022 ,  C12N9/1217 ,  C12N9/93 ,  C12N15/52 ,  C12N15/63 ,  C12N15/74 ,  C12Y202/01001 ,  C12Y207/02004 ,  C12Y604/01001 ,  Y02P20/52

Abstract: The present invention relates to a modified polynucleotide encoding aspartate kinase (EC:2.7.2.4; hereinafter, referred to as LysC), transketolase (EC:2.2.1.1; hereinafter, referred to as Tkt) or pyruvate carboxylase (EC:6.4.1.1; hereinafter, referred to as Pyc), in which the initiation codon is substituted with ATG, a vector including the same, a microorganism transformed with the vector, and a method for producing L-lysine using the same.

公开(公告)号：EP3366776A1

公开(公告)日：2018-08-29

申请号：EP16857824.3

申请日：2016-10-21

Applicant: CJ Cheiljedang Corporation

Inventor： SEO, Chang Il ,  PARK, Hye Min ,  LEE, Kwang Ho ,  PARK, Sang Min ,  KIM, Kyung Rim ,  CHEONG, Ki Yong

IPC: C12N15/70 ,  C12N15/77 ,  C12N9/10 ,  C12N9/88

CPC classification number: C12N9/10 ,  C12N9/88 ,  C12N15/70 ,  C12N15/77

Abstract: The present disclosure relates to a recombinant microorganism producing threonine, and a method for producing L-threonine using the same.

公开(公告)号：EP3064569A1

公开(公告)日：2016-09-07

申请号：EP14858611.8

申请日：2014-09-25

Applicant: CJ Cheiljedang Corporation

Inventor： PARK, Sang Hee ,  MOON, Jun Ok ,  BAE, Hyun Won ,  LEE, Kwang Ho

IPC: C12N1/21 ,  C12P13/08

CPC classification number: C12P13/08 ,  C12N1/20

Abstract: Provided are a microorganism of Corynebacterium sp., which is modified to over-express a NCg10862 gene of Corynebacterium glutamicum, so as to have enhanced L-lysine producibility, and a method of producing L-lysine by using the microorganism.

Abstract translation: 本发明提供了棒状杆菌属的微生物。，所有这些被修饰以过表达谷氨酸棒杆菌NCg10862的基因，从而具有增强的L-赖氨酸生产性，并且通过使用该微生物生产L-赖氨酸的方法。

公开(公告)号：EP3015546A1

公开(公告)日：2016-05-04

申请号：EP14817261.2

申请日：2014-06-24

Applicant: CJ Cheiljedang Corporation

Inventor： PARK, Sang Hee ,  MOON, Jun Ok ,  LEE, Kwang Ho

IPC: C12N9/10 ,  C12N15/54 ,  C12N15/63 ,  C12N15/77

Abstract: Provided are a beta prime subunit mutant of RNA polymerase, a microorganism of the Corynebacterium genus including a polynucleotide coding the same, and a method for producing L-lysine by culturing the same.

Abstract translation: 本发明提供的β'亚基突变体的RNA聚合酶，棒杆菌属，包括多核苷酸编码相同的微生物，以及用于通过培养相同的生产L-赖氨酸的方法。

公开(公告)号：EP2803722A2

公开(公告)日：2014-11-19

申请号：EP13736186.1

申请日：2013-01-10

Applicant: Cj Cheiljedang Corporation

Inventor： RAH, So Yeon ,  HUH, Lan ,  KIM, Chang Gyeom ,  LEE, Kwang Ho ,  MOON, Jun Ok ,  LEE, Kyung Han ,  SUNG, Jin Seok ,  KIM, Hyung Joon

IPC: C12N1/21 ,  C12N15/52 ,  C12N15/74 ,  C12P13/08

CPC classification number: C12P13/08 ,  C12N9/1205 ,  C12N9/92 ,  C12Y207/01017 ,  C12Y503/01005 ,  Y02P20/52

Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.

公开(公告)号：EP2665809A2

公开(公告)日：2013-11-27

申请号：EP12736463.6

申请日：2012-01-18

Applicant: CJ Cheiljedang Corporation

Inventor： LEE, Kwang Ho ,  LEE, Keun Chul ,  LEE, Seok Myung ,  HWANG, Young Bin

IPC: C12N1/21 ,  C12N15/54 ,  C12N15/70 ,  C12N15/69 ,  C12P13/08

CPC classification number: C12N15/70 ,  C07K14/245 ,  C12N9/1007 ,  C12N9/1205 ,  C12P13/04 ,  C12P13/08 ,  C12P13/227 ,  C12Y201/01 ,  C12Y207/01023

Abstract: A microorganism of the genus Escherichia having enhanced L-amino acid productivity, wherein the microorganism is transformed to have an enhanced NAD kinase activity and an inactivated activity of an enzyme having an amino acid sequence of SEQ ID NO: 2 encoded by tehB gene and a method for producing L-amino acids using the microorganism of the genus Escherichia.

公开(公告)号：EP3147351B1

公开(公告)日：2019-08-28

申请号：EP15795904.0

申请日：2015-04-14

Applicant: CJ Cheiljedang Corporation

Inventor： JANG, Juno ,  PARK, Hye Min ,  LEE, Kwang Ho ,  LEE, Keun Cheol ,  HONG, Hyeong Pyo

IPC: C12P13/08 ,  C12P13/22