DESENSITIZING DENTIFRICE EXHIBITING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE
    11.
    发明申请
    DESENSITIZING DENTIFRICE EXHIBITING DENTAL TISSUE ANTIBACTERIAL AGENT UPTAKE 审中-公开
    脱皮剂展示牙科组织抗菌药物摄取

    公开(公告)号:WO2010114538A1

    公开(公告)日:2010-10-07

    申请号:PCT/US2009/039194

    申请日:2009-04-01

    Abstract: An oral composition exhibiting increased uptake by dental tissue of antibacterial compounds contained therein and eliminating or substantially reducing the discomfort and pain associated with dentinal hypersensitivity. The composition includes an orally acceptable vehicle for such composition, an effective therapeutic amount of an antibacterial compound, a mixture of anionic surfactant and amphoteric surfactant, the mixture having 0.1 wt. % to 2.0 wt. % anionic surfactant and 0.8 wt. % to 2.0 wt. % amphoteric surfactant, and a potassium ion releasable compound.

    Abstract translation: 一种口服组合物,其表现出牙齿组织对其中所含的抗菌化合物的吸收增加,并消除或显着降低与牙质过敏有关的不适和疼痛。 该组合物包括用于这种组合物的口服可接受的载体,有效治疗量的抗菌化合物,阴离子表面活性剂和两性表面活性剂的混合物,该混合物具有0.1wt。 %〜2.0重量% %阴离子表面活性剂和0.8wt。 %〜2.0重量% %两性表面活性剂和一种钾离子可释放的化合物。

    ANTIBACTERIAL 3',5-DISUBSTITUTED 2,4'-DIHYDROXYBIPHENYL COMPOUNDS, DERIVATIVES AND RELATED METHODS
    13.
    发明申请
    ANTIBACTERIAL 3',5-DISUBSTITUTED 2,4'-DIHYDROXYBIPHENYL COMPOUNDS, DERIVATIVES AND RELATED METHODS 审中-公开
    抗真菌3',5-取代的2,4'-二羟基二苯基化合物,衍生物及相关方法

    公开(公告)号:WO2006101818A1

    公开(公告)日:2006-09-28

    申请号:PCT/US2006/009046

    申请日:2006-03-14

    CPC classification number: A61K9/0056 A61K8/347 A61K31/05 A61Q11/00

    Abstract: The invention provides an antiplaque oral composition containing an orally acceptable carrier and an antibacterial effective amount of compound (I). In the structure, R 1 and R 2 are independently a hydrogen atom or a lower C 1-4 alkyl group and R 3 and R 4 are independently an alkenyl or alkyl group having from 1 to 20 carbon atoms, with the proviso that R 3 and R 4 are not both 2-propenyl or n-propyl when R 1 and R 2 are both hydrogen atoms. Also included are oral compositions containing the compound (I).

    Abstract translation: 本发明提供了含有口服可接受的载体和抗菌有效量的化合物(I)的抗牙龈口服组合物。 在结构中,R 1和R 2独立地是氢原子或低级C 1-4烷基,R 3 R 4和R 4独立地是具有1至20个碳原子的烯基或烷基,条件是R 3和R 4, 当R 1和R 2都是氢原子时,SUP>不是2-丙烯基或正丙基。 还包括含有化合物(I)的口服组合物。

    IMPROVED DENTAL WHITENING METHOD
    14.
    发明申请
    IMPROVED DENTAL WHITENING METHOD 审中-公开
    改进的牙齿白化方法

    公开(公告)号:WO2005094768A1

    公开(公告)日:2005-10-13

    申请号:PCT/US2005/010421

    申请日:2005-03-29

    CPC classification number: A61K8/22 A61K2800/88 A61Q11/00

    Abstract: A method for whitening a dental surface comprises nonsimultaneously applying a whitening composition to the surface, the whitening composition comprising at least one orally acceptable peroxy compound, and directing a volume of up to about 2.5 ml of an atomized activating composition on to the surface, wherein the activating composition comprises, in the volume so directed, a peroxy compound activating effective amount of at least one orally acceptable basifying agent, and wherein applying the whitening composition and directing the activating composition are separated by an interval not greater than a peroxy compound activating effective interval. The atomized composition can be directed on to the dental surface before or after application of the whitening composition.

    Abstract translation: 美白牙齿表面的方法包括将美白组合物同时施用于表面,美白组合物包含至少一种口服可接受的过氧化合物,并将一定体积的至多约2.5ml雾化的活化组合物引导至表面,其中 活化组合物包括在如此定向的体积中活化有效量的至少一种口服可接受的碱化剂的过氧化合物,并且其中施用所述增白组合物并引导所述活化组合物以不大于过氧化合物活化的有效间隔 间隔。 雾化组合物可以在施用美白组合物之前或之后被引导到牙齿表面。

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