公开(公告)号：JPH11147854A

公开(公告)日：1999-06-02

申请号：JP31567297

申请日：1997-11-17

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO

IPC: B01J31/24 ,  C07B61/00 ,  C07C67/38 ,  C07C69/54

Abstract: PROBLEM TO BE SOLVED: To provide a carbonylation method for an ethylene- or acetylene-based hydrocarbon which is capable of suppressing metallization of a metal complex occurring during the carbonylation in the presence of a catalytic system containing a group VIII metal complex. SOLUTION: This carbonylation method for an ethylene- or acetylene-based hydrocarbon includes a process to react, in the presence of a catalytic system containing (1) a supply source of a group VIII metal atom or its ion, (2) an organophosphine compound and (3) an acid, (a) an ethylene- or acetylene-based hydrocarbon compound having one or more unsaturated bonds between carbons, with (b) carbon monoxide and (c) at least one nucleophilic compound selected from the group consisting of water, alcohols and carboxylic acids, wherein the reaction process is advanced by maintaining the concentration of the carbon monoxide in the reaction liquor to be 0.05-0.3 mol/L.

公开(公告)号：JPH10114703A

公开(公告)日：1998-05-06

申请号：JP27257396

申请日：1996-10-15

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO ,  HAN RITSUZUI

IPC: B01J31/24 ,  C07B61/00 ,  C07C51/145 ,  C07C57/04 ,  C07C67/38 ,  C07C69/533 ,  C07C69/54

Abstract: PROBLEM TO BE SOLVED: To carry out carbonylation of an acetylene-type or allene-type unsaturated compound while stably keeping high conversion over a 1.ong period by reacting the unsaturated compound with carbon monoxide in the presence of a specific catal-ysl:: while keeping the conversion of the unsaturated corrpound within a specific range. SOLUTION: A carbonylation catalyst is produced e.g. by compounding l mol of a group Vlll metal source (e.g. tetrakistriphenylphosphineplatinum), 2-100 mol of a ligand (e.jg. triphenylphosphine) and 2-400 mol of an acid (e.g. methacrylic acid). An acetylene-type or allene-type unsaturated compound (e.g. propyne) is carbonylated with carbon monoxide at 10-250'C under atmospheric pressure to 150 atm in the presence of the catalyst while keeping the conversion of the unsaturated compound to ?9O%, preferdly S95%.

公开(公告)号：JPH08245495A

公开(公告)日：1996-09-24

申请号：JP7821195

申请日：1995-03-08

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO

IPC: C07C51/06 ,  C07B61/00 ,  C07C51/08 ,  C07C53/124 ,  C07C59/08

Abstract: PURPOSE: To produce a carboxylic acid while effectively utilizing a salt and ammonia which are components of a catalyst formed as by-products by hydrolyzing a nitrile or an amide compound. CONSTITUTION: A nitrile or an amide compound is hydrolyzed with an acidic catalyst such as an inorganic acid and an ammonium salt of the acidic catalyst formed as a by-product is electrodialyzed to produce an acid and ammonia. The resultant acid is then used as a catalyst in the step for hydrolyzing the nitrile or amide compound and the produced ammonia is used as a nitrogen source in a step for producing the nitrile or amide compound. When the compound is hydrolyzed with a basic catalyst such as an alkali metallic hydroxide, the salt of the carboxylic acid with the base formed as a by-product is electrodialyzed to produce the carboxylic acid and base. The resultant base is then reutilized as a catalyst in a step for hydrolyzing the nitrile compound. The ammonia produced by the electrodialysis is reutilized as the nitrogen source in the step for producing the nitrile or amide compound. The electrodialysis can be carried out with an ion exchange membrane constituted of at least one membrane of a bipolar, a cation exchange and an anion exchange membranes.

公开(公告)号：JPH01203377A

公开(公告)日：1989-08-16

申请号：JP2573788

申请日：1988-02-08

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO

IPC: C07D317/20 ,  C07D319/12

Abstract: PURPOSE:To obtain dihydroxyacetone dimer which is used as a starting substance for medicines through a simple process by keeping crystals of dihydroxyacetone monomer or a mixture thereof with dimer crystals in a certain temperature range near room temperature. CONSTITUTION:The crystals of dihydroxyacetone monomer or a mixture thereof with dimer crystals are kept at 0-40 deg.C to convert the monomer crystals into the dimer crystals completely within at least 1,000hr. The atmosphere on its storage may be air or other inert gases, but the storage in high humidity is not desired.

公开(公告)号：JPH01203348A

公开(公告)日：1989-08-16

申请号：JP2573988

申请日：1988-02-08

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO ,  FUKUNISHI KUNIO

IPC: C12P7/18 ,  C07C45/00 ,  C07C45/81 ,  C07C49/17 ,  C07C67/00

Abstract: PURPOSE:To efficiently and readily obtain the present compound which is a raw material for medicines, by controlling the time up to start of crystallization after concentration and obtaining a crystallization liquor excellent in filterability in concentrating an aqueous solution of dihydroxyacetone, adding a solvent to the concentrated solution and carrying out crystallization. CONSTITUTION:An aqueous solution of dihydroxyacetone is concentrated and a solvent is then added after the concentration to carry out crystallization. In the process, dehydration and concentration are performed until the moisture content in the concentrated solution attains =90wt.%. After the concentration, a solvent is then added to carry out crystallization so that the time up to start of crystallization may not exceed 50hr. Thereby, the aimed compound is obtained. A lower alcohol, such as isopropanol, acetone, etc., are used as the solvent. The amount of the solvent used is preferably 0.3-2.0pts.wt. based on 1pt.wt. dihydroxyacetone. The temperature for carrying out the crystallization is optimally within the range of 0-30 deg.C.

公开(公告)号：JPS63162044A

公开(公告)日：1988-07-05

申请号：JP31444286

申请日：1986-12-25

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO ,  KOJIMA HIDETAKA

IPC: B01J38/00 ,  B01J23/94 ,  B01J23/96 ,  C07B31/00 ,  C07B63/00 ,  C07C51/00 ,  C07C51/12 ,  C07C51/47 ,  C07C53/08 ,  C07C57/30 ,  C07C67/00

Abstract: PURPOSE:To efficiently recover transition metal with a simple method, by adsorbing and separating trace transition metal which remains in a reaction product obtained by using a transition metallic catalyst by means of an adsorbent. CONSTITUTION:In a chemical reaction process wherein a transition metallic catalyst such as Rh, Co and Pd is used, the transition metal incorporated in a reaction product is ordinarily recovered at about 90-99% of the used catalyst by flushing or extraction. Further the remaining trace catalyst (transition metal), namely the remaining catalyst not more than 1-10% of the used catalyst is ordinarily adsorbed and separated by using an adsorbent such as activated carbon and silica gel and recovered at nearly 100% efficiency. In this case, in order to adsorb the transition metal incorporated in the reaction product to the adsorbent, the reaction product is intactly brought into contact with the adsorbent or brought into contact therewith after diluting it with a solvent.

公开(公告)号：JP2001002620A

公开(公告)日：2001-01-09

申请号：JP17509499

申请日：1999-06-22

Applicant: DAICEL CHEM

Inventor： MATSUOKA KAZUYUKI ,  TERADA MASAHIKO ,  KAWABE MASATO

IPC: B01J27/06 ,  C07B61/00 ,  C07C51/265 ,  C07C63/313

Abstract: PROBLEM TO BE SOLVED: To reduce the lowering of a catalytic activities because of the catalyst becoming insoluble during the reaction, and further to omit a complex step for making the aromatic polycarboxylic acid free by suppressing the formation of a compound composed of the produced aromatic polycarboxylic acid and the catalyst. SOLUTION: This method for producing an aromatic polycarboxylic acid by oxidizing an aromatic polyalkyl compound comprises using a heavy metal and bromine as a catalyst, oxidizing the aromatic polyalkyl in a mixed solvent of 3-50 wt.% lower fatty acid and water to suppress the lowering of the activities of the catalyst and formation of an insoluble compound by the reaction of the aromatic polycarboxylic acid with the catalyst.

公开(公告)号：JPH11147002A

公开(公告)日：1999-06-02

申请号：JP31566997

申请日：1997-11-17

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO ,  SUGAWARA MICHIHIRO

IPC: B01D15/00 ,  B01J20/02 ,  B01J20/18 ,  B01J31/22 ,  B01J31/24 ,  B01J38/00

Abstract: PROBLEM TO BE SOLVED: To provide a method for recovering efficiently a complex compd. of a metal of Group VIII in the periodic table. SOLUTION: An org. solvent (1) selected from a group consisting of aliph. hydrocarbons, alicyclic hydrocarbons and combinations thereof is compounded with a liq. to be treated contg. a complex compd. of a metal of Group VIII in element periodic table and the complex compd. of a metal of the Group VIII in the element periodic table is adsorbed with a polar adsorbent by bringing the mixed liq. into contact with the polar adsorbent. Then, an eluent (2) with higher polarity than the org. solvent is used to elute the complex compd. of a metal of Group VIII in the element periodic table adsorbed with the polar adsorbent.

公开(公告)号：JPH1110009A

公开(公告)日：1999-01-19

申请号：JP16240897

申请日：1997-06-19

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO ,  SATO YASUSHI

IPC: B01J31/28 ,  B01J31/40 ,  B01J38/00 ,  C07B61/00 ,  C07C51/14 ,  C07C51/48 ,  C07C57/04 ,  C07C67/38 ,  C07C67/58 ,  C07C69/54

Abstract: PROBLEM TO BE SOLVED: To efficiently separate and recover catalytic components from a carbonylation reaction product. SOLUTION: The carbonylation reaction product containing the catalyst consisting of a group VIII metal source A in periodic Table such as a platinum compound and an organic phosphorus such as triphenyl phosphine, arsenic or an antimony compound B is extracted by at least one kind of a solvent D selected from an aliphatic hydrocarbon such as hexane, an alicyclic hydrocarbon such as cyclohexane and the like in the coexistence of an α,β-unsaturated carbonic acid C and the catalyst is recovered from the raffinate.

公开(公告)号：JPH0194938A

公开(公告)日：1989-04-13

申请号：JP25000787

申请日：1987-10-05

Applicant: DAICEL CHEM

Inventor： KAWABE MASATO ,  HARANO YOSHIYUKI

IPC: B01J4/00 ,  B01J4/04

Abstract: PURPOSE:To form easily a flow with a uniform distribution of velocity, by installing a distribution plate which causes a large pressure loss in a fluid passage to eliminate the presence of dead zone when fluids are diffused from a fluid inlet into a passage having a larger sectional area. CONSTITUTION:A distribution plate 2 is disposed in a fluid passage in a diffuser 1 so that the pressure drop caused by the fluid when it passes through the distribution plate 2 is much larger than that caused by the fluid when it flows radially outwardly through the space 3 between the plate 2 and a fluid inlet 5. The distribution plate 2 is made of porous plate of sintered metal etc., having pores with a diameter of 3-7mum, while the depth of the space 3 is made 5mum-1cm to make the pressure loss within the space 3 sufficiently small. As a result, on both sides of the distribution plate 2, no change in concentration of the fluid occurs and the fluid does not separate from said plate, causing a good piston flow of the fluid thereafter.