FAST STARTUP ION CHROMATOGRAPHY SYSTEM AND METHODS

    公开(公告)号:US20210389289A1

    公开(公告)日:2021-12-16

    申请号:US17459757

    申请日:2021-08-27

    Abstract: Systems and methods for inhibiting translocation of ions across ion exchange barriers include an eluent generator having an ion source reservoir with a first electrode, an eluent generation chamber with a second electrode, an ion exchange barrier disposed therebetween, and means for reversing the polarity of a voltage or current applied across the first and second electrodes. A first polarity voltage or current applied across the electrodes generates an electric field that promotes translocation of eluent counter ions from the reservoir across the barrier, where the counter ions combine with eluent ions electrolytically generated in the chamber. By reversing the polarity of the voltage or current across the electrodes, the resulting electric field inhibits translocation of counter ions across the barrier from the reservoir into the chamber. Reverse voltage or current bias reduces counter ion concentration in the resting chamber to prevent exhaustion of ion suppressor capacity during start up.

    GAS-LESS ELUENT GENERATOR
    14.
    发明公开

    公开(公告)号:US20240209517A1

    公开(公告)日:2024-06-27

    申请号:US18146485

    申请日:2022-12-27

    CPC classification number: C25B1/02 C25B1/22 C25B11/042 G01N30/62 G01N2030/027

    Abstract: An eluent generation module includes an electrolytic gas generator and an electrolytic eluent generator. The electrolytic gas generator includes a generation chamber having an inlet and an outlet; an outlet electrode within the generation chamber; a first ion exchange connector; a bulk solvent chamber separated from the generation chamber by the ion exchange connector; and a bulk solvent chamber electrode within the bulk solvent chamber. The electrolytic eluent generator includes an electrolyte chamber containing an aqueous electrolyte solution; an electrolyte chamber electrode within the electrolyte chamber; a second ion exchange connector; an eluent generation chamber separated from the electrolyte chamber by the second ion exchange connector; and an eluent generation chamber electrode.

    DISPOSABLE THIN-FILM PLATINUM HYDROGEN REFERENCE ELECTRODE

    公开(公告)号:US20240201146A1

    公开(公告)日:2024-06-20

    申请号:US18068246

    申请日:2022-12-19

    CPC classification number: G01N30/64 G01N2030/027

    Abstract: The present invention relates to, in general, a disposable electrically insulating substrate surface comprising a platinum hydrogen reference electrode system structure, the use of such a substrate in a flow-through electrochemical cell assembly and methods of manufacturing said substrate. For example, in some embodiments, a disposable electrically insulating substrate surface comprising a platinum hydrogen reference electrode system structure, wherein the platinum hydrogen reference electrode system comprises an electrically conductive and electrochemically active platinum hydrogen reference electrode system region bound as a layer, directly or indirectly, to said substrate surface.

    MONITORING AND MITIGATING SUPPRESSOR FAILURE
    16.
    发明公开

    公开(公告)号:US20230341361A1

    公开(公告)日:2023-10-26

    申请号:US18186391

    申请日:2023-03-20

    CPC classification number: G01N30/96 G01N2030/965

    Abstract: A suppressor comprising one or more channels, a flow path for each of the channels, and one or more measurement probes positioned in the flow path is described. Each channel includes an inlet and an outlet. Each flow path includes an upstream path to the inlet, a channel stream path through the channel and connecting the inlet to the outlet, and a downstream path from the outlet. A system including the suppressor as well as methods implementing the suppressor are also described.

    Fast startup ion chromatography system and methods

    公开(公告)号:US11105782B2

    公开(公告)日:2021-08-31

    申请号:US15729480

    申请日:2017-10-10

    Abstract: Systems and methods for inhibiting translocation of ions across ion exchange barriers include an eluent generator having an ion source reservoir with a first electrode, an eluent generation chamber with a second electrode, an ion exchange barrier disposed therebetween, and means for reversing the polarity of a voltage or current applied across the first and second electrodes. A first polarity voltage or current applied across the electrodes generates an electric field that promotes translocation of eluent counter ions from the reservoir across the barrier, where the counter ions combine with eluent ions electrolytically generated in the chamber. By reversing the polarity of the voltage or current across the electrodes, the resulting electric field inhibits translocation of counter ions across the barrier from the reservoir into the chamber. Reverse voltage or current bias reduces counter ion concentration in the resting chamber to prevent exhaustion of ion suppressor capacity during start up.

Patent Agency Ranking