-
公开(公告)号:ES2403560T3
公开(公告)日:2013-05-20
申请号:ES02786834
申请日:2002-11-27
Applicant: FLUIDIGM CORP
Inventor: UNGER MARC A , MANGER IAN DAVID , LUCERO MICHAEL , YI YONG , MIYASHITA-LIN EMILY , WIENECKE ANJA , FACER GEOFFREY
IPC: B01L3/00 , B01F13/00 , G01N33/53 , C12M1/00 , C12Q1/25 , C12Q1/68 , C40B40/02 , C40B50/06 , C40B60/12 , C40B60/14 , F04B43/02 , G01N1/00 , G01N1/28 , G01N27/447 , G01N35/00 , G01N37/00
Abstract: Un dispositivo microfluídico (200), que comprende componentes elastoméricos, y que tiene un canal de flujo (204, 702), en el que dicho canal de flujo tiene una pluralidad de canales de flujo ciego (206) que se abren hacia el interior y están en comunicación de fluidos con el canal de flujo, caracterizándose cada canal de flujo ciego por tener una parte de apertura, una parte de canal, y una parte final, y en el que una región del final de cada canal de flujo ciego define un sitio de reacción (208, 706), en el que cada canal de flujo ciego está asociado con una válvula (212) que cuando se cierra aísla el sitio de reacción del canal de flujo, y caracterizado por que las válvulas asociadas con cada una de la pluralidad de canales de flujo ciego en comunicación de fluidos con el canal de flujo están bajo el control de un canal de control común (210, 712) y se cierran o abren de forma coordinada.
-
公开(公告)号:CA2807564A1
公开(公告)日:2004-10-21
申请号:CA2807564
申请日:2004-04-05
Applicant: FLUIDIGM CORP
Inventor: MCBRIDE LINCOLN , LUCERO MICHAEL , UNGER MARC , NASSEF HANY RAMEZ , FACER GEOFFREY
-
公开(公告)号:CA2521171A1
公开(公告)日:2004-10-21
申请号:CA2521171
申请日:2004-04-05
Applicant: FLUIDIGM CORP
Inventor: NASSEF HANY RAMEZ , UNGER MARC , FACER GEOFFREY , MCBRIDE LINCOLN , LUCERO MICHAEL
Abstract: A variety of elastomeric-based microfluidic devices and methods for using an d manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which reagent s have been previously deposited during manufacture. The reagents become suspended once sample is introduced into the reaction site. The devices can be utilized with a variety of heating devices and thus can be used in a variety of analyses requiring temperature control, including thermocycling applications such as nucleic acid amplification reactions, genotyping and ge ne expression analyses.
-
公开(公告)号:AU2004228678A1
公开(公告)日:2004-10-21
申请号:AU2004228678
申请日:2004-04-05
Applicant: FLUIDIGM CORP
Inventor: UNGER MARC , MCBRIDE LINCOLN , FACER GEOFFREY , LUCERO MICHAEL , NASSEF HANY RAMEZ
Abstract: A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which reagents have been previously deposited during manufacture. The reagents become suspended once sample is introduced into the reaction site. The devices can be utilized with a variety of heating devices and thus can be used in a variety of analyses requiring temperature control, including thermocycling applications such as nucleic acid amplification reactions, genotyping and gene expression analyses.
-
-
-