中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

32 records (took 0.022 seconds)

    Microfluidic device and method of using the same
    3.
    发明专利
    Microfluidic device and method of using the same 审中-公开
    微流体装置及其使用方法

    公开(公告)号：JP2011097955A

    公开(公告)日：2011-05-19

    申请号：JP2011027942

    申请日：2011-02-10

    Applicant: Fluidigm Corp ,  フルイディグム コーポレイション

    Inventor： MCBRIDE LINCOLN ,  MICHAEL RUSERO ,  UNGER MARC ,  NASSEF HANY RAMEZ ,  FACER GEOFFREY

    IPC: C12M1/00 ,  B01L3/00 ,  B01L3/02 ,  B01L7/00 ,  B01L99/00 ,  B81B20060101 ,  C12N15/09 ,  C12Q1/68 ,  G01N1/10 ,  G01N37/00

    CPC classification number: B01L3/00 ,  B01L3/5027 ,  B01L3/502723 ,  B01L3/502738 ,  B01L7/52 ,  B01L2200/0642 ,  B01L2200/142 ,  B01L2200/147 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0638 ,  C12Q1/686

    Abstract: PROBLEM TO BE SOLVED: To provide a device which can be utilized to conduct a variety of nucleic acid amplification reactions, while having sufficient versatility for use in other types of analyses as well. SOLUTION: A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which reagents have been previously deposited during manufacture. The reagents become suspended once sample is introduced into the reaction site. The devices can be utilized with a variety of heating devices and thus can be used in a variety of analyses requiring temperature control, including thermocycling applications such as nucleic acid amplification reactions, genotyping, and gene expression analyses. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 要解决的问题：提供可用于进行各种核酸扩增反应的装置，同时具有用于其它类型分析的足够多功能性。 提供了各种基于弹性体的微流体装置和用于使用和制造这种装置的方法。 某些设备具有反应位置阵列以便于高通量分析。 一些装置还包括位于盲制通道末端的反应位置，在制造过程中试剂已经预先沉积。 一旦将样品引入反应部位，试剂就会悬浮。 该装置可以与各种加热装置一起使用，因此可用于需要温度控制的各种分析，包括热循环应用，如核酸扩增反应，基因分型和基因表达分析。 版权所有（C）2011，JPO＆INPIT

    ASSAY OF CLOSELY LINKED GENETIC TARGETS IN FETAL DIAGNOSIS
    4.
    发明申请
    ASSAY OF CLOSELY LINKED GENETIC TARGETS IN FETAL DIAGNOSIS 审中-公开
    诊断遗传联系遗传基因目标的方法

    公开(公告)号：WO2011053790A3

    公开(公告)日：2011-07-07

    申请号：PCT/US2010054728

    申请日：2010-10-29

    Applicant: FLUIDIGM CORP ,  ZIMMERMANN BERNHARD GEORG ,  UNGER MARC

    Inventor： ZIMMERMANN BERNHARD GEORG ,  UNGER MARC

    IPC: A61K48/00 ,  C07K14/00

    CPC classification number: C12Q1/6827 ,  C12Q2545/114

    Abstract: Methods for detecting chromosomal aneuploidy of a specified chromosome or chromosome region are provided. Also provided are methods for genetic analysis of heterogeneously sized chromosomal DNA fragments. The methods are useful for non-invasive prenatal diagnosis and other genetic analyses.

    Abstract translation: 提供了检测特定染色体或染色体区域染色体非整倍性的方法。 还提供了用于遗传分析不均匀大小的染色体DNA片段的方法。 该方法可用于非侵入性产前诊断和其他遗传分析。

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    6.
    发明申请
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 审中-公开
    晶体形成装置和系统及其制造和使用方法

    公开(公告)号：WO2005072353A3

    公开(公告)日：2007-02-22

    申请号：PCT/US2005002408

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP ,  GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    IPC: G01N15/06 ,  B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58 ,  G01N33/00 ,  G01N33/48

    CPC classification number: C12Q1/68 ,  B01L3/0293 ,  B01L3/06 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/5635 ,  B01L3/565 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2300/0816 ,  B01L2300/14 ,  B01L2400/0487 ,  B01L2400/0655 ,  C30B7/00 ,  C30B29/58 ,  Y10T436/11

    Abstract: The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure is changed therein.

    Abstract translation: 本发明提供了微流体装置及其使用方法。 本发明还提供了用于使用微流体装置的装置和系统，分析在微流体装置中进行的反应，以及用于生成，存储，组织和分析使用微流体装置产生的数据的系统。 本发明还提供了使用和制造微流体系统和装置的方法，在一些实施方案中，它们可用于晶体形成。 在一个实施例中，一种装置包括具有其中具有一个或多个流体端口的压板面的压板。 流体端口在空间上对应于微流体装置表面上的一个或多个孔。 包括用于相对于压板保持微流体装置的平台，以及用于将压板压靠在微流体装置上的压板致动器，使得压板的至少一个流体端口被推压到一个井中以形成压力室 包括井和端口，使得当压力流体通过其中一个端口被引入或从压力室移除时，流体压力在其中改变。

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    7.
    发明专利
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 未知

    公开(公告)号：SG10201506381RA

    公开(公告)日：2015-09-29

    申请号：SG10201506381R

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    IPC: B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58

    Abstract: The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure is changed therein.

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    8.
    发明专利
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 未知

    公开(公告)号：SG10201405756WA

    公开(公告)日：2014-11-27

    申请号：SG10201405756W

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    IPC: C12M1/00 ,  B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C12M3/00 ,  C30B7/00 ,  C30B29/58

    Abstract: The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure is changed therein.

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    9.
    发明专利
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 未知

    公开(公告)号：SG152261A1

    公开(公告)日：2009-05-29

    申请号：SG2009027566

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： GROSSMAN ROBERT ,  UNGER MARC ,  LAM PHILLIP ,  CHOU HOU-PU ,  KIMBALL JAKE ,  PIEPRZYK MARTIN

    IPC: B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  C30B7/00 ,  C30B29/58

    Abstract: The present invention provides for microfluidic devices and methods for their use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generated from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments, are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen against the microfluidic device so that at least one of the fluid ports of the platen is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure is changed therein.

    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME
    10.
    发明专利
    CRYSTAL FORMING DEVICES AND SYSTEMS AND METHODS FOR MAKING AND USING THE SAME 未知

    公开(公告)号：CA2554240A1

    公开(公告)日：2005-08-11

    申请号：CA2554240

    申请日：2005-01-25

    Applicant: FLUIDIGM CORP

    Inventor： PIEPRZYK MARTIN ,  KIMBALL JAKE ,  CHOU HOU-PU ,  UNGER MARC ,  LAM PHILLIP ,  GROSSMAN ROBERT

    IPC: G01N1/28 ,  B01J19/00 ,  B01L3/00 ,  B01L3/06 ,  B01L9/00 ,  B01L99/00 ,  B81B1/00 ,  B81B7/00 ,  C30B7/00 ,  C30B29/58 ,  G01N35/02 ,  G01N37/00

    Abstract: The present invention provides for microfluidic devices and methods for thei r use. The invention further provides for apparatus and systems for using the microfluidic devices, analyze reactions carried out in the microfluidic devices, and systems to generate, store, organize, and analyze data generate d from using the microfluidic devices. The invention further provides methods of using and making microfluidic systems and devices which, in some embodiments , are useful for crystal formation. In one embodiment, an apparatus includes a platen having a platen face with one or more fluid ports therein. The fluid ports spatially correspond to one or more wells on a surface of the microfluidic device. A platform for holding the microfluidic device relative to the platen is included, and a platen actuator for urging the platen again st the microfluidic device so that at least one of the fluid ports of the plate n is urged against one of the wells to form a pressure chamber comprising the well and the port, so that when pressurized fluid is introduced or removed into or from the pressure chamber through one of the ports, fluid pressure i s changed therein.

Patent Agency Ranking